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Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2019
Dec. 31, 2018
Operating activities    
Net loss $ (14,992) $ (20,729)
Reconciliation of net loss to net cash used in operating activities:    
Depreciation 279 115
Amortization of premium/discount on available-for-sale securities (4) (51)
Foreign currency remeasurement (loss) (25)
Stock-based compensation 943 3,429
Changes in:    
Prepaid expenses and other assets 608 141
Operating lease right-of-use asset 200
Interest receivable 17 49
Accounts payable and accrued expenses (2,497) (6,162)
Operating lease liability (200)
Net cash used in operating activities (15,646) (23,233)
Investing activities    
Purchases of available-for-sale investments (15,443)
Proceeds from maturities of available-for-sale investments 2,500 31,990
Proceeds from sale of available-for-sale investments 1,999
Purchase of property and equipment (16) (119)
Net cash provided by (used in) investing activities 2,484 18,427
Financing activities    
Proceeds from issuance of common stock, net of issuance costs 2,853
Proceeds from issuance of common stock under ESPP 132
Net cash provided by financing activities 2,985
Effect of exchange rate changes on cash 22
Decrease in cash, cash equivalents and restricted cash (13,162) (1,799)
Cash, cash equivalents and restricted cash, beginning of period 19,393 21,192
Cash, cash equivalents and restricted cash, end of period $ 6,231 $ 19,393