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Note 11 - Net Loss Per Share Attributable to Common Stockholders - Common Stock Equivalents Excluded from Calculation of Net Loss Per Share (Details) - shares
12 Months Ended
Dec. 31, 2016
Dec. 31, 2015
Dec. 31, 2014
Antidilutive Securities (in shares) 2,166,254 2,200,369 9,720,683
Common Stock Warrants [Member]      
Antidilutive Securities (in shares) 659,806 [1]
Employee Stock Option [Member]      
Antidilutive Securities (in shares) 2,166,254 2,200,369 1,235,526
Convertible Debt Securities [Member]      
Antidilutive Securities (in shares) 243,876 [1]
Convertible Preferred Stock [Member]      
Antidilutive Securities (in shares) 7,581,475 [1]
[1] These instruments were either exercised or converted to Common Stock during 2014.