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Related Party Transactions - Narrative (Details)
$ in Thousands
3 Months Ended 6 Months Ended
Jun. 30, 2018
USD ($)
officer
Jun. 30, 2017
USD ($)
Jun. 30, 2018
USD ($)
officer
Jun. 30, 2017
USD ($)
Dec. 31, 2017
USD ($)
Related Party Transaction [Line Items]          
Payables to affiliates $ 286   $ 286   $ 225
Debt instrument, face amount 542,302   542,302   574,658
Derivative liabilities 120,161   120,161   226,659
Loan Agreement with Thermo          
Related Party Transaction [Line Items]          
Debt instrument, face amount 112,616   112,616   $ 106,054
Compound embedded derivative with the Thermo Loan Agreement          
Related Party Transaction [Line Items]          
Derivative liabilities $ 120,200   $ 120,200    
Thermo          
Related Party Transaction [Line Items]          
Number of executive officers | officer 2   2    
Change in fair value related to equity issuance $ 200 $ 200 $ 400 $ 400  
Thermo | Compound embedded derivative with the Thermo Loan Agreement          
Related Party Transaction [Line Items]          
Interest expense, related party $ 3,300 $ 3,000 $ 6,600 $ 5,800