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Equity Incentive Plans - Option Fair Value Assumptions (Details) - Options to purchase common stock - $ / shares
6 Months Ended
Jun. 30, 2019
Jun. 30, 2018
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]    
Risk-free interest rate 2.50% 2.60%
Expected volatility 68.50% 68.50%
Expected dividend yield 0.00% 0.00%
Expected term (in years) 6 years 3 months 6 years 3 months
Weighted average grant date fair value per share (in dollars per share) $ 44.02 $ 67.05