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Note 13 - Quarterly Financial Information (Unaudited, in Thousands, Except Share and Per Share Data) (Tables)
 12 Months Ended
Dec. 31, 2017
Notes Tables  
Quarterly Financial Information [Table Text Block]
    Three Months Ended
    March 31,
2017		   June 30,
2017		   September 30,
2017		   December 31,
2017
Operating expenses   $
6,480
     $
5,986
     $
12,306
 
   $
5,590
  
Net loss attributable to common stockholders    
(6,498
 )    
(5,608
 )    
(19,054
)
    
(5,551
 )
Net loss per share attributable to common stockholders:                                
Basic and Diluted   $
(0.39
 )   $
(0.33
 )   $
(1.08
)
   $
(0.33
 )
Weighted-average common shares outstanding used in net loss per share attributable to common stockholders:                                
Basic and Diluted    
16,636,201
      
17,207,672
      
17,619,418
(a)
    
17,619,418
  
    Three Months Ended
    March 31,
2016		   June 30,
2016		   September 30,
2016		   December 31,
2016
Operating expenses   $
6,819
     $
7,854
     $
7,166
     $
6,866
  
Net loss attributable to common stockholders    
(6,552
 )    
(7,905
 )    
(7,107
 )    
(6,962
 )
Net loss per share attributable to common stockholders:                                
Basic and Diluted   $
(0.40
 )   $
(0.48
 )   $
(0.43
 )   $
(0.42
 )
Weighted-average common shares outstanding used in net loss per share attributable to common stockholders:                                
Basic and Diluted    
16,507,586
      
16,561,239
      
16,582,276
      
16,595,502