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Quarterly Financial Information (Unaudited) - Schedule of Quarterly Financial Information (Detail) - USD ($)
3 Months Ended 12 Months Ended
Dec. 31, 2018
Sep. 30, 2018
Jun. 30, 2018
Mar. 31, 2018
Dec. 31, 2017
Sep. 30, 2017
Jun. 30, 2017
Mar. 31, 2017
Dec. 31, 2018
Dec. 31, 2017
Quarterly Financial Information Disclosure [Abstract]                    
Revenues $ 500,000               $ 500,000 $ 0
Loss from operations (14,843,267) $ (8,182,603) $ (6,335,855) $ (5,933,440) $ (5,511,786) $ (4,306,708) $ (4,181,271) $ (4,679,871) (35,295,165) (18,679,636)
Change in fair value of warrants liability             210,331 (397,235)   (186,904)
Net loss $ (14,499,609) $ (7,838,873) $ (5,965,140) $ (5,699,892) $ (5,387,698) $ (4,177,649) $ (3,879,901) $ (4,967,129) $ (34,003,514) $ (18,412,377)
Net loss per share - basic and diluted $ (0.14) $ (0.08) $ (0.06) $ (0.06) $ (0.06) $ (0.05) $ (0.05) $ (0.06) $ (0.33) $ (0.21)