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Basis of Presentation and Significant Accounting Policies - Stock-Based Compensation Expense (Detail) (USD $)
3 Months Ended 6 Months Ended 138 Months Ended
Jun. 30, 2013
Jun. 30, 2012
Jun. 30, 2013
Jun. 30, 2012
Jun. 30, 2013
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]          
Total stock-based compensation $ 44,888 $ 45,090 $ 86,640 $ 90,180 $ 6,048,840
Research and Development [Member]
         
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]          
Total stock-based compensation 21,612 18,303 40,375 36,605  
General and Administrative [Member]
         
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]          
Total stock-based compensation $ 23,276 $ 26,787 $ 46,265 $ 53,575