SEC Form 4

FORM 4		UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940	OMB APPROVAL OMB Number: 3235-0287 Estimated average burden hours per response: 0.5
	Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

1. Name and Address of Reporting Person* SABBY MANAGEMENT, LLC (Last) (First) (Middle) 10 MOUNTAINVIEW ROAD SUITE 205 (Street) UPPER SADDLE RIVER NJ 07458 (City) (State) (Zip)	2. Issuer Name and Ticker or Trading Symbol Rosetta Genomics Ltd. [ ROSG ]	5. Relationship of Reporting Person(s) to Issuer (Check all applicable) Director X 10% Owner Officer (give title below) Other (specify below)
	3. Date of Earliest Transaction (Month/Day/Year) 03/14/2018
	4. If Amendment, Date of Original Filed (Month/Day/Year)	6. Individual or Joint/Group Filing (Check Applicable Line) Form filed by One Reporting Person X Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
ADR Shares (each one equal to 2 ordinary shares)	03/14/2018		P		800	A	$0.4199	751,349	I(1)(2)	See Footnotes(1)(2)
ADR Shares (each one equal to 2 ordinary shares)	03/14/2018		P		4,271	A	$0.42	755,620	I(1)(2)	See Footnotes(1)(2)
ADR Shares (each one equal to 2 ordinary shares)	03/14/2018		P		200	A	$0.42	755,820	I(1)(2)	See Footnotes(1)(2)
ADR Shares (each one equal to 2 ordinary shares)	03/14/2018		P		17,900	A	$0.424	773,720	I(1)(2)	See Footnotes(1)(2)
ADR Shares (each one equal to 2 ordinary shares)	03/14/2018		P		50,020	A	$0.4201	823,740	I(1)(2)	See Footnotes(1)(2)
ADR Shares (each one equal to 2 ordinary shares)	03/15/2018		P		15,025	A	$0.4205	838,765	I(1)(2)	See Footnotes(1)(2)
ADR Shares (each one equal to 2 ordinary shares)	03/15/2018		P		34	A	$0.42	838,799	I(1)(2)	See Footnotes(1)(2)
ADR Shares (each one equal to 2 ordinary shares)	03/15/2018		P		3,566	A	$0.42	842,365	I(1)(2)	See Footnotes(1)(2)
ADR Shares (each one equal to 2 ordinary shares)	03/15/2018		P		13,545	A	$0.42	855,910	I(1)(2)	See Footnotes(1)(2)
ADR Shares (each one equal to 2 ordinary shares)	03/15/2018		P		14,400	A	$0.4205	870,310	I(1)(2)	See Footnotes(1)(2)

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares

1. Name and Address of Reporting Person* SABBY MANAGEMENT, LLC (Last) (First) (Middle) 10 MOUNTAINVIEW ROAD SUITE 205 (Street) UPPER SADDLE RIVER NJ 07458 (City) (State) (Zip) Relationship of Reporting Person(s) to Issuer Director X 10% Owner Officer (give title below) Other (specify below)

1. Name and Address of Reporting Person* Sabby Healthcare Master Fund, Ltd. (Last) (First) (Middle) C/O SABBY MANAGEMENT, LLC 10 MOUNTAINVIEW ROAD, SUITE 205 (Street) UPPER SADDLE RIVER NJ 07458 (City) (State) (Zip) Relationship of Reporting Person(s) to Issuer Director X 10% Owner Officer (give title below) Other (specify below)

Explanation of Responses:

1. This Form 4 is being filed by Sabby Healthcare Master Fund, Ltd. ("SHMF"), Sabby Volatility Warrant Master Fund, Ltd. ("SVWMF"), Sabby Management, LLC ("Advisor") and Hal Mintz. Advisor is the investment manager of SHMF and SVWMF. Mr. Mintz is manager of Advisor.

2. The amounts reported herein reflect the entire amount of Issuer's ADR shares held by SHMF and SVWMF as of each transaction date. Each of Advisor and Mr. Mintz disclaims, for purposes of Section 16 of the Securities Exchange Act of 1934 ("Section 16"), beneficial ownership of such securities, except to the extent of its/his pecuniary interest therein, and this report shall not be deemed as an admission that either Advisor or Mr. Mintz is the beneficial owner of such securities for purposes of Section 16 or otherwise.

	/s/ Robert Grundstein, COO and General Counsel of Sabby Management, LLC	03/16/2018
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
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