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Fair Value Measurement - Financial Instruments at Fair Value (Details) - USD ($)
$ in Thousands
Dec. 31, 2019
Dec. 31, 2018
Assets:    
Short-term investments $ 381,074 $ 93,345
Fair Value on Recurring Basis    
Assets:    
Total assets measured and recorded at fair value 837,722 132,716
Fair Value on Recurring Basis | Agency Securities    
Assets:    
Short-term investments 10,006  
Long-term investments 15,005  
Fair Value on Recurring Basis | US Treasury Securities    
Assets:    
Short-term investments 44,286 14,328
Long-term investments   1,628
Fair Value on Recurring Basis | Corporate Bond Securities    
Assets:    
Short-term investments 319,293 38,529
Long-term investments 295,478 14,424
Fair Value on Recurring Basis | Commercial paper    
Assets:    
Short-term investments 7,489 40,488
Fair Value on Recurring Basis | Commercial paper    
Assets:    
Cash equivalents   18,267
Fair Value on Recurring Basis | Money Market Funds    
Assets:    
Cash equivalents 146,165 5,052
Fair Value on Recurring Basis | Quoted Prices in Active Markets for Identical Assets (Level 1)    
Assets:    
Total assets measured and recorded at fair value 190,451 21,008
Fair Value on Recurring Basis | Quoted Prices in Active Markets for Identical Assets (Level 1) | Agency Securities    
Assets:    
Short-term investments 0  
Long-term investments 0  
Fair Value on Recurring Basis | Quoted Prices in Active Markets for Identical Assets (Level 1) | US Treasury Securities    
Assets:    
Short-term investments 44,286 14,328
Long-term investments   1,628
Fair Value on Recurring Basis | Quoted Prices in Active Markets for Identical Assets (Level 1) | Corporate Bond Securities    
Assets:    
Short-term investments 0 0
Long-term investments 0 0
Fair Value on Recurring Basis | Quoted Prices in Active Markets for Identical Assets (Level 1) | Commercial paper    
Assets:    
Short-term investments 0 0
Fair Value on Recurring Basis | Quoted Prices in Active Markets for Identical Assets (Level 1) | Commercial paper    
Assets:    
Cash equivalents   0
Fair Value on Recurring Basis | Quoted Prices in Active Markets for Identical Assets (Level 1) | Money Market Funds    
Assets:    
Cash equivalents 146,165 5,052
Fair Value on Recurring Basis | Significant Other Observable Inputs (Level 2)    
Assets:    
Total assets measured and recorded at fair value 647,271 111,708
Fair Value on Recurring Basis | Significant Other Observable Inputs (Level 2) | Agency Securities    
Assets:    
Short-term investments 10,006  
Long-term investments 15,005  
Fair Value on Recurring Basis | Significant Other Observable Inputs (Level 2) | US Treasury Securities    
Assets:    
Short-term investments 0 0
Long-term investments   0
Fair Value on Recurring Basis | Significant Other Observable Inputs (Level 2) | Corporate Bond Securities    
Assets:    
Short-term investments 319,293 38,529
Long-term investments 295,478 14,424
Fair Value on Recurring Basis | Significant Other Observable Inputs (Level 2) | Commercial paper    
Assets:    
Short-term investments 7,489 40,488
Fair Value on Recurring Basis | Significant Other Observable Inputs (Level 2) | Commercial paper    
Assets:    
Cash equivalents   18,267
Fair Value on Recurring Basis | Significant Other Observable Inputs (Level 2) | Money Market Funds    
Assets:    
Cash equivalents $ 0 $ 0