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Note 4 - Property and Equipment, Net - Summary of Property and Equipment (Details) - USD ($)
$ in Thousands
Jun. 30, 2019
Dec. 31, 2018
Property and equipment $ 1,104 $ 1,090
Accumulated depreciation (1,021) (827)
Property and equipment, net 83 263
Computer Equipment and Software [Member]    
Property and equipment 225 211
Furniture and Fixtures [Member]    
Property and equipment 365 365
Laboratory Equipment [Member]    
Property and equipment $ 514 $ 514