Exhibit

We consent to the incorporation by reference in the registration statement (No. 333-222868) on Form S-3ASR, and registration statement (Nos. 333-215741, 333-223446) on Form S-8 of AnaptysBio, Inc. of our report dated February 28, 2019, with respect to the consolidated balance sheets of AnaptysBio, Inc. as of December 31, 2018 and 2017, and the related consolidated statements of operations and comprehensive loss, convertible preferred stock and stockholders’ equity (deficit), and cash flows for each of the years in the three-year period ended December 31, 2018, and the related notes (collectively, the “consolidated financial statements”), and the effectiveness of internal control over financial reporting as of December 31, 2018, which reports appear in the December 31, 2018 annual report on Form 10-K of AnaptysBio, Inc.