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Basis of Presentation and Significant Accounting Policies - Stock-Based Compensation Expense (Detail) (USD $)
3 Months Ended 9 Months Ended
Sep. 30, 2014
Sep. 30, 2013
Sep. 30, 2014
Sep. 30, 2013
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]        
Total stock-based compensation $ 444,626 $ 46,665 $ 490,326 $ 133,305
Research and Development [Member]
       
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]        
Total stock-based compensation 35,704 23,133 59,583 63,508
General and Administrative [Member]
       
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]        
Total stock-based compensation $ 408,922 $ 23,532 $ 430,743 $ 69,797