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Note 4 - Property and Equipment, Net - Summary of Property and Equipment (Details) - USD ($)
$ in Thousands
Dec. 31, 2016
Dec. 31, 2015
Property and equipment $ 937 $ 665
Accumulated depreciation (565) (441)
Property and equipment, net 372 224
Computer Equipment and Software [Member]    
Property and equipment 141 167
Furniture and Fixtures [Member]    
Property and equipment 318 244
Laboratory Equipment [Member]    
Property and equipment $ 478 $ 254