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Note 11 - Net Loss Per Share Attributable to Common Stockholders (Tables)
12 Months Ended
Dec. 31, 2016
Notes Tables  
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block]
    Year Ended December 31,
    2016   2015   2014
Convertible preferred stock    
-
     
-
     
7,581,475
(a)
Common stock warrants    
-
     
-
     
659,806
(a)
Outstanding stock options    
2,166,254
     
2,200,369
     
1,235,526
 
Convertible notes    
-
     
-
     
243,876
(a)
     
2,166,254
     
2,200,369
     
9,720,683