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Note 12 - Net Loss Per Share Attributable to Common Stockholders - Common Stock Equivalents Excluded From Calculation of Net Loss Per Share (Details) - shares
12 Months Ended
Dec. 31, 2017
Dec. 31, 2016
Dec. 31, 2015
Antidilutive Securities (in shares) 24,793,847 2,166,254 2,200,369
Convertible Preferred Stock [Member]      
Antidilutive Securities (in shares) 22,112,775
Employee Stock Option [Member]      
Antidilutive Securities (in shares) 2,681,072 2,166,254 2,200,369