Consolidated Statements of Cash Flows - USD ($) $ in Thousands	6 Months Ended
	Jun. 30, 2022	Jun. 30, 2021
CASH FLOWS FROM OPERATING ACTIVITIES:
Net loss	$ (68,809)	$ (18,592)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation and amortization	325	285
Stock-based compensation	14,400	7,005
Accretion/amortization of investments, net	0	293
Amortization of right-of-use assets – operating	819	751
Non-cash interest expense	10,722	0
Changes in operating assets and liabilities:
Receivables from collaborative partners	(157)	(642)
Prepaid expenses and other assets	(5,339)	(3,235)
Accounts payable and other liabilities	3,611	772
Operating lease liabilities	(733)	(250)
Net cash used in operating activities	(45,161)	(13,613)
CASH FLOWS FROM INVESTING ACTIVITIES:
Purchases of investments	(494,795)	(9,734)
Sales and maturities of investments	111,020	105,604
Purchases of property and equipment	(133)	(1,180)
Net cash (used in) provided by investing activities	(383,908)	94,690
CASH FLOWS FROM FINANCING ACTIVITIES:
Proceeds from issuance of common stock	5,709	721
Repayment of liability for sale of future royalties	(666)	0
Payments for debt issuance costs	(2)	0
Net cash provided by financing activities	5,041	721
Net (decrease) increase in cash and cash equivalents	(424,028)	81,798
Cash, cash equivalents and restricted cash, beginning of period	495,729	250,516
Cash, cash equivalents and restricted cash, end of period	71,701	332,314
Non-cash investing and financing activities:
Amounts accrued for issuance costs related to the sale of future royalties	128	0
Leased assets obtained in exchange for operating lease liabilities	0	20,685
Amounts accrued for property and equipment	0	89
Receivable related to issuance of common stock, upon exercise of stock options	$ 17	$ 38