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Accrued Expenses (Tables)
3 Months Ended
Mar. 31, 2017
Accrued Liabilities [Abstract]  
Schedule of Accrued Liabilities [Table Text Block]
Accrued expenses consist of the following: 
 
 
 
March 31,
 
 
 
 
 
2017
 
December 31,
 
 
 
(unaudited)
 
2016
 
Clinical Trials
 
$
406,655
 
$
770,158
 
Payroll and Benefits
 
 
252,143
 
 
668,802
 
Professional Fees
 
 
186,910
 
 
174,342
 
Short-Term Portion of Capital Lease Obligation
 
 
12,645
 
 
12,645
 
Consulting
 
 
4,500
 
 
44,983
 
Total Accrued Expenses
 
$
862,853
 
$
1,670,930