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Note 8 - Equity Incentive Plans - Fair Value Assumptions for Stock Options (Details) - USD ($)
$ / shares in Units, $ in Thousands
9 Months Ended
Sep. 30, 2022
Sep. 30, 2021
Disclosure Text Block [Abstract]    
Weighted-average exercise price per share $ 0.81 $ 17.72
Weighted-average expected term (years) 5 years 9 months 21 days 5 years
Weighted-average risk-free interest rate 2.30% 0.88%
Weighted-average expected dividend yield $ 0 $ 0
Weighted-average volatility 73.66% 76.05%