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Stock-Based Compensation (Tables)
12 Months Ended
Dec. 31, 2021
Share-based Payment Arrangement [Abstract]  
Schedule of restricted stock unit activities
   Restricted
Stock Units
  

Weighted
Average Grant
Date Fair Value

 
Non-vested 12/31/2020   274,616   $29.95 
Granted   10,500    11.16 
Forfeited   
-
    
-
 
Vested   (188,915)   29.46 
Non-vested 12/31/2021   96,201   $28.87 

 

Schedule of the fair value of stock options granted
   For the Years Ended
December 31,
 
   2021   2020 
Exercise price   $ 6.56 - $ 19.82     $ 17.84 - $ 51.12  
Dividend yield   0.00%   0.00%
Expected volatility   89.00% - 98.00%   95.00% - 101.00%
Risk-free interest rate   0.45% - 1.33%   0.28% - 1.69%
Expected life (in years)   5.27 - 6.08    5.27 - 6.08 

 

Schedule of stock option activities
   Number of
Options
   Weighted
Average
Exercise
Price
   Weighted
Average
Remaining
Contractual
Term (years)
   Aggregate
Intrinsic
Value (1)
 
Outstanding 12/31/2020   674,039   $25.23    9.06   $2,311 
Granted   861,850    16.32    
-
    
-
 
Exercised   
-
    
-
    
-
    
-
 
Forfeited   (168,196)   17.62    
-
    
-
 
Expired   (11,054)   26.15    
-
    
-
 
Outstanding at December 31, 2021   1,356,639   $20.51    8.59   $1 
                     
Vested or expected to vest at December 31, 2021   1,356,639   $20.51    8.59   $
-
 
Exercisable as of 12/31/2021   407,981   $21.97    7.83   $
-
 

 

(1)Aggregate intrinsic value represents the difference between the exercise price of the option and the closing market price of our common stock on December 31, 2021. The intrinsic value of options exercised during the year ended December 31, 2021 was $0 as no options were exercised. The intrinsic value of options exercised during the year ended December 31, 2020 was $696.

 

Schedule of total stock-based compensation costs
   For the Years Ended
December 31,
 
   2021   2020 
RSUs  $4,520   $6,357 
Stock options   5,842    3,389 
Total  $10,362   $9,746 

 

Schedule of stock-based compensation expense
   For the Years Ended
December 31,
 
   2021   2020 
Research and development  $1,409   $741 
General and administrative   8,953    9,005 
Total  $10,362   $9,746