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Note 12 - Quarterly Financial Information (Unaudited, in Thousands, Except Share and Per Share Data)
 12 Months Ended
Dec. 31, 2016
Notes to Financial Statements  
Quarterly Financial Information [Text Block]
12.
  
Quarterly Financial Information (unaudited, in thousands, except share and per share data)
 
The following table contains selected quarterly financial information from
2016
and
2015.
The Company believes that the following information reflects all normal recurring adjustments necessary for a fair statement of the information for the periods presented. The operating results for any quarter are not necessarily indicative of results for any future period.
 
    Three Months Ended
    March 31,   June 30,   September 30,   December 31,
    2016   2016   2016   2016
Operating expenses   $
6,819
     $
7,854
     $
7,166
     $
6,866
  
Net loss attributable to common stockholders    
(6,552
 )    
(7,905
 )    
(7,107
 )    
(6,962
 )
Net loss per share attributable to common stockholders:                                
Basic and Diluted   $
(0.40
 )   $
(0.48
 )   $
(0.43
 )   $
(0.42
 )
Weighted-average common shares outstanding used in net loss per share attributable to common stockholders:                                
Basic and Diluted    
16,507,586
      
16,561,239
      
16,582,276
      
16,595,502
  
 
 
    Three Months Ended
    March 31,   June 30,   September 30,   December 31,
    2015   2015   2015   2015
Operating expenses   $
4,620
     $
4,981
     $
5,082
     $
6,187
  
Net loss attributable to common stockholders    
(4,580
 )    
(5,072
 )    
(5,383
 )    
(6,342
 )
Net loss per share attributable to common stockholders:                                
Basic and Diluted   $
(0.28
 )   $
(0.31
 )   $
(0.33
 )   $
(0.38
 )
Weighted-average common shares outstanding used in net loss per share attributable to common stockholders:                                
Basic and Diluted    
16,448,688
      
16,449,937
      
16,466,945
      
16,490,430