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Fair Value Measurements - Schedule of Significant Quantitative Level 3 Inputs Utilized (Details) - $ / shares
6 Months Ended 12 Months Ended
Jun. 30, 2017
Dec. 31, 2016
Compound embedded derivative with the 2013 8.00% Notes    
Fair Value Measurements, Recurring and Nonrecurring, Valuation Techniques [Line Items]    
Stock Price Volatility 90.00%  
Risk-Free Interest Rate 1.20% 1.00%
Note Conversion Price (USD per share) $ 0.73 $ 0.73
Discount Rate 26.00% 25.00%
Market Price of Common Stock (USD per share) $ 2.13 $ 1.58
Compound embedded derivative with the 2013 8.00% Notes | Minimum    
Fair Value Measurements, Recurring and Nonrecurring, Valuation Techniques [Line Items]    
Stock Price Volatility   100.00%
Compound embedded derivative with the 2013 8.00% Notes | Maximum    
Fair Value Measurements, Recurring and Nonrecurring, Valuation Techniques [Line Items]    
Stock Price Volatility   110.00%
Compound embedded derivative with the Thermo Loan Agreement    
Fair Value Measurements, Recurring and Nonrecurring, Valuation Techniques [Line Items]    
Risk-Free Interest Rate 2.00% 2.20%
Note Conversion Price (USD per share) $ 0.73 $ 0.73
Discount Rate 26.00% 25.00%
Market Price of Common Stock (USD per share) $ 2.13 $ 1.58
Compound embedded derivative with the Thermo Loan Agreement | Minimum    
Fair Value Measurements, Recurring and Nonrecurring, Valuation Techniques [Line Items]    
Stock Price Volatility 40.00% 40.00%
Compound embedded derivative with the Thermo Loan Agreement | Maximum    
Fair Value Measurements, Recurring and Nonrecurring, Valuation Techniques [Line Items]    
Stock Price Volatility 85.00% 110.00%
Compound embedded derivative with the 2013 8.00% Notes    
Fair Value Measurements, Recurring and Nonrecurring, Valuation Techniques [Line Items]    
Loan interest rate 8.00%