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Note 5 - Property and Equipment, Net (Tables)
 12 Months Ended
Dec. 31, 2017
Notes Tables  
Property, Plant and Equipment [Table Text Block]
    As of December 31,
    2017   2016
         
Computer equipment and software   $
192
     $
141
  
Furniture, fixtures, and other    
302
      
318
  
Laboratory equipment    
477
      
478
  
     
971
      
937
  
Accumulated depreciation    
(712
 )    
(565
 )
Property and equipment, net   $
259
     $
372