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Note 4 - Property and Equipment, Net (Tables)
12 Months Ended
Dec. 31, 2018
Notes Tables  
Property, Plant and Equipment [Table Text Block]
    As of December 31,
    2018   2017
         
Computer equipment and software   $
211
    $
192
 
Furniture, fixtures, and other    
365
     
302
 
Laboratory equipment    
514
     
477
 
     
1,090
     
971
 
Accumulated depreciation    
(827
)    
(712
)
Property and equipment, net   $
263
    $
259