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CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($)
12 Months Ended
Dec. 31, 2015
Dec. 31, 2014
Operating activities    
Net loss $ (8,387,972) $ (1,551,508)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 1,257 1,724
Non-cash interest expense charge on beneficial conversion feature on notes 1,663,873 0
Non-cash interest expense on amortization of the debt discount 244,111 226,017
Stock-based compensation 1,224,687 26,815
Fair value adjustment of common stock warrants (223,172) (1,095,282)
Loss on cancellation of shareholders’ note receivable and related accrued interest receivable 0 200,758
Extinguishment of research liability 0 (240,000)
Changes in operating assets and liabilities:    
Accounts receivable (907,500) 0
Prepaid expenses and other current assets (95,952) (4,092)
Refundable tax credit receivable (2,357) 7,294
Other assets (1,148) (1,455)
Security deposit 0 30,000
Accounts payable (148,250) 552,256
Deferred revenue 1,907,500 0
Accrued expenses 265,754 896,856
Net cash used in operating activities (4,459,169) (950,617)
Investing activities:    
Restricted cash (20,000) 0
Net cash used in investing activities (20,000) 0
Financing activities    
Proceeds from convertible notes payable 0 1,755,767
Exercise of common stock options 26,826 6,500
Proceeds from public offerings 14,101,260 0
Offering costs (1,479,202) (1,148,994)
Payments of grants payable (32,628) 0
Net cash provided by financing activities 12,616,256 613,273
Effect of exchange rate changes on cash 90,045 3,173
Net increase (decrease) in cash 8,227,132 (334,171)
Cash, beginning of period 167,001 501,172
Cash, end of period 8,394,133 167,001
Supplemental disclosure of noncash investing and financing activities    
Conversion of non-controlling interests to common stock 6,818,732 0
Conversion of preferred stock into common stock 36,408,666 0
Exercise of common warrants 97 0
Conversion of promissory notes and accrued interest into common stock 3,532,694 0
Deemed dividend on conversion of preferred stock 8,222,008 0
Application of deferred offering costs on IPO 1,148,994 0
Warrant liability reclassed to stockholders’ equity 79,930 0
Warrants issued to related parties in conjunction with issuance of amended convertible notes 0 1,398,384
Settlement of a liability with shares 0 105,000
Accrued interest added to notes $ 0 $ 127,782