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Note 8 - Net Loss Per Share Attributable to Common Stockholders (Tables)
6 Months Ended
Jun. 30, 2017
Notes Tables  
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block]
    Three Months Ended June 30,   Six Months Ended June 30,
    2017   2016   2017   2016
Outstanding stock options    
2,783,570
     
2,234,934
     
2,783,570
     
2,234,934
 
     
2,783,570
     
2,234,934
     
2,783,570
     
2,234,934