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Note 8 - Common Stock Equivalents Excluded from Calculation of Net Loss Per Share (Details) - shares
3 Months Ended
Mar. 31, 2016
Mar. 31, 2015
Employee Stock Option [Member]    
Antidilutive Securities (in shares) 2,203,975 1,635,219
Outstanding ESPP Shares [Member]    
Antidilutive Securities (in shares) 8,841 2,859
Antidilutive Securities (in shares) 2,212,816 1,638,078