Exhibit 12.1

Athersys, Inc.

Computation of Ratio of Earnings to Fixed Charges

(amounts in thousands)

	Year Ended December 31,
	2016			2015			2014			2013			2012
Consolidated pretax loss from continuing operations	$	(15,374	)	$	(16,460	)	$	(22,335	)	$	(30,743	)	$	(14,735	)
Interest expense		10			16			13			11			8
Interest portion of rental expense		29			29			30			29			29
Total loss	$	(15,335	)	$	(16,415	)	$	(22,292	)	$	(30,703	)	$	(14,698	)
Interest expense	$	10		$	16		$	13		$	11		$	8
Interest portion of rental expense		29			29			30			29			29
Fixed Charges Requirements	$	39		$	45		$	43		$	40		$	37
Ratio of Earnings to Fixed Charges		(1	)		(1	)		(1	)		(1	)		(1	)

(1) For the years ended December 31, 2016, 2015, 2014, 2013, and 2012 there was a deficiency of earnings to cover the fixed charges of $39, $45, $43, $40 and $37, respectively