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Fair Value Measurements - Derivative Liabilities (Details)
Sep. 30, 2020
$ / shares
Feb. 19, 2020
$ / shares
Dec. 31, 2019
$ / shares
Stock Price Volatility | Compound embedded derivative with the 2013 8.00% Notes | Minimum      
Fair Value Measurement Inputs and Valuation Techniques [Line Items]      
Measurement input 0.50   0.70
Stock Price Volatility | Compound embedded derivative with the 2013 8.00% Notes | Maximum      
Fair Value Measurement Inputs and Valuation Techniques [Line Items]      
Measurement input 0.92   1.30
Stock Price Volatility | Compound embedded derivative with the Loan Agreement with Thermo | Minimum      
Fair Value Measurement Inputs and Valuation Techniques [Line Items]      
Measurement input     0.70
Stock Price Volatility | Compound embedded derivative with the Loan Agreement with Thermo | Maximum      
Fair Value Measurement Inputs and Valuation Techniques [Line Items]      
Measurement input     1.30
Risk-Free Interest Rate | Compound embedded derivative with the 2013 8.00% Notes      
Fair Value Measurement Inputs and Valuation Techniques [Line Items]      
Measurement input 0.002   0.016
Measurement input   0.014  
Risk-Free Interest Rate | Compound embedded derivative with the Loan Agreement with Thermo      
Fair Value Measurement Inputs and Valuation Techniques [Line Items]      
Measurement input     0.016
Note Conversion Price | Compound embedded derivative with the 2013 8.00% Notes      
Fair Value Measurement Inputs and Valuation Techniques [Line Items]      
Measurement input 0.69   0.69
Measurement input   0.69  
Note Conversion Price | Compound embedded derivative with the Loan Agreement with Thermo      
Fair Value Measurement Inputs and Valuation Techniques [Line Items]      
Measurement input     0.69
Discount Rate | Compound embedded derivative with the 2013 8.00% Notes      
Fair Value Measurement Inputs and Valuation Techniques [Line Items]      
Measurement input 0.23   0.27
Measurement input   0.27  
Discount Rate | Compound embedded derivative with the Loan Agreement with Thermo      
Fair Value Measurement Inputs and Valuation Techniques [Line Items]      
Measurement input     0.27
Market Price of Common Stock | Compound embedded derivative with the 2013 8.00% Notes      
Fair Value Measurement Inputs and Valuation Techniques [Line Items]      
Measurement input 0.31   0.52
Measurement input   0.42  
Market Price of Common Stock | Compound embedded derivative with the Loan Agreement with Thermo      
Fair Value Measurement Inputs and Valuation Techniques [Line Items]      
Measurement input     0.52
Compound embedded derivative with the 2013 8.00% Notes      
Fair Value Measurement Inputs and Valuation Techniques [Line Items]      
Loan interest rate, percentage 8.00%   8.00%