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Condensed Consolidated Statements of Cash Flows (unaudited) - USD ($)
$ in Thousands
3 Months Ended
Mar. 31, 2021
Mar. 31, 2020
Cash flows used in operating activities:    
Net loss $ (13,465) $ (10,060)
Adjustments to reconcile net loss to net cash used in operating activities:    
Stock based compensation 2,740 2,798
Operating lease right-of-use asset 55 20
Depreciation 32 50
Amortization of premium on bonds 283  
Changes in operating assets and liabilities:    
Prepaid expenses and other current assets (1,971) (77)
Other Assets 65  
Accounts payable 938 1,934
Accrued expenses (545) (1,811)
Operating lease liabilities (52)  
Net cash used in operating activities (11,920) (7,146)
Cash flows (used in)/provided by investing activities:    
Cash and restricted cash acquired in connection with the reverse merger with ArTara Therapeutics, Inc.   3,719
Purchase of marketable debt securities, available-for-sale (97,959)  
Purchase of property and equipment (290) (247)
Net cash (used in)/provided by investing activities (98,249) 3,472
Cash flows (used in)/provided by financing activities:    
Proceeds from - ArTara Private Placement, net of offering costs   1,867
Proceeds from - Common Stock in Proteon Private Placement, net of offering costs   12,413
Proceeds from - Series 1 Convertible Preferred Stock in Proteon Private Placement, net of offering costs   25,319
Repurchase of shares in connection with settlement of RSUs (228)  
Repayments under short-term debt   (370)
Net cash (used in)/provided by financing activities (228) 39,229
Net (decrease)/increase in cash and cash equivalents and restricted cash (110,397) 35,555
Cash and cash equivalents and restricted cash - beginning of year 169,393 564
Cash and cash equivalents and restricted cash - end of period 58,996 36,119
Reconciliation of cash and cash equivalents and restricted cash to the consolidated balance sheets:    
Cash and cash equivalents 58,201 36,069
Restricted cash 50 50
Restricted cash, long-term 745  
Cash and cash equivalents and restricted cash 58,996 36,119
Cash paid for:    
Interest   8
Income Taxes
Non-cash investing and financing activities:    
Deferred offering costs recognized that were previously recorded in accrued expenses   122
Purchase of insurance agreement with notes payable   1,669
Common stock issued in connection with the reverse merger with ArTara Therapeutics, Inc.   $ 34,533