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Note 9 - Equity Incentive Plans - Summary of Stock Option Activity (Details)
$ / shares in Units, $ in Thousands
6 Months Ended 12 Months Ended
Jun. 30, 2021
USD ($)
$ / shares
shares
Dec. 31, 2020
USD ($)
$ / shares
shares
Options Outstanding (in shares) | shares 826,769  
Options Outstanding, Weighted Average Exercise Price (in dollars per share) | $ / shares $ 32.72  
Options Outstanding, Weighted Average Remaining Contractual Life (Year) 6 years 9 months 6 years 5 months 26 days
Options Outstanding, Aggregate Intrinsic Value | $ $ 0 $ 1,541
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Gross (in shares) | shares 59,818  
Options Granted, Weighted Average Exercise Price (in dollars per share) | $ / shares $ 17.72  
Options Exercised (in shares) | shares 0  
Options Exercised, Weighted Average Exercise Price (in dollars per share) | $ / shares $ 0  
Options Forfeited, expired or cancelled (in shares) | shares (84,132)  
Options Forfeited, expired or cancelled, Weighted Average Exercise Price (in dollars per share) | $ / shares  
Options Outstanding (in shares) | shares 802,455 826,769
Options Outstanding, Weighted Average Exercise Price (in dollars per share) | $ / shares $ 33.11 $ 32.72
Options Vested and expected to vest (in shares) | shares 802,455  
Options Vested and expected to vest, Weighted Average Exercise Price (in dollars per share) | $ / shares $ 33.11  
Options Vested and expected to vest, Weighted Average Remaining Contractual Life (Year) 6 years 9 months  
Options Vested and expected to vest, Aggregate Intrinsic Value | $ $ 0  
Options Exercisable (in shares) | shares 759,743  
Options Exercisable, Weighted Average Exercise Price (in dollars per share) | $ / shares $ 33.19  
Options Exercisable, Weighted Average Remaining Contractual Life (Year) 6 years 7 months 28 days  
Options Exercisable, Aggregate Intrinsic Value | $ $ 0