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Note 6 - Stock-based Compensation
6 Months Ended
Jun. 30, 2016
Notes to Financial Statements  
Disclosure of Compensation Related Costs, Share-based Payments [Text Block]
6.
Stock-based Compensation
 
Stock Options
 
The following table summarizes stock option activity for employees and non-employees:
 
    Options   Weighted-
Average
Exercise
Price
  Weighted-
Average
Remaining
Contractual
Term (years)
  Aggregate
Intrinsic
Value
                 
Outstanding at December 31, 2015     2,200,369     $ 8.52       7.8     $ 15,705  
Granted     114,162     $ 6.77                  
Exercised     (72,508 )   $ 1.91                  
Cancelled or forfeited     (7,089 )   $ 4.92                  
Outstanding at June 30, 2016     2,234,934     $ 8.66       7.6     $ 4,470  
Exercisable at June 30, 2016     997,718     $ 5.57       5.9     $ 3,577  
Vested or expected to vest at June 30, 2016 (1)     2,064,955     $ 8.41       7.4     $ 4,373  
____________________
(1) Represents the number of vested options at June 30, 2016 plus the number of unvested options expected to vest based on the unvested options outstanding at June 30, 2016 .
 
Employee Stock Purchase Plan
 
The 2014 ESPP initially authorized the issuance of up to 140,500 shares of Common Stock. The number of shares increases each January 1, commencing on January 1, 2015 and ending on (and including) January 1, 2024, by an amount equal to the lesser of one percent of the outstanding shares as of the end of the immediately preceding fiscal year, 281,000 shares, or any lower amount determined by the Company’s Board of Directors prior to each such January 1st. The Company’s Board of Directors has determined there was to be no increase on January 1, 2016. As of June 30, 2016, the 2014 ESPP authorized the issuance of up to 304,991 shares of Common Stock. The first offering under the 2014 ESPP began on January 1, 2015 and ended on June 30, 2015. During the six months ended June 30, 2016, 674 shares were issued under the 2014 ESPP with 296,685 shares remaining for future issuance under the plan as of June 30, 2016. The Company incurred $16,000 and $32,000 in stock-based compensation expense related to the 2014 ESPP for the three and six months ended June 30, 2016, respectively. The Company incurred $11,000 and $22,000 in stock-based compensation expense related to the 2014 ESPP for the three and six months ended June 30, 2015, respectively.
 
Common Stock
 
The Company has the following shares reserved for future issuance:
 
    June 30,
2016
  December 31,
2015
         
Stock-based compensation awards     3,007,453       2,419,901  
Employee Stock Purchase Plan     296,685       297,359  
Total     3,304,138       2,717,260