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Note 7 - Stock-based Compensation - Stock Option Activity for Employees and Non-employees (Details) - USD ($)
$ / shares in Units, $ in Thousands
9 Months Ended 12 Months Ended
Sep. 30, 2017
Dec. 31, 2016
Options Outstanding, Beginning Balance (in shares) 2,166,254  
Options Outstanding, Weighted Average Exercise Price, Beginning Balance (in dollars per share) $ 8.55  
Options Outstanding, Weighted-average Remaining Contractual Term, Beginning Balance (Year) 7 years 146 days 7 years 36 days
Options Outstanding, Aggregate Intrinsic Value, Beginning Balance $ 140 $ 124
Options Granted (in shares) 719,337  
Options Granted, Weighted Average Exercise Price (in dollars per share)  
Options Exercised (in shares) (74,001)  
Options Exercised, Weighted Average Exercise Price (in dollars per share)  
Options Forfeited (in shares) (30,272)  
Options Forfeited, Weighted Average Exercise Price (in dollars per share)  
Options Expired (in shares) (97,406)  
Options Expired, Weighted Average Exercise Price (in dollars per share)  
Options Outstanding, Ending Balance (in shares) 2,683,912 2,166,254
Options Outstanding, Weighted Average Exercise Price, Ending Balance (in dollars per share) $ 7.18 $ 8.55
Options Exercisable (in shares) 1,384,925  
Options Exercisable, Weighted Average Exercise Price (in dollars per share) $ 8  
Options Exercisable, Weighted-average Remaining Contractual Term (Year) 6 years 73 days  
Options Exercisable, Aggregate Intrinsic Value $ 98  
Options Vested or Expected to Vest (in shares) [1] 2,683,912  
Options Vested or Expected to Vest, Weighted Average Exercise Price (in dollars per share) [1] $ 7.18  
Options Vested or Expected to Vest, Weighted-average Remaining Contractual Term (Year) [1] 7 years 146 days  
Options Vested or Expected to Vest, Aggregate Intrinsic Value [1] $ 140  
[1] Represents the number of vested options at September 30, 2017 plus the number of unvested options expected to vest based on the unvested options outstanding at September 30, 2017.