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Note 6 - Stock-based Compensation
3 Months Ended
Mar. 31, 2017
Notes to Financial Statements  
Disclosure of Compensation Related Costs, Share-based Payments [Text Block]
6.
Stock-based Compensation
 
Stock Options
 
The following table summarizes stock option activity for employees and non-employees:
 
    Options   Weighted-
Average
Exercise
Price
  Weighted-
Average
Remaining
Contractual
Term (years)
  Aggregate
Intrinsic
Value
                 
Outstanding at December 31, 2016    
2,166,254
    $
8.55
     
7.1
    $
124
 
Granted    
659,342
    $
2.05
     
 
     
 
 
Exercised    
(74,001
)   $
1.45
     
 
     
 
 
Outstanding at March 31, 2017    
2,751,595
    $
7.18
     
7.6
    $
64
 
Exercisable at March 31, 2017    
1,242,299
    $
7.35
     
6.0
    $
64
 
Vested or expected to vest at March 31, 2017 (1)    
2,751,595
    $
7.18
     
7.6
    $
64
 
___________________
(1)
Represents the number of vested options at
March
31,
2017
plus the number of unvested options expected to vest based on the unvested options outstanding at
March
31,
2017.
 
Employee Stock Purchase Plan
 
The
2014
Employee Stock Purchase Plan (ESPP) initially authorized the issuance of up to
140,500
shares of Common Stock. The number of shares increases each
January
1,
commencing on
January
1,
2015
and ending on (and including)
January
1,
2024,
by an amount equal to the lesser of
one
percent of the outstanding shares as of the end of the immediately preceding fiscal year,
281,000
shares, or any lower amount determined by the Company’s Board of Directors prior to each such
January
1st.
The Company’s Board of Directors has determined there was to be no increase on
January
1,
2017.
As of
March
31,
2017,
the
2014
ESPP authorized the issuance of up to
304,991
shares of Common Stock. The
fifth
offering under the
2014
ESPP began on
January
1,
2017
and ends on
June
30,
2017.
No
shares were issued during the
three
months ended
March
31,
2017
under the
2014
ESPP.
 
Common Stock
 
The Company has the following shares reserved for future issuance:
 
    March 31,
2017
  December, 31
2016
         
Stock-based compensation awards    
3,572,611
     
2,982,470
 
Employee Stock Purchase Plan    
292,821
     
292,821
 
Total    
3,865,432
     
3,275,291