Note 2 - Summary of Significant Accounting Policies - Property and Equipment Useful Lives (Details)	12 Months Ended
Dec. 31, 2018
Computer Equipment and Software [Member]
Property and equipment, useful life (Year)	3 years
Furniture and Fixtures [Member]
Property and equipment, useful life (Year)	5 years
Laboratory Equipment [Member]
Property and equipment, useful life (Year)	7 years

Useful life of long lived, physical assets used in the normal conduct of business and not intended for resale, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days. Examples include, but not limited to, land, buildings, machinery and equipment, office equipment, furniture and fixtures, and computer equipment.

No definition available.

Name:	us-gaap_PropertyPlantAndEquipmentUsefulLife
Namespace Prefix:	us-gaap_
Data Type:	xbrli:durationItemType
Balance Type:	na
Period Type:	duration