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Property and Equipment - Schedule of Property and Equipment (Detail) - USD ($)
$ in Thousands
Jun. 30, 2017
Dec. 31, 2016
Property, Plant and Equipment [Line Items]    
Total property and equipment $ 13,321 $ 13,247
Less: accumulated depreciation (10,175) (9,387)
Property and equipment, net 3,146 3,860
Office Equipment [Member]    
Property, Plant and Equipment [Line Items]    
Total property and equipment 279 266
Laboratory Equipment [Member]    
Property, Plant and Equipment [Line Items]    
Total property and equipment 4,470 4,443
Leasehold Improvements [Member]    
Property, Plant and Equipment [Line Items]    
Total property and equipment 7,711 7,683
Construction in Progress [Member]    
Property, Plant and Equipment [Line Items]    
Total property and equipment 765 759
Software [Member]    
Property, Plant and Equipment [Line Items]    
Total property and equipment $ 96 $ 96