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Unaudited Condensed Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
6 Months Ended
Jun. 30, 2022
Jun. 30, 2021
Cash flows used in operating activities:    
Net loss $ (19,294) $ (26,247)
Adjustments to reconcile net loss to net cash used in operating activities:    
Stock-based compensation 3,821 5,738
Operating lease right-of-use asset 683 401
Depreciation 109 87
Amortization of premium on marketable debt securities 756 747
Changes in operating assets and liabilities:    
Prepaid expenses and other current assets (716) (1,848)
Other assets 54 144
Accounts payable (562) 489
Accrued expenses (272) (475)
Operating lease liabilities (663) (430)
Net cash used in operating activities (16,084) (21,394)
Cash flows from investing activities:    
Purchase of marketable debt securities (14,428) (99,574)
Proceeds from maturity and redemption of marketable debt securities 28,706  
Purchase of property and equipment (31) (616)
Net cash provided by/(used in) investing activities 14,247 (100,190)
Cash flows from financing activities:    
Repurchase of shares in connection with settlement of RSUs (72) (228)
Net cash used in financing activities (72) (228)
Net decrease in cash and cash equivalents and restricted cash (1,909) (121,812)
Cash and cash equivalents and restricted cash - beginning of year 36,469 169,393
Cash and cash equivalents and restricted cash - end of period 34,560 47,581
Reconciliation of cash and cash equivalents and restricted cash to the condensed consolidated balance sheets:    
Cash and cash equivalents 33,815 46,836
Restricted cash
Restricted cash, non-current 745 745
Cash and cash equivalents and restricted cash $ 34,560 $ 47,581