Consolidated Statements of Operations and Comprehensive Loss - USD ($) shares in Thousands	12 Months Ended
	Dec. 31, 2023	Dec. 31, 2022	Dec. 31, 2021
Income Statement [Abstract]
Revenue from Contract with Customer, Product and Service [Extensible Enumeration]	Collaboration Revenue [Member]	Collaboration Revenue [Member]	Collaboration Revenue [Member]
Collaboration revenue	$ 17,157,000	$ 10,287,000	$ 63,175,000
Operating expenses:
Research and development	132,283,000	88,798,000	98,496,000
General and administrative	41,946,000	36,643,000	21,493,000
Acquired in-process research and development	7,339,000	0	0
Total operating expenses	181,568,000	125,441,000	119,989,000
Loss from operations	(164,411,000)	(115,154,000)	(56,814,000)
Other income (expense), net:
Interest income	18,873,000	7,550,000	431,000
Non-cash interest expense for the sale of future royalties	(18,083,000)	(21,108,000)	(1,450,000)
Other (expense) income, net	(2,000)	12,000	37,000
Total other income (expense), net	788,000	(13,546,000)	(982,000)
Loss before income taxes	(163,623,000)	(128,700,000)	(57,796,000)
Benefit (Provision) for income taxes	4,000	(24,000)	0
Net loss	(163,619,000)	(128,724,000)	(57,796,000)
Other comprehensive loss:
Unrealized gain (loss) on available for sale securities	4,449,000	(4,824,000)	(418,000)
Comprehensive loss	$ (159,170,000)	$ (133,548,000)	$ (58,214,000)
Net loss per common share:
Basic (in dollars per share)	$ (6.08)	$ (4.57)	$ (2.11)
Diluted (in dollars per share)	$ (6.08)	$ (4.57)	$ (2.11)
Weighted-average number of shares outstanding:
Basic (in shares)	26,924	28,165	27,431
Diluted (in shares)	26,924	28,165	27,431