10-Q/A

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

WASHINGTON, DC 20549

FORM 10-Q/A

(Amendment No. 1)

(Mark One)

xQUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934

For the quarterly period ended March 31, 2016

OR

oTRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934

For the transition period from                    to

Commission File Number: 001-35518

SUPERNUS PHARMACEUTICALS, INC.

(Exact name of registrant as specified in its charter)

Delaware	20-2590184
(State or other jurisdiction of	(I.R.S. Employer
incorporation or organization)	Identification No.)
1550 East Gude Drive, Rockville, MD	20850
(Address of principal executive offices)	(Zip Code)

(301) 838-2500

(Registrant’s telephone number, including area code)

Indicate by check mark whether the registrant: (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding 12 months (or for such shorter period that the registrant was required to file such reports), and (2) has been subject to such filing requirements for the past 90 days.  o Yes  x No

Indicate by check mark whether the registrant has submitted electronically and posted on its corporate Website, if any, every Interactive Data File required to be submitted and posted pursuant to Rule 405 of Regulation S-T during the preceding 12 months (or for such shorter period that the registrant was required to submit and post such files).  x Yes  o No

Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, or a smaller reporting company. See definition of “large accelerated filer,” “accelerated filer,” and “smaller reporting company” in Rule 12b-2 of the Exchange Act. (Check one):

Large accelerated filer x	Accelerated filer o
Non-accelerated filer o	Smaller reporting company o
(Do not check if a smaller reporting company)

Indicate by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Exchange Act).  o Yes  x No

The number of outstanding shares of the registrant’s common stock, par value $0.001 per share, as of the close of business on January 17, 2017 was 50,121,242.

Explanatory Note

Unless the context requires otherwise, the words “Supernus,” “we,” “our,” and “the Company” refer to Supernus Pharmaceuticals, Inc. and its subsidiaries.

Supernus Pharmaceuticals, Inc. (the Company) is filing this Amendment No. 1 on Form 10-Q/A (the Amended Form 10-Q) to its Quarterly Report on Form 10-Q for the fiscal quarter ended March 31, 2016 (the Original Form 10-Q), which was originally filed with the U.S. Securities and Exchange Commission (SEC) on May 10, 2016 (the Original Filing Date), to reflect the restatement of consolidated financial statements (Restatement) as described below.

In this Amended Form 10-Q for the fiscal quarter ended March 31, 2016, we are restating our previously issued and unaudited consolidated financial statements and the related disclosures for the three month periods ended March 31, 2016 and March 31, 2015. As discussed in further detail below and in Note 2 to the accompanying consolidated financial statements, the Restatement is the result of a misapplication in the guidance on accounting for revenue recognition related to the sale of future revenues (as described below). We assessed the impact of this misapplication on our prior interim and annual consolidated financial statements and concluded that the impact was material to these consolidated financial statements. Consequently, we have restated the prior period consolidated financial statements identified above. All amounts in this Amended Form 10-Q affected by the Restatement reflect such amounts as restated.  For a more detailed explanation of these matters and resulting restatements, please see Part I, Item 1: Financial Statements — Note 2 to the Consolidated Financial Statements; Part I, Item 2: Management’s Discussion and Analysis of Financial Condition and Results of Operations — Restatement of Previously Issued Consolidated Financial Statements; and Part I, Item 4: Controls and Procedures.

For the convenience of the reader, this Amended Form 10-Q sets forth the Original Form 10-Q for the three month period ended March 31, 2016 in its entirety, as amended by and to reflect the Restatement and includes certain restated information for the three month period ended March 31, 2015.

Background of Restatement

In July 2014, the Company entered into a royalty monetization transaction and recorded the transaction with healthcare Royalty Partners III, L.P. (HC Royalty) as revenue referencing guidance under ASC 605, “Revenue Recognition.” In August 2016, the Company was informed by its former independent registered public accounting firm, Ernst and Young LLP (EY), that a royalty monetization transaction for another client had recently been reviewed by the SEC’s Office of the Chief Accountant (the OCA). The OCA had concluded that that transaction should have been recorded as a liability rather than as revenue. Accordingly, Supernus undertook to re-evaluate the accounting for the 2014 transaction.

Having conferred with the Company’s prior auditor, EY, and the company’s current auditor KPMG LLP (KPMG), in October 2016, the Company submitted to the OCA a request to post clear the Company’s accounting for the royalty monetization transaction from 2014. In its submission, the Company concluded that the terms and conditions of the agreement met the criteria for revenue recognition under SAB 104 and ASC 605-10. On November 9, 2016, the OCA completed its review and informed the Company that the royalty monetization transaction should have been recorded as a debt obligation in 2014 in accordance with ASC 470-10-25. As a result, on November 10, 2016, the Company’s Audit Committee concluded that the Company’s consolidated financial statements for the years ended December 31, 2014 and December 31, 2015, and related reports of the Company’s independent registered public accounting firms thereon, and the interim quarterly reports in those years beginning with the third quarter of 2014, and the interim quarterly reports for the first and second quarters in 2016 should no longer be relied upon and should be restated.

The Company is restating in this Amended Form 10-Q its consolidated financial statements for the three month periods ended March 31, 2016 and March 31, 2015. The adjustments to our consolidated financial statements related to the 2014 royalty monetization transaction resulted in the following changes:

·The $30.0 million proceeds of the transaction have now been recorded in the third quarter of 2014 as a non-recourse debt, rather than revenue;

·Revenue and operating income in the third quarter of 2014 have been reduced by approximately $30.0 million; and

·Royalties received by the counterparty to the royalty monetization transaction are now recognized by the Company as non-cash royalty revenue. The $30.0 million of non-recourse liability is reduced by the same amount, and then increased by the non-cash implied interest expense to be recognized.

The revisions referenced above result in noncash financial statement corrections, principally reducing net income and increasing liability, but will have no impact on the Company’s current or previously reported cash and marketable securities position and no impact on net product sales.

In connection with the Restatement, the Company also made the following corrections:

·Recording current tax expenses related to an increase in our reserve for an uncertain tax position related to alternative minimum taxes in the fourth quarter of 2014 that had been previously recognized in the second quarter of 2015;

·An adjustment to the Statement of Cash Flows for the quarter ended March 31, 2016 to adjust cash used in investing activities, with an offset to cash provided by operations for certain accrued legal fees that have been deferred;

·The correction of an immaterial error, to correctly recognize stock compensation expense associated with the January 2014 stock option awards to the Board. These options have a twelve month vesting period, though the Company originally began recognizing compensation expense over a four-year vesting term. This error was corrected during 2015. Correcting this immaterial error results in an increase in selling, general, and administrative expense (SG&A) in 2014, and a corresponding decrease in SG&A expense in 2015; and

·The reclassification of a Certificate of Deposit (CD), originally purchased during the first quarter of 2015 and continually renewed on a quarterly basis, as a current marketable security. This CD has 91 days to maturity and the Company incorrectly classified this amount as cash and cash equivalents on the balance sheets at March 31, 2015, June 30, 2015, September 30, 2015 and December 31, 2015. We have corrected the balance sheets in all periods to reflect the reclassification from cash and cash equivalents to current marketable securities.

An explanation of the impact of each of these revisions on our financial statements is contained in Note 2 to the consolidated financial statements contained in Part I, Item 1: Financial Statements.

Items Amended in this Quarterly Report on Form 10-Q/A

The following items of this Amended Form 10-Q include restated financial data: (i) Part I, Item 1: Financial Statements; and (ii) Part I, Item 2: Management’s Discussion and Analysis of Financial Condition and Results of Operations. In addition, Part I, Item 4: Controls and Procedures includes a statement of material weakness covering our controls over financial reporting.

Information not affected by the Restatement is unchanged and reflects the disclosures made as of the Original Filing Date and is not intended to speak as of any subsequent date. No statements made herein should be assumed to be accurate as of any subsequent date. Accordingly, this Amended Form 10-Q should be read in conjunction with our subsequent filings with the SEC, as information in such filings may update or supersede certain information contained in this Amended Form 10-Q.

Restatement of Other Financial Statements

In addition to the restated financial information for three month periods ended March 31, 2016 and March 31, 2015, included in this Amended Form 10-Q, the Restatement requires the restatement of our audited consolidated financial statements and related disclosures for the years ended December 31, 2015 and December 31, 2014 and our unaudited condensed consolidated financial statements and related disclosures for the quarters ended September 30, 2014, June 30, 2015, September 30, 2015, and June 30, 2016.  Concurrently with this filing, we are filing the following amended Forms 10-K and 10-Q with respect to these periods to address the corrections:

·Form 10-Q/A for the quarter ended September 30, 2015, which contains restated unaudited condensed consolidated financial statements and related disclosures for the three and nine month periods ended September 30, 2015 and 2014;

·Form 10-K/A for the year ended December 31, 2015, which contains restated audited consolidated financial statements and related disclosures for the years ended December 31, 2015 and 2014; and

·Form 10-Q/A for the quarter ended June 30, 2016, which contains restated unaudited condensed consolidated financial statements and related disclosures for the three and six month periods ended June 30, 2016 and 2015.

Internal Control Considerations

Management has assessed the effect of the restatement on the Company’s internal control over financial reporting and believes that this restatement represents a material weakness in its internal control over financial reporting for all periods under restatement. A material weakness is a deficiency, or combination of deficiencies, in internal control over financial reporting, such that there is a reasonable possibility that a material misstatement of the annual or interim consolidated financial statements will not be prevented or detected on a timely basis. For a discussion of management’s consideration of the material weakness identified, see Part I, Item 4: Controls and Procedures included in this Quarterly Report. In addition, this Amended Form 10-Q includes currently-dated certifications from the Company’s Chief Executive Officer and Chief Financial Officer, as required by Sections 302 and 906 of the Sarbanes-Oxley Act of 2002.

SUPERNUS PHARMACEUTICALS, INC.

FORM 10-Q/A — QUARTERLY REPORT

FOR THE QUARTERLY PERIOD ENDED MARCH 31, 2016

TABLE OF CONTENTS

	Page No.
PART I — FINANCIAL INFORMATION
Item 1. Financial Statements
Consolidated Balance Sheets (as Restated) as of March 31, 2016 (Unaudited), December 31, 2015 and March 31, 2015 (Unaudited)	1
Consolidated Statements of Operations (as Restated) for the three month periods ended March 31, 2016 and 2015 (Unaudited)	2
Consolidated Statements of Comprehensive Income (as Restated) for the three month periods ended March 31, 2016, and 2015 (Unaudited)	3
Consolidated Statements of Cash Flows (as Restated) for the three month periods ended March 31, 2016 and 2015 (Unaudited)	4
Notes to Consolidated Financial Statements (as Restated) (Unaudited)	5
Item 2. Management’s Discussion and Analysis of Financial Condition and Results of Operations (Restated)	19
Item 3. Quantitative and Qualitative Disclosures about Market Risk	32
Item 4. Controls and Procedures (Restated)	33
PART II — OTHER INFORMATION
Item 1. Legal Proceedings	34
Item 1A. Risk Factors	36
Item 2. Unregistered Sales of Equity Securities and Use of Proceeds	36
Item 3. Defaults Upon Senior Securities	37
Item 4. Mine Safety Disclosures	37
Item 5. Other Information	37
Item 6. Exhibits	37
SIGNATURES	38

PART I — FINANCIAL INFORMATION

Supernus Pharmaceuticals, Inc.

Consolidated Balance Sheets (Restated)

(in thousands, except share amounts)

	March 31,			December 31,			March 31
	2016			2015			2015
	(unaudited)						(unaudited)
Assets
Current assets:
Cash and cash equivalents	$	19,830		$	33,498		$	25,158
Marketable securities	25,427			28,692			39,678
Accounts receivable, net	30,651			25,908			19,271
Inventories, net	13,044			12,587			13,702
Prepaid expenses and other current assets	5,003			5,261			3,640
Total current assets	93,955			105,946			101,449
Long term marketable securities	68,790			55,009			27,315
Property and equipment, net	3,866			3,874			2,481
Deferred legal fees	11,444			22,503			7,672
Intangible assets, net	16,108			976			167
Other non-current assets	311			318			321
Total assets	$	194,474		$	188,626		$	139,405
Liabilities and stockholders’ equity
Current liabilities:
Accounts payable	$	2,646		$	4,314		$	859
Accrued sales deductions	28,697			26,794			10,025
Accrued expenses	22,915			25,153			16,482
Non-recourse liability related to sale of future royalties — current portion	1,067			497			—
Deferred licensing revenue	208			176			143
Total current liabilities	55,533			56,934			27,509
Deferred licensing revenue, net of current portion	1,658			1,390			1,238
Convertible notes, net	5,627			7,085			11,476
Non-recourse liability related to sale of future royalties — long term	29,621			30,031			30,179
Other non-current liabilities	4,391			4,325			2,561
Derivative liabilities	535			854			2,691
Total liabilities	97,365			100,619			75,654
Stockholders’ equity:
Common stock, $0.001 par value, 130,000,000 shares authorized at March 31, 2016, December 31, 2015 and March 31, 2015; 49,421,236, 49,004,674 and 47,513,429 shares issued and outstanding at March 31, 2016, December 31, 2015 and March 31, 2015, respectively	49			49			48
Additional paid-in capital	267,576			263,955			252,483
Accumulated other comprehensive income (loss)	168			(488		)	(65		)
Accumulated deficit	(170,684		)	(175,509		)	(188,715		)
Total stockholders’ equity	97,109			88,007			63,751
Total liabilities and stockholders’ equity	$	194,474		$	188,626		$	139,405

See accompanying notes.

1

Supernus Pharmaceuticals, Inc.

Consolidated Statements of Operations (Restated)

(in thousands, except share and per share data)

	Three Months ended March 31,
	2016			2015
	(unaudited)
Revenue
Net product sales	$	43,025		$	28,097
Royalty revenue	1,119			605
Licensing revenue	50			36
Total revenue	44,194			28,738
Costs and expenses
Cost of product sales	2,035			1,618
Research and development	10,562			3,683
Selling, general and administrative	25,160			19,403
Total costs and expenses	37,757			24,704
Operating income	6,437			4,034
Other income (expense)
Interest income	331			113
Interest expense	(179		)	(381		)
Interest expense non-recourse liability related to sale of future royalties	(1,279		)	(759		)
Changes in fair value of derivative liabilities	101			(49		)
Loss on extinguishment of debt	(382		)	(2,134		)
Other expense	(4		)	—
Total other expense	(1,412		)	(3,210		)
Earnings before income taxes	5,025			824
Income tax expense	200			86
Net income	$	4,825		$	738
Income per common share:
Basic	$	0.10		$	0.02
Diluted	$	0.08		$	0.02
Weighted-average number of common shares outstanding:
Basic	49,240,099			44,563,299
Diluted	51,152,072			44,901,298

See accompanying notes.

2

Supernus Pharmaceuticals, Inc.

Consolidated Statements of Comprehensive Income (Restated)

(in thousands)

	Three Months ended March 31,
	2016		2015
	(unaudited)
Net income	$	4,825	$	738
Other comprehensive income:
Unrealized net gain on marketable securities	656		89
Other comprehensive income:	656		89
Comprehensive income	$	5,481	$	827

See accompanying notes.

3

Supernus Pharmaceuticals, Inc.

Consolidated Statements of Cash Flows (Restated)

(in thousands)

	Three Months ended March 31,
	2016			2015
	(unaudited)
Cash flows from operating activities
Net income	$	4,825		$	738
Adjustments to reconcile net income to net cash (used in) provided by operating activities:
Loss on extinguishment of debt	382			2,134
Change in fair value of derivative liability	(101		)	49
Depreciation and amortization	429			214
Non cash interest expense, net/interest income, net	155			463
Non-recourse liability related to sale of future royalties	1,279			759
Non-cash royalty revenue	(1,119		)	(605		)
Share-based compensation expense	1,359			902
Changes in operating assets and liabilities:
Accounts receivable	(4,744		)	(2,001		)
Inventories	(457		)	(261		)
Prepaid expenses and other assets	260			38
Accounts payable	(1,691		)	(1,004		)
Accrued sales deduction	1,903			1,505
Accrued expenses	(5,995		)	(1,883		)
Deferred licensing revenue	300			(36		)
Other non-current liabilities	73			(1,277		)
Net cash (used in) provided by operating activities	(3,142		)	(265		)
Cash flows from investing activities
Purchases of marketable securities	(17,335		)	(17,967		)
Sales and maturities of marketable securities	7,400			8,731
Purchases of property and equipment	(279		)	(189		)
Deferred legal fees	(436		)	(1,695		)
Net cash used in investing activities	(10,650		)	(11,120		)
Cash flows from financing activities
Proceeds from issuance of common stock	124			147
Net cash provided by financing activities	124			147
Net change in cash and cash equivalents	(13,668		)	(11,238		)
Cash and cash equivalents at beginning of period	33,498			36,396
Cash and cash equivalents at end of period	$	19,830		$	25,158
Noncash financial activity:
Conversion of convertible notes and interest make-whole	$	2,138		$	21,176
Deferred legal fees included in accounts payable and accrued expenses	$	3,779		$	3,176

See accompanying notes.

4

Supernus Pharmaceuticals, Inc.

Notes to Consolidated Financial Statements

For the Three Months ended March 31, 2016 and 2015

(unaudited)

1.  Organization and Business

Supernus Pharmaceuticals, Inc. (the Company) was incorporated in Delaware on March 30, 2005, and commenced operations on December 22, 2005. The Company is a specialty pharmaceutical company focused on developing and commercializing products for the treatment of central nervous system (CNS) diseases, including neurological and psychiatric disorders. The Company markets two epilepsy products, Oxtellar XR and Trokendi XR, and has several proprietary product candidates in clinical development that address the psychiatry market.

The Company commenced the commercialization of Oxtellar XR and Trokendi XR in 2013.

2.  Restatement of Financial Statements

In July 2014, the company entered into a royalty monetization transaction and recorded the transaction as revenue. In October 2016, the Company submitted to the U.S. Securities and Exchange Commission’s (the SEC) Office of the Chief Accountant (the OCA) a request for post-accounting review of the royalty monetization transaction from 2014. On November 9, 2016, the OCA completed its review and informed the Company that the royalty monetization transaction should have been recorded as a debt obligation in 2014. As a result, on November 10, 2016, the Company’s Audit Committee concluded that the Company’s financial statements for the years ended December 31, 2014 and December 31, 2015, and the interim quarterly reports in those years beginning with the third quarter of 2014, and the interim quarterly reports for the first and second quarters in 2016 and related reports of the Company’s independent registered public accounting firms thereon, should no longer be relied upon and will be restated.

The Company is restating in this Quarterly Report its financial statements for the three month period ended March 31, 2016 and March 31, 2015. This restatement results in noncash, financial statement corrections and will have no impact on the Company’s current or previously reported cash and marketable securities position or net product sales.

The Company has also made corrections to reflect (i) the recording during the fourth quarter of 2014 of a current tax expense related to an increase in our reserve for an uncertain tax position related to alternative minimum taxes that had been previously recognized in the second quarter of 2015 and (ii) an increase in Selling, General and Administrative Expense in 2014 which is fully offset by a corresponding decrease in Selling, General and Administrative Expense in 2015. This adjustment is the result of the recognition of stock compensation expense over a period of twelve months as opposed to four years related to certain option grants granted in January 2014. Additionally, during the first quarter of 2015, the Company purchased a Certificate of Deposit (CD) that has been continually renewed on a quarterly basis. This CD has 91 days to maturity and the Company incorrectly classified this amount as cash and cash equivalents on the balance sheets at March 31, 2015, June 30, 2015, September 30, 2015 and December 31, 2015. We have corrected the balance sheets in all periods to reflect the reclassification from cash and cash equivalents to current marketable securities. An adjustment was made to the Statement of Cash Flows for the three months ended March 31, 2015 to change cash used in investing activities, with an offset to cash provided by operations for certain accrued legal fees that have been deferred.

The impact of the restatement and other corrections on the condensed Consolidated Balance Sheet, Consolidated Statement of Operations and Consolidated Statement of Cash Flows as of and for the three month periods ended March 31, 2016 and March 31, 2015 is presented below, in thousands except share and per share data.

5

Three Months Ended March 31, 2016

Consolidated Statement of Operations	As Previously			Restatement			Other
(unaudited)	Reported			Adjustments			Corrections		As Restated
Royalty revenue	$	—		$	1,119		$		$	1,119
Total revenue	43,075			1,119					44,194
Operating income	5,318			1,119					6,437
Interest expense — non-recourse liability related to sale of future royalties	—			(1,279		)			(1,279		)
Total other expense	(133		)	(1,279		)			(1,412		)
Earnings before income taxes	5,185			(160		)			5,025
Income tax expense	198						2		200
Net income	4,987			(160		)	(2	)	4,825

Three Months Ended March 31, 2016

	As Previously			Restatement	Other
Consolidated Statements of Cash Flows (unaudited)	Reported			Adjustments	Corrections		As Restated
Net cash used in investing activities	$	(11,304	)		$	654	$	(10,650	)
Net change in cash and cash equivalents	(14,322		)		654		(13,668		)

As of March 31, 2016

	As Previously			Restatement		Other
Consolidated Balance Sheet (unaudited)	Reported			Adjustments		Corrections			As Restated
Accrued expenses	$	22,573				$	342		$	22,915
Non-recourse liability related to sale of future royalties — current portion	—			1,067					1,067
Total current liabilities	54,124			1,067		342			55,533
Non-recourse liability related to sale of future royalties — long term	—			29,621					29,621
Total liabilities	66,335			30,688		342			97,365
Accumulated deficit	(139,654		)	(30,688	)	(342		)	(170,684		)
Total stockholders’ equity	128,139			(30,688	)	(342		)	97,109

Three Months Ended March 31, 2015

Consolidated Statement of Operations	As Previously			Restatement			Other
(unaudited)	Reported			Adjustments			Corrections		As Restated
Royalty revenue	$	—		$	605		$		$	605
Total revenue	28,133			605					28,738
Selling, general and administrative	19,402						1		19,403
Total costs and expenses	24,703						1		24,704
Operating income	3,430			605			(1	)	4,034
Interest expense — non-recourse liability related to sale of future royalties	—			(759		)			(759		)
Total other expense	(2,451		)	(759		)			(3,210		)
Earnings before income taxes	979			(154		)	(1	)	824
Income tax expense	62						24		86
Net Income	917			(154		)	(25	)	738

6

Three Months Ended March 31, 2015

	As Previously			Restatement	Other
Consolidated Statements of Cash Flows (unaudited)	Reported			Adjustments	Corrections			As Restated
Net cash provided by (used in) operating activities	$	503			$	(768	)	$	(265	)
Net cash used in investing activities	(11,236		)		116			(11,120		)
Net change in cash and cash equivalents	(10,586		)		(652		)	(11,238		)

As of March 31, 2015

	As Previously			Restatement		Other
Consolidated Balance Sheet (unaudited)	Reported			Adjustments		Corrections			As Restated
Cash and cash equivalents	$	25,810				$	(652	)	$	25,158
Marketable securities	39,026					652			39,678
Accrued expenses	15,828					654			16,482
Total current liabilities	26,855					654			27,509
Non-recourse liability related to sale of future royalties — long term	—			30,179					30,179
Total liabilities	45,053			30,179		422			75,654
Additional paid-in capital	252,341					142			252,483
Accumulated deficit	(157,740		)	(30,179	)	(796		)	(188,715		)
Total stockholders’ equity	94,584			(30,179	)	(654		)	63,751

As of December 31, 2015

	As Previously			Restatement		Other
Consolidated Balance Sheet	Reported			Adjustments		Corrections			As Restated
Cash and cash equivalents	$	34,152				$	(654	)	$	33,498
Marketable securities	28,038					654			28,692
Accrued expenses	24,813					340			25,153
Non-recourse liability related to sale of future royalties — current portion	—			497					497
Total current liabilities	56,097			497		340			56,934
Non-recourse liability related to sale of future royalties — long term	—			30,031					30,031
Total liabilities	69,751			30,528		340			100,619
Accumulated deficit	(144,641		)	(30,528	)	(340		)	(175,509		)
Total stockholders’ equity	118,875			(30,528	)	(340		)	88,007

3.  Summary of Significant Accounting Policies

Basis of Presentation

The Company’s consolidated financial statements include the accounts of Supernus Pharmaceuticals, Inc. and Supernus Europe Ltd., collectively referred to herein as “Supernus” or “the Company.” All significant intercompany transactions and balances have been eliminated in consolidation. The Company’s unaudited consolidated financial statements have been prepared in accordance with the requirements of the U.S. Securities and Exchange Commission (SEC) for interim financial information.

As permitted under Generally Accepted Accounting Principles in the United States (U.S. GAAP), certain notes and other information have been omitted from the interim unaudited consolidated financial statements presented in this Quarterly Report on Form 10-Q/A.

7

Therefore, these financial statements should be read in conjunction with the Company’s Annual Report on Form 10-K/A for the year ended December 31, 2015 filed with the SEC.

In the opinion of management, the consolidated financial statements reflect all adjustments necessary to fairly present the Company’s financial position, results of operations, and cash flows for the periods presented. These adjustments are of a normal recurring nature.  The Company currently operates in one business segment.

The results of operations for the three months ended March 31, 2016 are not necessarily indicative of the Company’s future financial results.

Marketable Securities

Marketable securities consist of investments in U.S. Treasuries, various U.S. governmental agency debt securities, corporate bonds and other fixed income securities. The Company’s investments are classified as available for sale. Such securities are carried at estimated fair value, with any unrealized holding gains or losses reported, net of any tax effects reported, as accumulated other comprehensive income, which is a separate component of stockholders’ equity. Realized gains and losses, and declines in value judged to be other-than-temporary, if any, are included in consolidated results of operations. A decline in the market value of any available for sale security below cost that is deemed to be other-than-temporary results in a reduction in fair value, which is charged to earnings in that period, and a new cost basis for the security is established. Dividend and interest income is recognized when earned. The cost of securities sold is calculated using the specific identification method. The Company places all investments with government, industrial, or financial institutions whose debt is rated as investment grade. The Company classifies all available-for-sale marketable securities with maturities greater than one year from the balance sheet date as non-current assets.

The Company established the Supernus Supplemental Executive Retirement Plan (SERP) for the sole purpose of receiving funds for executives from a previous SERP and providing a continuing deferral program under the Supernus SERP. As of March 31, 2016 and December 31, 2015, the fair value of the SERP was $255,000 and $263,000, respectively. These were held in mutual fund investments. The fair value of these assets is included within other non-current assets on the consolidated balance sheets. A corresponding noncurrent liability is also included in the consolidated balance sheets to reflect the Company’s obligation for the SERP. The Company has not made, and has no plans to make, contributions to the SERP. The securities are restricted in nature and can only be used for purposes of paying benefits under the SERP.

Accounts Receivable, net

Accounts receivable are reported on the consolidated balance sheets at outstanding amounts, less an allowance for doubtful accounts and discounts. The Company extends credit without requiring collateral. The Company writes off uncollectible receivables when the likelihood of collection is remote. The Company evaluates the collectability of accounts receivable on a regular basis. An allowance, when needed, is based upon various factors including the financial condition and payment history of customers, an overall review of collections experience on other accounts, and economic factors or events expected to affect future collections experience. No accounts have been written off as of March 31, 2016 and December 31, 2015. The Company recorded an allowance of approximately $4.0 million and $3.8 million for expected sales discounts as of March 31, 2016 and December 31, 2015, respectively.

Deferred Financing Costs

Deferred financing costs consist of financing costs incurred by the Company in connection with the closing of the Company’s 7.50% Convertible Senior Secured Notes and Secured Notes Payable (see Note 9). The Company amortizes deferred financing costs over the term of the related debt using the effective interest method. When extinguishing debt, the related deferred financing costs are written off.

Revenue Recognition

Revenue from product sales is recognized when persuasive evidence of an arrangement exists; delivery has occurred and title to the product and associated risk of loss has passed to the customer; the price is fixed or determinable; collection from the customer has been reasonably assured; all performance obligations have been met; and returns and allowances can be reasonably estimated. Product sales are recorded net of estimated rebates, chargebacks, discounts, co-pay assistance and other deductions as well as estimated product returns (collectively, “sales deductions”).

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Our products are distributed through wholesalers and pharmaceutical distributors. Each of these wholesalers and distributors will take title and ownership to the product upon physical receipt of the product and then distribute our products to pharmacies.

Royalty Revenue

In the third quarter of 2014, the Company received a $30.0 million payment pursuant to a royalty agreement related to the purchase by HC Royalty of certain of the Company’s rights under the agreement with United Therapeutics Corporation related to the commercialization of Orenitram. We have recorded a non-recourse liability related to this transaction and have begun to amortize this amount to recognize royalty revenue as royalties are received by HC Royalty from United Therapeutics. We also recognize non-cash interest expense related to this liability that accrues at an effective interest rate determined based on projections of HC Royalty’s rate of return. We recognized royalty revenue of $1.1 million and $0.6 million for the three months ended March 31, 2016 and 2015, respectively. We recognized interest expense of $1.3 million and $0.8 million for the three months ended March 31, 2016 and 2015, respectively.

Sales Deductions

Allowances for estimated sales deductions are provided for the following:

·Rebates.  Rebates include mandated discounts under the Medicaid Drug Rebate Program, the Medicare coverage gap program, as well as negotiated discounts with commercial healthcare providers. Rebates are amounts owed after the final dispensing of products to a benefit plan participant and are based upon contractual agreements or legal requirements with the public sector (e.g. Medicaid) and with private sector benefit providers. The allowance for rebates is based on statutory and contractual discount rates and expected claimed rebates paid based on a plan provider’s utilization. Rebates are generally invoiced and paid quarterly in arrears so that the accrual balance consists of an estimate of the amount expected to be incurred for the current quarter’s activity, plus an accrual balance for known or estimated prior quarters’ unpaid rebates. If actual future rebates vary from estimates, we may need to adjust balances of such rebates to reflect the actual expenditures of the Company with respect to these programs, which would affect revenue in the period of adjustment.

·Chargebacks.  Chargebacks are discounts that occur when contracted customers purchase directly from an intermediary distributor or wholesaler. Contracted customers, which currently consist primarily of Public Health Service institutions and federal government entities purchasing via the Federal Supply Schedule, generally purchase the product at a discounted price. The distributor or wholesaler, in turn, charges back the difference between the price initially paid by the distributor or wholesaler and the discounted price paid to the distributor or wholesaler by the customer. The allowance for distributor/wholesaler chargebacks is based on known sales to contracted customers.

·Distributor/Wholesaler deductions and discounts.  U.S. specialty distributors and wholesalers are offered various forms of consideration including allowances, service fees and prompt payment discounts as consideration for distributing our products. Distributor allowances and service fees arise from contractual agreements with distributors and are generally a percentage of the purchase price paid by the distributors and wholesalers. Wholesale customers are offered a prompt pay discount for payment within a specified period.

·Co-pay assistance.  Patients who pay in cash or have commercial insurance and meet certain eligibility requirements may receive co-pay assistance from the Company. The intent of this program is to reduce the patient’s out of pocket costs. Liabilities for co-pay assistance are based on actual program participation and estimates of program redemption using data provided by third-party administrators.

·Returns.  Sales of our products are not subject to a general right of return; however, the Company will accept product that is damaged or defective when shipped directly from our warehouse. The Company will accept expired product six months prior and up to 12 months subsequent to its expiry date. Product that has been used to fill patient prescriptions is no longer subject to any right of return.

Milestone Payments

Milestone payments on licensing agreements are recognized as revenue when the collaborative partner acknowledges completion of the milestone and substantive effort (i.e., effort consistent with amount of the milestone) was necessary to achieve the milestone.

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Management may recognize revenue contingent upon the achievement of a milestone in its entirety in the period in which the milestone is achieved only if the milestone meets all the criteria to be considered substantive. The Company recorded no milestone revenue during the three months ended March 31, 2016 and March 31, 2015.

Cost of Product Sales

The cost of product sales consists primarily of materials, third-party manufacturing costs, freight and distribution costs, allocation of labor, quality control and assurance, and other manufacturing overhead costs.

Income Taxes

The Company utilizes the asset and liability method of accounting for income taxes. Under this method, deferred tax assets and liabilities are determined based on differences between financial reporting and tax reporting bases of assets and liabilities and are measured using enacted tax rates and laws that are expected to be in effect when the differences are expected to reverse. Valuation allowances are established to reduce deferred tax assets to the amounts expected to be realized.

The Company accounts for uncertain tax positions in its consolidated financial statements when it is more-likely-than-not that the position will be sustained upon examination by the tax authorities. Such tax positions must initially and subsequently be measured as the largest amount of tax benefit that has a greater than 50% likelihood of being realized upon ultimate settlement with the tax authority assuming full knowledge of the position and relevant facts. The Company’s policy is to recognize any interest and penalties related to income taxes in income tax expense.

Recently Issued Accounting Pronouncements

In March 2016, the Financial Accounting Standards Board (FASB) issued Accounting Standards Update (ASU) No. 2016-09, “Compensation- Stock Compensation (Topic 718): Improvements to Employee Share-Based Payment Accounting” (ASU 2016-09). The standard is intended to simplify several areas of accounting for share-based compensation arrangements, including the income tax impact, classification on the statement of cash flows and forfeitures. ASU 2016-09 is effective for fiscal years, and interim periods within those years, beginning after December 15, 2016, and early adoption is permitted. We are currently evaluating the impact that the standard will have on our consolidated financial statements.

In February 2016, the FASB issued ASU No. 2016-02, “Lease (Topic 842)”. The standard requires a lessee to recognize assets and liabilities on the balance sheet for leases with lease terms greater than 12 months. ASU 2016-02 is effective for fiscal years, and interim periods within those years, beginning after December 15, 2018, and early adoption is permitted. We are currently evaluating the impact that the standard will have on our consolidated financial statements.

In April 2015, the FASB issued ASU No. 2015-03, “Simplifying the Presentation of Debt Issuance Costs.” This ASU more closely aligns the treatment of debt issuance costs with debt discounts and premiums and requires debt issuance costs be presented as a direct deduction from the carrying amount of the related debt. The amendments in this ASU are effective for financial statements issued for fiscal years beginning after December 15, 2015 and interim periods within those fiscal years. This guidance has been applied on a retrospective basis and the impact is reflected in the as previously reported column in Note 2. The adoption of ASU No. 2015-03 resulted in a reclassification of deferred financing costs of $232,000 and $104,000 from asset to liability classification on the Company’s consolidated financial statements as of March 31, 2015 and December 31, 2015, respectively.

4.  Fair Value of Financial Instruments

The fair value of an asset or liability should represent the price that would be received to sell an asset or paid to transfer a liability in an orderly transaction between market participants. Such transactions to sell an asset or transfer a liability are assumed to occur in the principal or most advantageous market for the asset or liability. Accordingly, fair value is determined based on a hypothetical transaction at the measurement date, considered from the perspective of a market participant rather than from a reporting entity’s perspective.

The Company reports assets and liabilities that are measured at fair value using a three tier or level fair value hierarchy that prioritizes the inputs used to measure fair value. This hierarchy maximizes the use of observable inputs and minimizes the use of unobservable inputs. The three levels of inputs used to measure fair value are as follows:

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·Level 1—Inputs are unadjusted quoted prices in active markets for identical assets that the Company has the ability to access at the measurement date.

·Level 2—Inputs are quoted prices for similar assets and liabilities in active markets, quoted prices for identical or similar assets or liabilities in markets that are not active, inputs other than quoted prices that are observable for the asset or liability (interest rates, yield curves, etc.) and inputs that are derived principally from or corroborated by observable market data by correlation or other means (market corroborated inputs).

·Level 3—Unobservable inputs that reflect the Company’s own assumptions, based on the best information available, including the Company’s own data.

In accordance with the fair value hierarchy described above, the following tables show the fair value of the Company’s financial assets and liabilities that are required to be measured at fair value, in thousands:

	Fair Value Measurements at
	March 31, 2016
	(unaudited)
					Significant
	Total Carrying		Quoted Prices		Other		Significant
	Value at		in Active		Observable		Unobservable
	March 31,		Markets		Inputs		Inputs
	2016		(Level 1)		(Level 2)		(Level 3)
Assets:
Cash and cash equivalents	$	19,830	$	19,830	$	—	$	—
Marketable securities	25,427		654		24,773		—
Long term marketable securities	68,790		—		68,790		—
Marketable securities - restricted (SERP)	255		—		255		—
Total assets at fair value	$	114,302	$	20,484	$	93,818	$	—
Liabilities:
Derivative liabilities	$	535	$	—	$	—	$	535

	Fair Value Measurements at
	December 31, 2015
	(restated)
					Significant
	Total Carrying		Quoted Prices		Other		Significant
	Value at		in Active		Observable		Unobservable
	December 31,		Markets		Inputs		Inputs
	2015		(Level 1)		(Level 2)		(Level 3)
Assets:
Cash and cash equivalents	$	33,498	$	33,498	$	—	$	—
Marketable securities	28,692		654		28,038		—
Long term marketable securities	55,009		—		55,009		—
Marketable securities - restricted (SERP)	263		—		263		—
Total assets at fair value	$	117,462	$	34,152	$	83,310	$	—
Liabilities:
Derivative liabilities	$	854	$	—	$	—	$	854

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	Fair Value Measurements at
	March 31, 2015
	(unaudited) (restated)
					Significant
	Total Carrying		Quoted Prices		Other		Significant
	Value at		in Active		Observable		Unobservable
	March 31,		Markets		Inputs		Inputs
	2015		(Level 1)		(Level 2)		(Level 3)
Assets:
Cash and cash equivalents	$	25,158	$	25,158	$	—	$	—
Marketable securities	39,678		652		39,026		—
Long term marketable securities	27,315		—		27,315		—
Marketable securities - restricted (SERP)	267		—		267		—
Total assets at fair value	$	92,418	$	25,810	$	66,608	$	—
Liabilities:
Derivative liabilities	$	2,691	$	—	$	—	$	2,691

The fair value of the restricted marketable securities is included within other non-current assets in the consolidated balance sheets.

The Company’s Level 1 assets include cash held with banks, a CD and money market funds.

Level 2 assets include the SERP assets, commercial paper and investment grade corporate bonds and other fixed income securities. Level 2 securities are valued using third-party pricing sources that apply applicable inputs and other relevant data into their models to estimate fair value.

Level 3 liabilities include the estimated fair value of the interest make-whole liability associated with the Company’s 7.50% Convertible Senior Secured Notes due 2019 (the Notes), which are recorded as derivative liabilities.

The fair value of the interest make-whole liability of the Notes was calculated using a binomial-lattice model with the following key assumptions as of March 31, 2016, unaudited:

Volatility	45%
Stock Price as of March 31, 2016	$15.21 per share
Credit Spread	900 bps
Term	1.1 years
Dividend Yield	0.0%

Significant changes to these assumptions could result in increases/decreases to the fair value of the derivative liabilities.

Changes in the fair value of the interest make-whole liability are recognized as a component of Other Income (Expense) in the Consolidated Statements of Operations. The following table presents information about the Company’s Level 3 liabilities as of December 31, 2015 and March 31, 2016 that are included in the Non-Current Liabilities section of the Consolidated Balance Sheets, in thousands:

	Three Months ended
	March 31, 2016
	(unaudited)
Balance at December 31, 2015	$	854
Changes in fair value of derivative liabilities included in earnings	(101		)
Reduction due to conversion of debt to equity	(218		)
Balance at March 31, 2016	$	535

The carrying value, face value and estimated fair value of the Notes was approximately $5.6 million, $6.6 million and $20.0 million, respectively, as of March 31, 2016. The fair value was estimated based on actual trade information as well as quoted prices provided

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by bond traders, which would be characterized within Level 2 of the fair value hierarchy. This fair value amount gives recognition to the value of the interest make-whole liability and the value of the conversion option. Upon issuance these were accounted for as derivative liabilities and additional paid-in-capital, respectively.

The carrying amounts of other financial instruments, including accounts receivable, accounts payable and accrued expenses approximate fair value due to their short-term maturities.

Unrestricted marketable securities held by the Company were as follows, in thousands:

At March 31, 2016 (unaudited):

Available for Sale	Amortized Cost		Gross Unrealized Gains	Gross Unrealized Losses		Fair Value
Corporate debt securities	$	94,049	300	(132	)	$	94,217

At December 31, 2015 (restated):

Available for Sale	Amortized Cost		Gross Unrealized Gains	Gross Unrealized Losses		Fair Value
Corporate debt securities	$	84,189	5	(493	)	$	83,701

At March 31, 2015 (unaudited) (restated):

Available for Sale	Amortized Cost		Gross Unrealized Gains		Gross Unrealized Losses			Fair Value
Corporate debt securities	$	67,058	$	15	$	(80	)	$	66,993

The contractual maturities of the unrestricted available for sale marketable securities held by the Company were as follows, in thousands:

	March 31, 2016
	(unaudited)
Less Than 1 Year	$	25,427
1-5 years	68,790
Greater Than 5 Years	—
Total	$	94,217

The Company has not experienced any other-than-temporary losses on its marketable securities and restricted marketable securities. The cost of securities sold is calculated using the specific identification method.

5. Inventories

Inventories consist of the following, in thousands:

	March 31,		December 31,		March 31,
	2016		2015		2015
	(unaudited)				(unaudited)
Raw materials	$	2,371	$	2,887	3,132
Work in process	4,264		3,946		6,328
Finished goods	6,409		5,754		4,242
	$	13,044	$	12,587	$	13,702

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6.  Property and Equipment

Property and equipment consist of the following, in thousands:

	March 31,			December 31,			March 31,
	2016			2015			2015
	(unaudited)						(unaudited)
Computer equipment	$	1,130		$	1,112		$	932
Software	1,463			307			314
Lab equipment and furniture	5,878			5,667			5,235
Leasehold improvements	2,642			2,642			2,446
Construction in progress	8			1,114			—
	11,121			10,842			8,927
Less accumulated depreciation and amortization	(7,255		)	(6,968		)	(6,446		)
	$	3,866		$	3,874		$	2,481

Depreciation and amortization expense on property and equipment was approximately $287,000 and $156,000 for the three months ended March 31, 2016 and March 31, 2015, respectively.

7.  Deferred Legal Fees and Intangible Assets

Deferred legal fees have been incurred in connection with patents for Oxtellar XR and Trokendi XR. As of March 31, 2016 and December 31, 2015, the Company had deferred legal fees of $11.4 million and $22.5 million, respectively.

The following sets forth the gross carrying amount and related accumulated amortization of the intangible asset, in thousands:

		March 31, 2016
		(unaudited)				December 31, 2015
	Weighted-	Gross Carrying		Accumulated		Gross Carrying		Accumulated
	Average Life	Amount		Amortization		Amount		Amortization
Capitalized patent defense costs	9.5	$	16,267	$	159	$	994	$	18

The Company prevailed in a lawsuit related to Oxtellar XR in February 2016, at which time the Company began amortizing the costs associated with that litigation.

The net book value of intangible assets was $16.1 million as of March 31, 2016 and was $1.0 million as of December 31, 2015. The increase in intangible assets reflects the successful outcome of the lawsuit related to Oxtellar XR in February 2016. There is an offsetting reduction in the amount carried as deferred legal fees, as described above.  Amortization expense on intangible assets was approximately $142,000 and $57,000 for the three months ended March 31, 2016 and 2015, respectively.

There were no indicators of impairment identified at March 31, 2016, December 31, 2015 or March 31, 2015.

8.  Accrued Expenses

Accrued expenses are comprised of the following, in thousands, (restated):

	March 31,		December 31,		March 31
	2016		2015		2015
	(unaudited)				(unaudited)
Accrued professional fees	$	9,870	$	10,057	$	3,546
Accrued compensation	5,523		7,519		7,334
Accrued clinical trial and clinical supply costs	2,498		3,677		1,698
Accrued interest expense	393		295		646
Accrued sales and marketing expenses	1,139		434		1,657
Accrued product costs	11		113		131
Other accrued expenses	3,481		3,058		1,470
	$	22,915	$	25,153	$	16,482

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9.  Convertible Senior Secured Notes

The table below summarizes activity related to the Notes from issuance on May 3, 2013 through March 31, 2016, in thousands:

Gross proceeds	$	90,000
Initial value of interest make-whole derivative reported as debt discount	(9,270		)
Conversion option reported as debt discount and APIC	(22,336		)
Conversion of debt to equity - principal	(81,463		)
Conversion of debt to equity - accretion of debt discount and deferred financing costs	25,003
Accretion of debt discount and deferred financing costs	5,151
December 31, 2015 carrying value, restated	7,085
Conversion of debt to equity - principal	(1,962		)
Conversion of debt to equity - accretion of debt discount and deferred financing costs	424
Accretion of debt discount and deferred financing costs	80
March 31, 2016 carrying value, unaudited	$	5,627

During the three month period ended March 31, 2016, approximately $2.0 million of the Notes were presented to the Company for conversion. Accordingly, the Company issued approximately 0.4 million shares of common stock in conversion of the principal amount of the Notes. The Company issued an additional 21,000 shares of common stock in settlement of the interest make-whole provision related to the converted Notes. As a result of the conversions, the Company incurred a loss of approximately $0.4 million on extinguishment of debt during the three months ended March 31, 2016, which is included as a separate component of other income (expense) on the consolidated statement of operations. During the three month period ended March 31, 2015, as a result of approximately $21.4 million in note conversions, the Company incurred a loss of approximately $2.1 million on extinguishment of debt.

10. Summary Stockholders’ Equity

The following summary table provides details related to the activity in certain captions within Stockholders’ Equity for the three month period ended March 31, 2016, in thousands.

	Common Stock		Additional Paid-in Capital
	(unaudited)
Balance, December 31, 2015	$	49	$	263,955
Share-based compensation	—		1,359
Exercise of stock options	—		124
Equity issued on note conversion			2,138
Balance, March 31, 2016	$	49	$	267,576

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11. Share-Based Payments

The Company has adopted the Supernus Pharmaceuticals, Inc. 2012 Equity Incentive Plan (the 2012 Plan), which is stockholder approved, and provides for the grant of stock options and certain other awards, including stock appreciation rights (SAR), restricted and unrestricted stock, stock units, performance awards, cash awards and other awards that are convertible into or otherwise based on the Company’s common stock, to the Company’s key employees, directors, and consultants and advisors. The 2012 Plan is administered by the Company’s Board of Directors and provides for the issuance of up to 4,000,000 shares of the Company’s common stock upon the exercise of stock awards. Option awards are granted with an exercise price equal to the estimated fair value of the Company’s common stock at the grant date. Those option awards generally vest in four annual installments, starting on the first anniversary of the date of grant and have ten year contractual terms. Option awards granted to the directors generally vest over a one year term. Share-based compensation recognized related to the grant of employee and non-employee stock options, SAR, potential Employee Stock Purchase Plan (ESPP) awards and non-vested stock was as follows, in thousands:

	March 31,
	2016		2015
	(unaudited)
Research and development	$	288	$	204
Selling, general and administrative	1,071		698
Total	$	1,359	$	902

The following table summarizes stock option and SAR activity:

	Number of Options		Weighted- Average Exercise Price		Weighted- Average Remaining Contractual Term (in years)
Outstanding, December 31, 2015	2,699,007		$	8.94	7.92
Granted (unaudited)	1,016,750		$	12.98
Exercised (unaudited)	(25,807	)	$	4.79
Forfeited or expired (unaudited)	(1,250	)	$	10.33
Outstanding, March 31, 2016 (unaudited)	3,688,700		$	10.08	8.31
As of December 31, 2015:
Vested and expected to vest	2,654,381		$	8.93	7.90
Exercisable	901,672		$	7.95	6.86
As of March 31, 2016:
Vested and expected to vest (unaudited)	3,605,090		$	10.05	8.28
Exercisable (unaudited)	1,472,911		$	8.36	7.22

12.  Earnings per Share

Basic income per common share is determined by dividing income attributable to common stockholders by the weighted-average number of common shares outstanding during the period, without consideration of common stock equivalents. Diluted income per share is computed by dividing the income attributable to common stockholders by the weighted-average number of common share equivalents outstanding for the period. The treasury stock method is used to determine the dilutive effect of the Company’s stock option grants, SARs, and potential ESPP awards, and the if-converted method is used to determine the dilutive effect of the Company’s Notes.

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The following common stock equivalents were excluded in the calculation of diluted income per share because their effect would be anti-dilutive as applied to the income from continuing operations applicable to common stockholders for the three months ended March 31, 2016 and March 31, 2015:

	Three Months ended March 31,
	2016	2015
	(unaudited)
Shares underlying Convertible Senior Secured Notes	—	6,071,894
Warrants to purchase common stock	—	21,800

The following table sets forth the computation of basic and diluted net income per share for the three months ended March 31, 2016 and March 31, 2015, in thousands, except share and per share amounts, restated:

	Three Months ended March 31,
	2016			2015
	(unaudited)
Numerator, in thousands:
Net income used for calculation of basic EPS	$	4,825		$	738
Interest expense on convertible debt	179			—
Changes in fair value of derivative liabilities	(101		)	—
Loss on extinguishment of debt	382
Loss on extinguishment of outstanding debt, as if converted	(1,229		)	—
Total adjustments	(769		)	—
Net income used for calculation of diluted EPS	$	4,056		$	738
Denominator:
Weighted average shares outstanding, basic	49,240,099			44,563,299
Effect of dilutive potential common shares:
Shares underlying Convertible Senior Secured Notes	1,383,472			—
Shares issuable to settle interest make-whole derivatives	71,537			—
Stock options, stock appreciation rights, and non-vested stock options	456,964			337,999
Total potential dilutive common shares	1,911,973			337,999
Weighted average shares outstanding, diluted	51,152,072			44,901,298
Net income per share, basic	$	0.10		$	0.02
Net income per share, diluted	$	0.08		$	0.02

13. Income Taxes

During the three months ended March 31, 2016, the Company had pre-tax income of $5.0 million. The provision for Federal and state income taxes related to the pre-tax income has been largely offset by the utilization of available net operating loss carryforwards (NOL’s). Accordingly, the Company reduced its valuation allowance against its deferred tax assets and recognized an income tax expense for the jurisdictions that did not have sufficient NOL’s to offset the expected tax expense.

During the three months ended March 31, 2016, the Company recorded $0.2 million of current tax expense primarily related to an increase in our reserve for an uncertain tax position related to the Alternative Minimum Tax.

14. Commitments and Contingencies

The Company has concurrent leases for office and lab space that extend through April 2020. The Company may elect to extend the term of the leases for an additional five-year term. The leases provide for a tenant improvement allowance of approximately $2.1 million in aggregate. During the three months ended March 31, 2016, none of the allowance was utilized. During the three months ended March 31, 2015, none of the allowance was utilized. As of March 31, 2016, $0.5 million remains available for tenant improvements. Rent expense for the leased facilities and leased vehicles for the three months ended March 31, 2016 and March 31, 2015 was approximately, $0.7 million in each period.

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Future minimum lease payments under non-cancelable operating leases as of March 31, 2016 are as follows, in thousands, unaudited:

Year ending December 31:
2016 (remaining)	$	1,027
2017	1,294
2018	1,314
2019	1,341
Thereafter	454
	$	5,430

The Company has obtained exclusive licenses from third parties for proprietary rights to support the product candidates in the Company’s psychiatry portfolio. Under license agreements with Afecta Pharmaceuticals, Inc. (Afecta), the Company has obtained exclusive worldwide rights to selected product candidates, including an exclusive license to SPN-810 (molindone hydrochloride). The Company does not owe any future milestone payments for SPN-810. The Company is obligated to pay royalties in the low-single digits to Afecta based on worldwide net sales of each of these products.

The Company has also entered into a purchase and sale agreement with Rune Healthcare Limited (Rune), where the Company obtained the exclusive worldwide rights to a product concept from Rune. There are no future milestone payments due to Rune under this agreement. If the Company receives approval to market and sell any products based on the Rune product concept for SPN-809 (viloxazine hydrochloride), the Company is obligated to pay royalties to Rune based on net sales worldwide in the low single digits.

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Item 2. Management’s Discussion and Analysis of Financial Condition and Results of Operations (Restated)

Management’s Discussion and Analysis of Financial Condition and Results of Operations is intended to help the reader understand the results of operations and the financial condition of the Company. The interim financial statements included in this report and this Management’s Discussion and Analysis of Financial Condition and Results of Operations should be read in conjunction with our restated audited consolidated financial statements and notes thereto for the year ended December 31, 2015 and the related Management’s Discussion and Analysis of Financial Condition and Results of Operations, both of which are contained in our Annual Report on Form 10-K/A filed with the Securities and Exchange Commission on January 20, 2017.

In addition to historical information, this Quarterly Report on Form 10-Q/A contains forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended, which are intended to be covered by the safe harbors created thereby. These forward-looking statements may include declarations regarding the Company’s belief or current expectations of management, such as statements including the words “budgeted,” “anticipate,” “project,” “estimate,” “expect,” “may,” “believe,” “potential,” and similar statements or expressions, which are intended to be among the statements that are forward-looking statements, as such statements reflect the reality of risk and uncertainty that is inherent in the Company’s business. Actual results may differ materially from those expressed or implied by such forward-looking statements. Readers are cautioned not to place undue reliance on these forward-looking statements, which are made as of the date this report was filed with the Securities and Exchange Commission. Our actual results and the timing of events could differ materially from those discussed in our forward-looking statements as a result of many factors, including those set forth under the “Risk Factors” section of our Annual Report on Form 10-K/A and elsewhere in this report as well as in other reports and documents we file with the Securities and Exchange Commission from time to time. Except as required by law, we undertake no obligation to update any forward-looking statements to reflect events or circumstances occurring after the date of this Quarterly Report on Form 10-Q/A.

Solely for convenience, in this Quarterly Report on Form 10-Q/A the trade names are referred to without the TM symbols and the trademark registrations are referred to without the circled R, but such references should not be construed as any indicator that the Company will not assert, to the fullest extent under applicable law, our rights thereto.

Restatement of Previously Issued Financial Statements

This Management’s Discussion and Analysis of Financial Condition and Results of Operations gives effect to the revision and restatement adjustments made to the previously reported unaudited condensed consolidated financial statements for the three months ended March 31, 2016 and 2015.  For additional information and a detailed discussion of the revision and the restatement, see Note 2. “Restatement of Financial Statements” included in “Part I. Financial Information,” of this Form 10-Q/A.

Overview

We are a specialty pharmaceutical company focused on developing and commercializing products for the treatment of central nervous system (CNS) diseases.

Oxtellar XR and Trokendi XR are the first once-daily extended release oxcarbazepine and topiramate products indicated for patients with epilepsy in the U.S. market. These products differ from immediate release products by offering once-daily dosing and unique pharmacokinetic profiles which we believe can have very positive clinical effects for some patients. We believe a once-daily dosing regimen improves adherence, making it more probable that patients maintain sufficient levels of medication in their bloodstream to protect against seizures. In addition, the unique smooth and steady pharmacokinetic profiles of our once-daily formulations reduce the peak to trough blood level fluctuations that are typically associated with immediate release products, which we believe may result in increased adverse events (AEs), more symptomatic side effects and decreased efficacy.

In addition, we are developing multiple product candidates in psychiatry to address large unmet medical needs and market opportunities. With SPN-810 (molindone hydrochloride), we are developing a product candidate to treat impulsive aggression (IA) in patients who have attention deficit hyperactivity disorder (ADHD). There are currently no approved products indicated for the treatment of IA. We subsequently plan to develop SPN-810 for treatment of IA in other CNS diseases, such as autism, bipolar disorder, schizophrenia, and some forms of dementia. With SPN-812 (viloxazine hydrochloride), we are developing this product candidate to treat patients who have ADHD.

The table below summarizes our current pipeline of novel products and product candidates.

Product	Indication	Status
Oxtellar XR	Epilepsy	Launched
Trokendi XR	Epilepsy*	Launched
SPN-810	Impulsive Aggression**	Phase III
SPN-812	ADHD	Phase IIb
SPN-809	Depression	Phase II ready

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*   Supplemental New Drug Application submitted in August 2015 for treatment in adults for prophylaxis of migraine headache.

** Initial program is in patients with ADHD, with a plan to follow on in other indications, such as IA in patients with autism, bipolar disorder, schizophrenia, and some forms of dementia.

We are continuing to expand our intellectual property portfolio to provide additional protection for our technologies, products, and product candidates. We currently have five U.S. patents issued covering Oxtellar XR and six U.S. patents issued covering Trokendi XR, providing patent protection expiring no earlier than 2027 for each product.

Commercial Products

Trokendi XR

Trokendi XR, the first once-daily extended release topiramate product indicated for patients with epilepsy in the U.S. market, is designed to improve patient adherence over immediate release products, which must be taken multiple times per day.

In August 2015, the United States Food and Drug Administration (FDA) accepted for review the Company’s Supplemental New Drug Application (sNDA) as a Clinical Efficacy Supplement (CES) for Trokendi XR. We requested FDA approval to expand the indication for Trokendi XR to include treatment in adults for prophylaxis of migraine headache. Under the Prescription Drug User Fee Act guidelines, the FDA has set a target date in the second quarter of 2016 to complete its review.

Oxtellar XR

Oxtellar XR is the only once-daily extended release oxcarbazepine product indicated for the treatment of patients with epilepsy in the U.S. as adjunctive therapy.

In a retrospective medical chart review of 200 patients treated with immediate release oxcarbazepine or Oxtellar XR, Oxtellar XR was associated with a significantly lower rate of inpatient hospitalization stays, lower rate of emergency department visits, and a higher rate of compliance. The patient charts were obtained from 17 geographically and clinically diverse sites across the U.S. and included non-academic and academic affiliated practices, general neurology, pediatric neurology, and epilepsy centers.

We expect the number of prescriptions filled for Oxtellar XR and Trokendi XR to continue to increase through the end of 2016 and in subsequent years. Data from Intercontinental Marketing Services (IMS) shows 114,773 prescriptions filled for both drugs during the three months ended March 31, 2016, representing a growth of 49.7% as compared to the 76,690 prescriptions reported for the three months ended March 31, 2015.

We have received several Paragraph IV Notice Letters concerning Oxtellar XR and Trokendi XR from various third-parties. In response to these Paragraph IV notice letters, we have initiated litigation against these third parties alleging infringement of our intellectual property rights. We intend to vigorously defend our intellectual property rights in each of these cases. We anticipate continuing to incur increasing amounts of legal fees and related expenses for these cases as they progress. As of February 8, 2016, the Company announced a court ruling that three patents covering Oxtellar XR were valid and that Actavis infringed two of these three patents by submitting an abbreviated new drug application (ANDA) to the FDA. (See Part II, Item 1—Legal Proceedings in this Quarterly Report on Form 10-Q/A for additional information).

Product Candidates

SPN-810

We are developing SPN-810 as a novel treatment for impulsive aggression in patients who have ADHD. Our Phase III clinical trial (P301) is being conducted under a Special Protocol Assessment (SPA) and SPN-810 has been granted fast-track designation by the FDA. We initiated two Phase III clinical trials in 2015 (P301 and P302) and began dosing patients during the first quarter of 2016. We expect patient enrollment to continue through the end of 2016 and currently project to have data from the trials available by mid-2017.

SPN-812

SPN-812 is being developed as a novel non-stimulant treatment for ADHD. We initiated a Phase IIb dose ranging trial during 2015 and began dosing patients during the first quarter of 2016. We continue to project that we will have data from this Phase IIb trial available by early 2017.

Regarding SPN-812, during the fourth quarter of 2015, final results were received from a single-ascending dose (SAD) and multiple-ascending dose (MAD) study in adult healthy volunteers. These data showed an overwhelmingly favorable adverse event profile for our extended-release formulation at doses that are several multiples of the effective doses used in the immediate release formulation in

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the Phase IIa study. We believe these results could allow us to have a tolerability and safety profile that will not be limiting for our product, and to administer much higher doses than originally expected with potentially higher efficacy. In addition, we recently completed evaluation of the cardiac effects portion of the single ascending and multiple ascending dose study and the data show no clinical significant change in QT interval and other electrocardiograph (ECG) parameters. We believe this further strengthens the potential clinical and safety differentiation of SPN-812.

We expect to incur significant research and development expenses related to the continued development of each of our product candidates, with total cost of approximately $100 million for each of the two programs through FDA approval.

Collaboration Update

Recently, Shire announced positive results of SHP465 Safety and Efficacy Study in Children and Adolescents with ADHD. The study addresses a key U.S. Food and Drug Administration (FDA) requirement, keeping SHP465 on track for resubmission in fourth quarter of 2016 and potential launch in second half of 2017, if it is approved by the FDA. SHP465 was originally developed by Shire Laboratories, the former division of Shire that subsequently became Supernus Pharmaceuticals. Based on the agreement between Supernus and Shire, Shire will pay to Supernus a single digit percentage royalty on net sales of the product.

Critical Accounting Policies and the Use of Estimates

The significant accounting policies and bases of presentation for our consolidated financial statements are described in Note 2 “Summary of Significant Accounting Policies.” The preparation of our consolidated financial statements in accordance with GAAP requires us to make estimates and assumptions that affect the reported amounts of assets, liabilities, revenues, expenses and the disclosure of contingent assets and liabilities. Actual results could differ from those estimates.

We believe the following accounting policies and estimates to be critical:

Revenue Recognition

Revenue from product sales is recognized when: persuasive evidence of an arrangement exists; delivery has occurred and title to the product and associated risk of loss has passed to the customer; the price is fixed or determinable; collection from the customer has been reasonably assured; all performance obligations have been met; and returns and allowances can be reasonably estimated. Product sales are recorded net of estimated rebates, chargebacks, discounts, co-pay assistance and other deductions as well as estimated product returns (collectively, “sales deductions”).

We derive our estimated sales deductions from an analysis of historical levels of deductions specific to each product. In addition, we also consider the impact of anticipated changes in product price, sales trends and changes in managed care coverage and co-pay assistance.

Accounting for Liability related to Sale of Future Royalties

In July 2014, we sold certain royalty rights related to the approved product Orenitram, sold by United Therapeutics, Inc., for $30.0 million to HealthCare Royalty Partners (HC Royalty). Under the relevant accounting guidance, due to a limit on the amount of royalties that HC Royalty can earn under the arrangement, this transaction was accounted for as debt that will be amortized using the effective interest method over the life of the arrangement. We have no obligation to repay any amounts to HC Royalty. In order to record the amortization of the liability, we are required to estimate the total amount of future royalty payments to be received by HC Royalty under the License Agreement. The sum of these amounts less the net proceeds we received of $30.0 million will be recorded as non-cash interest expense over the life of the liability. Consequently, we impute interest on the unamortized portion of the liability and record non-cash interest expense using an imputed effective interest rate. We will periodically assess the expected royalty payments, and to the extent such payments are greater or less than our initial estimate, we will adjust the amortization of the liability and interest rate. As a result of this accounting, even though we do not retain HC Royalty’s share of the royalties, we will continue to record non-cash revenue related to those royalties until the amount of the associated liability and related interest is fully amortized.

Deferred Legal Fees

Deferred legal fees are comprised of costs incurred in connection with defense of patents for Oxtellar XR and Trokendi XR. Amortization of the deferred legal fees will begin upon successful outcome of the on-going litigation. Deferred legal fees will be charged to expense in the event of an unsuccessful outcome of the on-going litigation.

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Research and Development Expenses

Research and development expenditures are expensed as incurred. Research and development costs consist primarily of employee-related expenses, including salaries and benefits; share-based compensation expense; expenses incurred under agreements with clinical research organizations (CROs), investigative sites, consultants and other vendors that conduct the Company’s clinical trials; the cost of acquiring and manufacturing clinical trial materials; the cost of manufacturing materials used in process validation, to the extent that those materials are manufactured prior to receiving regulatory approval for those products and are not expected to be sold commercially; facilities costs that do not have an alternative future use; related depreciation and other allocated expenses; license fees for and milestone payments related to in-licensed products and technologies; and costs associated with animal testing activities and regulatory approvals.

Accrued Clinical Expenses

Clinical trials are inherently complex, often involve multiple service providers, and can include payments made to investigator physicians at study sites. Because billing for services often lags by a substantial amount of time, we often are required to estimate a significant portion of our accrued clinical expenses. This process involves reviewing open contracts and communicating with our subject matter expert personnel and the appropriate service provider personnel to identify services that have been performed on our behalf. We accrue for the estimated but unbilled service performed and the associated cost incurred.

Payments to service providers can either be based on hourly rates for service or based on performance driven milestones.  When accruing clinical expenses, we estimate the time period over which services will be performed during the life of the entire clinical program, the total cost of the program, and the level of effort to be expended in each intervening period. To the maximum extent possible, we work with each service provider to provide an estimate for unbilled services as of the end of the calendar quarter. This includes estimates for payments to site investigators. We work diligently to minimize estimates based solely on company generated calculations. If the service provider underestimates or overestimates the cost associated with a trial or service at any given point in time, adjustments to research and development expenses may be necessary in future periods. Historically, our estimated accrued clinical expenses have closely approximated actual expense incurred.

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Results of Operations

Comparison of the three months ended March 31, 2016 and March 31, 2015

	Three Months ended March 31,
	2016(Restated)			2015(Restated)			Increase/ (decrease)
	(unaudited, in thousands)
Revenues:
Net product sales	$	43,025		$	28,097		14,928
Royalty revenue	1,119			605			514
Licensing revenue	50			36			14
Total revenues	44,194			28,738
Costs and expenses
Cost of product sales	2,035			1,618			417
Research and development	10,562			3,683			6,879
Selling, general and administrative	25,160			19,403			5,757
Total costs and expenses	37,757			24,704
Operating income	6,437			4,034			2,403
Other income (expense)
Interest income and other income, net	331			113			218
Interest expense	(179		)	(381		)	202
Interest expense — non-recourse liability related to sale of future royalties	(1,279		)	(759		)	(520	)
Changes in fair value of derivative liabilities	101			(49		)	150
Loss on extinguishment of debt	(382		)	(2,134		)	1,752
Other expense	(4		)	—			(4	)
Total other expenses	(1,412		)	(3,210		)
Earnings before income taxes	5,025			824
Income tax	200			86			114
Net income	$	4,825		$	738		4,087

Net Product Sales.  The increase in net product sales from 2015 to 2016 is primarily driven by increased prescriptions. Net product sales are based on gross revenue from shipments to distributors, less estimates for discounts, rebates, other sales deductions and returns. The table below lists our net product sales by product comparison, in thousands, unaudited:

	Net Product Sales				Change in Net
	Q1 2016		Q1 2015		Product Sales (%)
Trokendi XR	$	32,320	$	20,926	54.4	%
Oxtellar XR	10,705		7,171		49.3	%
Total	$	43,025	$	28,097	53.1	%

Royalty Revenue (restated). Revenue of $1.1 million and $0.6 million recognized during the three months ended March 31, 2016 and March 31, 2015, respectively, was non-cash revenue generated pursuant to an agreement with HC Royalty.

Research and Development Expense.  Research and development (R&D) expenses during the three months ended March 31, 2016 were $10.6 million as compared to $3.7 million for the three months ended March 31, 2015, an increase of $6.9 million or 186.8%. This increase is primarily due to preclinical and late stage clinical trials for SPN-810 and SPN-812 as well as manufacture of SPN-810 and SPN-812 clinical trial materials. During 2015, we initiated two Phase III trials for SPN-810 and a Phase IIb trial for SPN-812. We expect R&D costs to increase significantly in 2016 and beyond, as we continue to advance these trials and the related development activities for both of these programs.

Selling, General and Administrative Expenses.  Our selling, general and administrative expenses were $25.2 million during the three months ended March 31, 2016 as compared to $19.4 million for the three months ended March 31, 2015, an increase of $5.8 million or

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29.7%. The increase in SG&A expenses is primarily due to the development of promotional material and preparation for the launch of the migraine indication for Trokendi XR in 2016.

Interest Income. During the three months ended March 31, 2016 and March 31, 2015, we recognized $0.3 million and $0.1 million, respectively, of interest income earned on our cash and marketable securities.

Interest Expense.  Interest expense was $0.2 million during the three months ended March 31, 2016 as compared to $0.4 million for the three months ended March 31, 2015. The decrease of $0.2 million was primarily due to a decrease in the principal amount of our outstanding 7.5% Convertible Senior Secured Notes due in 2019 (the Notes) from $14.7 million at March 31, 2015 to $6.6 million at March 31, 2016.

Interest Expense — Non-recourse Liability Related to Sale of Future Royalties.  Interest expense related to our royalty liability was $1.3 million during the three months ended March 31, 2016 as compared to $0.8 million for the three months ended March 31, 2015. The increase of $0.5 million for this non-cash expense item was primarily due to an increase in the expected royalties forecast related to Orenitram.

Changes in Fair Value of Derivative Liability.  During the three months ended March 31, 2016, we recognized a non-cash gain of $0.1 million related to a change in estimated fair value of the interest make-whole derivative liability related to our Notes. This gain is primarily due to the passage of time. During the three months ended March 31, 2015, we recognized a non-cash loss of $49,000 related to a change in estimated fair value of the warrant liability of $143,000, offset by $94,000 of interest make-whole derivative liability related to our Notes. This loss was primarily due to the passage of time.

Loss on Extinguishment of Debt.  During the three months ended March 31, 2016, we recognized a non-cash loss on extinguishment of debt of $0.4 million related to the conversion of $2.0 million of our Notes. During the three months ended March 31, 2015, we recognized a non-cash loss on extinguishment of debt of $2.1 million related to the conversion of $21.4 million of our Notes.

Income Tax.  During the three months ended March 31, 2016, we recorded $0.2 million of current tax expense related primarily to an increase in our reserve for an uncertain tax position related to the Alternative Minimum Tax.

Net Income.  We realized net income of $4.8 million during the three months ended March 31, 2016, compared to a net income of $0.7 million during the three months ended March 31, 2015, an increase of $4.1 million. This change was primarily due to the revenue generated from our two commercial products, Oxtellar XR and Trokendi XR, offset by increased expenses incurred for the late stage studies for our two product candidates, and an increase in marketing expenditures.

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Comparison of the three months ended March 31, 2015 and March 31, 2014

	Three Months ended March 31,
	2015(Restated)			2014			Increase/ (decrease)
	(unaudited, in thousands)
Revenues:
Net product sales	$	28,097		$	8,995		19,102
Royalty revenue	605			—			605
Licensing revenue	36			86			(50	)
Total revenues	28,738			9,081
Costs and expenses
Cost of product sales	1,618			494			1,124
Research and development	3,683			4,482			(799	)
Selling, general and administrative	19,403			17,527			1,876
Total costs and expenses	24,704			22,503
Operating income (loss)	4,034			(13,422		)	17,456
Other income (expense)
Interest income and other income, net	113			102			11
Interest expense	(381		)	(1,207		)	826
Interest expense — non-recourse liability related to sale of future royalties	(759		)	—			(759	)
Changes in fair value of derivative liabilities	(49		)	677			(726	)
Loss on extinguishment of debt	(2,134		)	(1,693		)	(441	)
Total other expenses	(3,210		)	(2,121		)
Earnings before income taxes	824			(15,543		)
Income tax	86			—			86
Net income (loss)	$	738		$	(15,543	)	16,281

Net Product Sales.  Our net product sales of $28.1 million for the three months ended March 31, 2015 are based on $7.2 million of revenue from shipments of Oxtellar XR to distributors, less estimates for discounts, rebates, other sales deductions and returns, and $20.9 million of revenue for Trokendi XR, primarily from shipment to distributors, less estimates for discounts, rebates, other sales deductions and returns.  The increase in net product sales is primarily driven by an increase in underlying prescription growth.

Our net product sales of $9.0 million for the three months ended March 31, 2014 are based on $4.9 million of revenue from shipments of Oxtellar XR to distributors, less estimates for discounts, rebates, other sales deductions and returns, and $4.1 million of revenue on Trokendi XR prescriptions filled at the pharmacy level, according to IMS Health data, during the fourth quarter of 2013, net of sales deductions.

Royalty Revenue (restated). Revenue of $0.6 million recognized during the three months ended March 31, 2015 was non-cash revenue generated pursuant to an agreement with HC Royalty.

Research and Development Expense.  Research and development expenses during the three months ended March 31, 2015 were $3.7 million as compared to $4.5 million for the three months ended March 31, 2014, a decrease of $0.8 million or 17.8%. This decrease is due to the completion of a pharmacokinetics study for SPN-812 in the second quarter of 2014.  During the first quarter of 2015, we were focused on preparing for the late stage studies for SPN-810 and SPN-812. We expect research and development costs to significantly increase throughout 2015.

Selling, General and Administrative Expenses (restated).  Our selling, general and administrative expenses were $19.4 million during the three months ended March 31, 2015 as compared to $17.5 million for the three months ended March 31, 2014, an increase of $1.9 million or 10.7%. This increase was mainly due to the increase in compensation and travel expenses associated with the expansion of our sales force throughout 2014, and an increase in marketing expenses such as sample distribution to support the growth of Oxtellar XR and Trokendi XR.

Interest Expense.  Interest expense was $0.4 million during the three months ended March 31, 2015 as compared to $1.2 million for the three months ended March 31, 2014. The decrease of $0.8 million was primarily due to a decrease in the principal amount of our

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outstanding 7.5% Convertible Senior Secured Notes due in 2019 (the “Notes”) from $40.0 million at March 31, 2014 to $14.7 million at March 31, 2015.

Interest Expense — Non-recourse Liability related to Sale of Future Royalties.  Interest expense related to our royalty liability was $0.8 million during the three months ended March 31, 2015 as compared to zero for the three months ended March 31, 2014. The increase of $0.8 million for this non-cash expense item was primarily due to the fact that this liability existed for all three months of this period in 2015 and did not exist during this three month period in 2014.

Changes in Fair Value of Derivative Liability.  During the three months ended March 31, 2015, we recognized a non-cash loss of $49,000 related to a change in estimated fair value of the warrant liability of $143,000, off set by $94,000 of interest make-whole derivative liability related to our Notes. This loss is primarily due to the passage of time and because our stock price remains above the $5.30 conversion price. We recognized a non-cash credit of $0.7 million associated with the interest make-whole derivative liability during the three months ended March 31, 2014, due primarily to the passage of time.

Loss on Extinguishment of Debt.  During the three months ended March 31, 2015, we recognized a non-cash loss on extinguishment of debt of $2.1 million related to the conversion of $21.4 million of our Notes. During the three months ended March 31, 2014, we recognized a non-cash loss on extinguishment of debt of $1.7 million related to the conversion of $9.5 million of our Notes.

Net Income/ (Loss).  We realized net income of $0.7 million during the three months ended March 31, 2015 as compared to a net loss of $15.5 million during the three months ended March 31, 2014, a change of $16.2 million. This change was primarily due to the revenue generated from our two commercial products, Oxtellar XR and Trokendi XR, partially offset by increased expenses associated with the expansion of our sales force as well as an increase in marketing expenditures associated with ongoing support of Oxtellar XR and Trokendi XR.

Liquidity and Capital Resources at March 31, 2016 (Restated)

We believe with continued increasing levels of net product sales, we will have sufficient resources to finance our operations, including the increased research and development expenses for our clinical program. We expect to incur significantly increased R&D expenses to support the development of SPN-810 and SPN-812 including the late stage trials for SPN-810 and SPN-812.

Our working capital at March 31, 2016 was $38.4 million, a decrease of $10.6 million compared to our working capital of $49.0 million at December 31, 2015. Our long term marketable securities at March 31, 2016 were $68.8 million, an increase of $13.8 million compared to our long term marketable securities of $55.0 million at December 31, 2015.

Our stockholders’ equity increased by $9.1 million during the three month period ended March 31, 2016 primarily as a result of the issuance of shares related to the conversion of our Notes, coupled with net income of $5.0 million.

We expect to continue to incur significant sales and marketing expenses related to the commercial support of Oxtellar XR and Trokendi XR. In addition, we expect to incur substantial expenses related to our research and development efforts, primarily related to development of SPN-810 and SPN-812 as we continue to advance these clinical programs.

In addition to income from operations, we have historically financed our business through the sale of our debt and equity securities. Our most recent financing occurred May 3, 2013, when we issued $90.0 million aggregate principal amount of Notes to qualified institutional buyers, the initial purchasers of the Notes (Initial Purchasers). We issued the Notes under an Indenture, dated May 3, 2013. The Notes provide for 7.50% interest per annum on the principal amount of the Notes, payable semi-annually in arrears on May 1 and November 1 of each year. Interest will accrue on the Notes from and including May 3, 2013 and the Notes will mature on May 1, 2019, unless earlier converted, redeemed or repurchased by the Company. The Notes are secured by a first-priority lien, other than customary permitted liens, on substantially all of our assets, whether now owned or hereafter acquired. In July 2014, we raised $30.0 million non-recourse liability related to sale of future royalties. As of March 31, 2016, holders of the Notes have converted a total of approximately $83.4 million of the Notes. Cumulatively, through March 31, 2016, we issued a total of approximately 15.7 million shares of common stock in conversion of the principal amount of the Notes and issued an additional 2.2 million shares of common stock and paid approximately $1.7 million cash in settlement of the interest make-whole provision related to the converted Notes.

We believe our current working capital and long term marketable securities, along with increased revenues from increasing product sales, will be sufficient to finance the Company. We achieved positive cash flow and profitability from operations in each quarter of 2015. We expect continued profitability in 2016 as we continue to increase sales while also increasing activities and spending to

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advance our clinical product candidates. We expect significant variability from quarter to quarter in our level of profitability primarily due to variability in R&D expenditures for clinical trials and marketing activities.

On December 17, 2014, the SEC declared effective our registration statement on Form S-3.  We have not sold any securities under the registration statement and as of the filing date of this Amended From 10-Q, we are no longer eligible to use the Form S-3 registration statement to sell any securities.

Cash Flows

The following table sets forth the major sources and uses of cash and equivalents for the periods set forth below, in thousands:

	Three Months ended March 31,						Increase/
	2016			2015			(decrease)
	(unaudited) (restated)
Net cash (used in) provided by:
Operating activities	$	(3,142	)	$	(265	)	(2,877	)
Investing activities	(10,650		)	(11,120		)	470
Financing activities	124			147			(23	)
Net decrease in cash and cash equivalents	$	(13,668	)	$	(11,238	)

Operating Activities

Net cash (used in) provided by operating activities is comprised of two components; cash provided by operating income and cash used in changes in working capital. Results for the three months ended March 31, 2016 and March 31, 2015 are summarized below, in thousands:

	Three Months ended March 31,						Increase/
	2016			2015			(decrease)
	(unaudited) (restated)
Cash provided by operating income	$	7,209		$	4,654		2,555
Cash used in changes in working capital	(10,351		)	(4,919		)	(5,432	)
Net cash (used in) provided by operating activities	$	(3,142	)	$	(265	)

The increase in cash used in changes in working capital is primarily driven by increased accounts receivable from increased revenue and decreases in accounts payable and accrued expenses due to timing of payments.

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The changes in certain operating assets and liabilities are, in thousands:

	Three Months ended March 31,
	2016			2015			Explanation of Change
	(unaudited) (restated)
Increase in accounts receivable	$	(4,744	)	$	(2,001	)	Increased sales.
Increase in inventory	(457		)	(261		)	Increase in inventory to support sales growth.
Decrease in prepaid expenses and other assets	260			38			Progress of clinical trials.
Decrease in accounts payable and accrued expenses	(5,783		)	(1,382		)	Increase in expenses, primarily for clinical trial accruals and accrued net sales deductions.
Other	373			(1,313		)
	$	(10,351	)	$	(4,919	)

Investing Activities

We invest excess cash in accordance with our investment policy. Marketable securities consist of investments which mature in four years or less, including United States Treasury and various government agency debt securities, as well as investment grade securities in industrial and financial institutions. Fluctuations in investing activities between periods relate exclusively to the timing of marketable security purchases and the related maturities of these securities.

Net cash used in investing activities for the three months ended March 31, 2016 of $10.7 million related to net purchase of marketable securities of $9.9 million, deferred legal fees of $0.4 million, and property and equipment purchases of $0.3 million. Net cash used in investing activities for the three months ended March 31, 2015 consisted of $11.1 million related to net purchases of marketable securities of $9.2 million, an increase in deferred legal fees of $1.7 million, and property and equipment purchases of $0.2 million.

Financing Activities

Net cash provided by financing activities was $0.1 million for three months ended March 31, 2016, as well as for the three months ended March 31, 2015 and resulted from proceeds received from stock option exercises.

Contractual Obligations and Commitments

The following table summarizes our contractual obligations and commitments as of March 31, 2016 (except as noted below), in thousands, unaudited:

	Less than		1 - 3		3 - 5		Greater than
	1 Year		Years		Years		5 Years		Total
Convertible Senior Secured Notes	$	—	$	—	$	6,575	$	—	$	6,575
Interest on Convertible Notes	493		986		41		—		1,520
Operating leases (1)	1,352		2,617		1,461		—		5,430
Purchase obligations (2)	3,011		—		—		—		3,011
Total (3)	$	4,856	$	3,603	$	8,077	$	—	$	16,536

(1)Our commitments for operating leases relate to our lease of office equipment, fleet vehicles and office and laboratory space as of March 31, 2016.

(2)Relates primarily to agreements and purchase orders with contractors for the conduct of clinical trials, other research and development activities and sales and marketing activities.

(3)This table does not include (a) any milestone payments which may become payable to third parties under license agreements or contractual agreements regarding our clinical trials as the timing and likelihood of such payments are not known, (b) any royalty payments to third parties as the amounts, timing and likelihood of such payments are not known and (c) contracts that are entered into in the ordinary course of business which are not material in the aggregate in any period presented above.

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In addition to the above table, we are contractually obligated to allow all royalty payments earned under a licensing agreement with United Therapeutics Corporation to be paid to HC Royalty.  Although we have recorded a liability of $30.7 million at March 31, 2016 related to this obligation, it is a non-recourse liability for which we have no obligation to make any payments to HC Royalty.  Accordingly, this obligation will have no impact on our liquidity at any time.  As a result, the non-recourse liability has not been included in the table above.

We have obtained exclusive licenses from third parties for proprietary rights to support the product candidates in our psychiatry portfolio. Under license agreements with Afecta, we have an exclusive option to evaluate Afecta’s CNS pipeline and to obtain exclusive worldwide rights to selected product candidates, including an exclusive license to SPN-810. We do not owe any future milestone payments for SPN-810. We will be obligated to pay royalties to Afecta based on net sales worldwide of our product candidates in the low-single digits.

We have also entered into a purchase and sale agreement with Rune, where we obtained the exclusive worldwide rights to a product concept from Rune HealthCare Limited (Rune). There are no future milestone payments owing to Rune under this agreement. If we receive approval to market and sell any products based on the Rune product concept for SPN-809 (viloxazine hydrochloride), we will be obligated to pay royalties to Rune based on net sales worldwide in the low single digits.

Liquidity and Capital Resources at March 31, 2015 (Restated)

Our working capital at March 31, 2015 was $73.9 million, a decrease of $7.7 million compared to our working capital of $81.6 million at December 31, 2014. This decrease was primarily attributable to the purchase of marketable securities and an additional $2.5 million of deferred legal fees.

We expect to continue to incur significant sales and marketing expenses related to the commercial support of Oxtellar XR and Trokendi XR. In addition, we expect to incur substantial expenses related to our research and development efforts, primarily related to development of SPN-810 and SPN-812 as we continue to advance these clinical programs.

In addition to revenues, we have historically financed our business through the sale of our debt and equity securities. On May 3, 2013, we issued $90.0 million aggregate principal amount of Notes to qualified institutional buyers, the initial purchasers of the Notes or the Initial Purchasers. We issued the Notes under an Indenture, dated May 3, 2013. The Notes provide for 7.50% interest per annum on the principal amount of the Notes, payable semi- annually in arrears on May 1 and November 1 of each year. Interest will accrue on the Notes from and including May 3, 2013 and the Notes will mature on May 1, 2019, unless earlier converted, redeemed or repurchased by the Company. The Notes are secured by a first-priority lien, other than customary permitted liens, on substantially all of our and our domestic subsidiaries’ assets, whether now owned or hereafter acquired. In July 2014, we raised $30.0 million through a non-recourse liability related to the sale of future royalties. As of March 31, 2015, holders of the Notes have converted a total of approximately $75.3 million of the Notes. Cumulatively, through March 31, 2015, we issued a total of approximately 14.2 million shares of common stock in conversion of the principal amount of the Notes and issued an additional 2.1 million shares of common stock and paid approximately $1.7 million cash in settlement of the interest make-whole provision related to the converted Notes.

We believe our current working capital and long term marketable securities, along with increased revenues from increasing product sales, will be sufficient to finance the Company. We achieved positive cash flow and profitability from operations during the fourth quarter of 2014 and expect continued profitability for calendar year 2015 as we continue to increase sales while also increasing activities and spending to advance our clinical product candidates.

On December 17, 2014, the SEC declared effective our registration statement on Form S-3.  We have not sold any securities under the registration statement and as of the filing date of this Amended From 10-Q, we are no longer eligible to use the Form S-3 registration statement to sell any securities.

During the period from April 1, 2015 to current, holders of the Notes converted approximately $1.2 million of the Notes and we issued a total of approximately 0.2 million shares of common stock in conversion of the principal amount of the Notes and accrued interest thereon, and issued an additional 20,000 shares of common stock in settlement of the interest make-whole provision related to the converted Notes.

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Cash Flows

The following table sets forth the major sources and uses of cash for the periods set forth below, in thousands:

	Three Months ended March 31,
	2015 (unaudited)  (restated)			2014 (unaudited)			Increase/ (decrease)
Net cash provided by (used in):
Operating activities	$	(265	)	$	(19,104	)	18,839
Investing activities	$	(11,120	)	$	(1,629	)	(9,491	)
Financing activities	$	147		$	5		142
Net increase (decrease) in cash and cash equivalents	$	(11,238	)	$	(20,728	)

Operating Activities

Net cash provided by/used in operating activities is comprised of two components; cash provided by/used in operating income/loss and cash provided by/used in changes in working capital. Results for the three months ended March 31, 2015 and March 31, 2014 are summarized below, in thousands:

	Three Months ended March 31,
	2015 (unaudited)  (restated)			2014 (unaudited)			Increase/ (decrease)
Cash provided by (used in) operating income (loss)	$	4,654		$	(13,058	)	17,712
Cash used by changes in working capital	(4,919		)	(6,046		)	1,127
Net cash provided by (used in) operating activities	$	(265	)	$	(19,104	)

The increase in net cash provided by operating activities is primarily driven by increased revenue generated from the sale of Trokendi XR and Oxtellar XR.

The changes in certain operating assets and liabilities are, in thousands:

	Three Months ended March 31,
	2015			2014			Explanation of Change
	(unaudited)
Increase in accounts receivable	$	(2,001	)	$	(4,671	)	Shipment of additional product to wholesalers.
Increase in inventory	(261		)	(805		)	Buildup of inventory for product sales.
(Decrease) Increase in prepaid expenses and other assets	38			(660		)
Increase in accounts payable and accrued expenses	(1,382		)	(3,656		)	Increase in activity to support both products.
(Increase) decrease in deferred product and licensing revenue	(36		)	4,322			Transition of Trokendi XR revenue recognition to be based on shipments to wholesalers.
Other	(1,277		)	(576		)
	$	(4,919	)	$	(6,046	)

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Investing Activities

Our investing activities are principally driven by cash provided by our financing activities. We invest excess cash in accordance with our investment policy. Marketable securities consist of investments which generally mature in two years or less, including U.S. Treasury and various government agency debt securities, as well as investment grade securities in industrial and financial institutions. Fluctuations in investing activities between periods relate exclusively to the timing of marketable security purchases and the related maturities of these securities.

Net cash used in investing activities for the three months ended March 31, 2015 of $11.1 million related to an increase in deferred legal fees of $1.7 million, property and equipment purchases of $0.2 million, and net purchases of marketable securities of $9.2 million. Net cash used in investing activities for the three months ended March 31, 2014 consisted of $1.6 million related to: the increase in deferred legal fees of $1.0 million; marketable securities holdings increased by $0.3 million, and property and equipment purchases of $0.3 million.

Financing Activities

Net cash provided by financing activities of $0.1 million for the three months ended March 31, 2015 resulted from proceeds received from stock option exercises. Net cash provided by financing activities for the three months ended March 31, 2014 was $5,000, primarily the result of the issuance of common stock related to the exercise of stock options.

Contractual Obligations and Commitments

The following table summarizes our contractual obligations and commitments as of March 31, 2015 (except as noted below), in thousands:

	Less than		1 - 3		3 - 5		Greater than
Contractual Obligations	1 Year		Years		Years		5 Years		Total
Convertible Senior Secured Notes	$	—	$	—	$	14,652	$	—	$	14,652
Interest on Convertible Notes	1,099		2,198		1,190		—		4,487
Operating leases (1)	1,647		2,569		2,668		114		6,998
Purchase obligations (2)	2,749		—		—		—		2,749
Total (3)	$	5,495	$	4,767	$	18,510	$	114	$	28,886

(1)Our commitments for operating leases relate to our lease of office equipment, fleet vehicles and office and laboratory space as of March 31, 2015.

(2)Relates primarily to agreements and purchase orders with contractors for the conduct of clinical trials and other research and development and sales and marketing activities.

(3)This table does not include (a) any milestone payments which may become payable to third parties under license agreements as the timing and likelihood of such payments are not known, (b) any royalty payments to third parties as the amounts, timing and likelihood of such payments are not known and (c) contracts that are entered into in the ordinary course of business which are not material in the aggregate in any period presented above.

In addition to the above table, we are contractually obligated to allow all royalty payments earned under a licensing agreement with United Therapeutics Corporation to be paid to HC Royalty. Although we have recorded a liability of $30.7 million at March 31, 2016 related to this obligation, it is a non-recourse liability for which we have no obligation to make any payments to HC Royalty.  Accordingly, this obligation will have no impact on our liquidity at any time. As a result, these contingent payments to HC Royalty have not been recorded in the table above.

We have obtained exclusive licenses from third parties for proprietary rights to support the product candidates in our psychiatry portfolio. Under license agreements with Afecta Pharmaceuticals, Inc. (Afecta) we have an exclusive option to evaluate Afecta’s CNS pipeline and to obtain exclusive worldwide rights to selected product candidates, including an exclusive license to SPN-810. We do not owe any future milestone payments for SPN-810. We will be obligated to pay royalties to Afecta based on net sales worldwide of our product candidates in the low-single digits. We have also entered into a purchase and sale agreement with Rune, where we obtained the exclusive worldwide rights to a product concept from Rune Healthcare Limited (Rune). There are no future milestone

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payments owing to Rune under this agreement. If we receive approval to market and sell any products based on the Rune product concept for SPN-809, we will be obligated to pay royalties to Rune based on net sales worldwide in the low single digits.

Off-Balance Sheet Arrangements

We do not currently have, nor have we ever had, any relationships with unconsolidated entities or financial partnerships, such entities often referred to as structured finance or special purpose entities, which would have been established for the purpose of facilitating off-balance sheet arrangements or for other contractually narrow or limited purposes. In addition, we do not engage in trading activities involving non-exchange traded contracts.

Recently Issued Accounting Pronouncements

For a discussion of new accounting pronouncements, see Note 3 in the notes to the consolidated financial statements in Part I, Item 1 of this report.

Jumpstart Our Business Startups Act of 2012

The JOBS Act permits an “emerging growth company” such as ours to take advantage of an extended transition period to comply with new or revised accounting standards applicable to public companies. We have chosen to “opt out” of this provision. As a result, we will continue to comply with new or revised accounting standards as required when they are adopted. This decision to opt out of the extended transition period under the JOBS Act is irrevocable.

Item 3. Quantitative and Qualitative Disclosures About Market Risk

The primary objective of our investment activities is to preserve our capital and to fund operations. We also seek to maximize income from our investments without assuming significant interest rate or default risk. Our exposure to market risk is confined to our cash, cash equivalents, marketable securities and long term marketable securities. As of March 31, 2016, we had unrestricted cash, cash equivalents, marketable securities and long term marketable securities of $114.0 million. We do not engage in any hedging activities against changes in interest rates. Because of the short-term maturities of our cash, cash equivalents, marketable securities and long term marketable securities and because we hold these securities to maturity, we do not believe that an increase in market rates would have any significant impact on the realized value of our investments. We do not have any currency or other derivative financial instruments other than the interest make-whole payment associated with our Notes.

We may contract with CROs and investigational sites globally. Currently, we do not have on-going trials outside of the U.S. We may be subject to fluctuations in foreign currency rates in connection with these agreements, primarily with respect to Euro denominated contracts. We do not hedge our foreign currency exchange rate risk. A hypothetical 10% appreciation in Euro exchange rates against the U.S. dollar from prevailing market rates would have decreased our net income by approximately $3,000 for the three months ended March 31, 2016. Conversely, a hypothetical 10% depreciation in Euro exchange rates against the U.S. dollar from prevailing market rates would have increased our net income by approximately $3,000 for the three months ended March 31, 2016. We do not believe that inflation and changing prices over the three months ended March 31, 2016 and March 31, 2015 had a significant impact on our consolidated results of operations.

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Item 4. Controls and Procedures

Evaluation of Disclosure Controls and Procedures

We maintain disclosure controls and procedures as defined in Rules 13a-15(e) and 15d-15(e) of the Securities Exchange Act of 1934, as amended, or the Exchange Act. Our disclosure controls and procedures are designed to provide reasonable assurance that information required to be disclosed by us in the reports we file or submit under the Exchange Act is recorded, processed, summarized and reported within the time periods specified in the Securities and Exchange Commission’s rules and forms, and that such information is accumulated and communicated to our management, including our CEO and our CFO, as appropriate, to allow timely decisions regarding required disclosures.

Our management, including the CEO and CFO, does not expect that our disclosure controls and procedures or our internal control over financial reporting will prevent all error and all fraud. A control system, no matter how well designed and operated, can provide only reasonable, not absolute, assurance that the objectives of the control system are met. Because of the inherent limitations in all control systems, no evaluation of controls can provide absolute assurance that all control issues and instances of fraud, if any, within our company have been detected.

We conducted an evaluation, under the supervision and with the participation of our management, including the CEO and CFO, of the effectiveness of the design and operation of our disclosure controls and procedures pursuant to Rules 13a-15(b) and 15d-15(b) under the Exchange Act. Based on this evaluation, in our Quarterly Report on Form 10-Q for the quarter ended March 31, 2016 filed on May 10, 2016, our CEO and CFO concluded that our disclosure controls and procedures were effective at the reasonable assurance level as of March 31, 2016.

Subsequent to the evaluation made in connection with the Quarterly Report on Form 10-Q in May 2016, and in connection with the preparation and filing of the restatement and this Form 10-Q/A, our management, including the CEO and CFO re-evaluated the effectives of the design and operation of our disclosure controls and procedures. Based on this evaluation our CEO and CFO concluded that our disclosure controls and procedures were not effective as of March 31, 2015 and March 31, 2016 at the reasonable assurance level due to the material weakness described below.

Subsequent to May 10, 2016, management identified a material weakness in internal control over financial reporting. Management’s review revealed that our risk assessment process and our review controls over the accounting for significant, complex, and unusual accounting transactions was deficient, in that these controls were not designed to ensure that sufficient technical accounting expertise was applied to assess and document the appropriate accounting over such transactions.  These control deficiencies resulted in a material misstatement within the Company’s consolidated financial statements, as described in Part I, Item 1; Financial Information — Note 2 to the Consolidated Financial Statements. The presence of these control deficiencies created a reasonable possibility that a material misstatement to the consolidated financial statements would not be prevented or detected on a timely basis. Therefore, we concluded that the deficiencies represented a material weakness in the Company’s internal control over financial reporting and that our internal control over financial reporting was not effective as of March 31, 2016.

Management’s Remediation Initiatives

During 2016, we took action to strengthen our control procedures and risk assessment process regarding the review of the accounting for significant, complex, and unusual transactions. We have engaged, and going forward will continue to engage, expert third party accounting service providers and relevant subject matter experts to supplement the Company’s existing expertise and resources. This will include, amongst other actions, thorough considerations of potential alternative accounting treatment regarding significant, complex, and unusual transactions.

We will continue to devote time and attention to these remediation efforts. As we continue to evaluate and work to improve our controls, management may implement additional measures to enhance the remediation plans described above, and will continue to review and make necessary changes to improve the overall design of our controls.

Changes in Internal Control over Financial Reporting

In the first quarter of 2016, we implemented a new financial accounting system. The software package which was selected has been implemented in numerous publicly held manufacturing and service companies within the U.S. It is supported by a major software provider in the U.S.

The primary impetus for this change was to retire a platform that the Company had outgrown and which lacked much of the additional functionality required to support the Company’s expanded operations. We believe incorporating this additional functionality into an upgraded system will provide a stronger base and enhance our overall control environment. The implementation was not made in response to any significant deficiency or material weakness in our internal control over financial reporting.

Management believes the new system has been successfully implemented and is functioning as required.

Other than the changes described above under “Management’s Remediation Initiatives” and the new financial accounting system implementation, during the three months March 31, 2016, there were no changes in our internal control over financial reporting that materially affected, or are reasonably likely to materially affect, our internal control over financial reporting.

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PART II — OTHER INFORMATION

Item 1. Legal Proceedings

From time to time and in the ordinary course of business, we are subject to various claims, charges and litigation. We may be required to file infringement claims against third parties for the infringement of our patents. We have filed such claims for infringement of the Orange Book patents listed for our products Oxtellar XR and Trokendi XR.

Supernus Pharmaceuticals, Inc. v. Actavis, Inc., et al., C.A. Nos. 13-4740; 14-1981 (RMB)(JS) (D.N.J.)

We received a Paragraph IV Notice Letter against two of our Oxtellar XR Orange Book patents (United States Patent Nos. 7,722,898 and 7,910,131) from generic drug maker Watson Laboratories, Inc.—Florida (WLF) n/k/a Actavis Laboratories FL, Inc. (Actavis Labs FL) on June 26, 2013. On August 7, 2013, we filed a lawsuit against Actavis, Inc., Actavis Labs FL, Actavis Pharma, Inc., Watson Laboratories, Inc., and ANDA, Inc. (collectively Actavis) alleging infringement of United States Patent Nos. 7,722,898 and 7,910,131. We received a second Paragraph IV Notice Letter against a later-issued Oxtellar XR Orange Book Patent (United States Patent No. 8,617,600) on February 20, 2014. On March 28, 2014, we filed a second lawsuit against Actavis alleging infringement of United States Patent No. 8,617,600. We have since listed two additional Orange Book patents: United States Patent Nos. 8,821,930 and 9,119,791. Our United States Patent Nos. 7,722,898, 7,910,131, 8,617,600, 8,821,930, and 9,119,791 generally cover once-a-day oxcarbazepine formulations and methods of treating seizures using those formulations. The FDA Orange Book lists all five of our Oxtellar XR patents as expiring on April 13, 2027.

Both Complaints—filed in the U.S. District Court for the District of New Jersey—allege, inter alia, that Actavis infringed our Oxtellar XR patents by submitting to the FDA an ANDA seeking to market a generic version of Oxtellar XR prior to the expiration of our patents. The two cases were consolidated for all purposes on October 8, 2015.

A seven-day bench trial for the consolidated action involving United States Patent Nos. 7,722,898, 7,910,131, and 8,617,600 was held between November 18 and December 4, 2015. On February 5, 2016, the Court issued an opinion and order finding that: (i) Actavis’s ANDA products infringe United States Patent Nos. 7,722,898 and 7,910,131; (ii) Actavis’s ANDA products do not infringe U.S. Patent No. 8,617,600; and (iii) United States Patent Nos. 7,722,898, 7,910,131, and 8,617,600 are valid.  The Court entered a final judgment on February 18, 2016: (i) enjoining the FDA from approving Actavis’s ANDA before the expiration date of United States Patent Nos. 7,722,898 and 7,910,131; and (ii) enjoining Actavis from commercially manufacturing, using, offering to sell, or selling within the United States, or importing into the United States, Actavis’s ANDA Products until the expiration of United States Patent Nos. 7,722,898 and 7,910,131.  On February 19, 2016, Actavis filed a Notice of Appeal to the United States Court of Appeals for the Federal Circuit.  The appeal (docketed on February 24, 2016) is pending.

Supernus Pharmaceuticals, Inc. v. Actavis, Inc., et al., C.A. Nos. 15-2499 (RMB)(JS) (D.N.J.)

We received a Paragraph IV Notice Letter against United States Patent No. 8,821,930 from Actavis Labs FL on February 21, 2015. On April 7, 2015, we filed a third lawsuit against Actavis alleging infringement of United States Patent No. 8,821,930.

The Complaint—filed in the U.S. District Court for the District of New Jersey—alleges, inter alia, that Actavis infringed United States Patent No. 8,821,930 by submitting to the FDA an ANDA seeking to market a generic version of Oxtellar XR prior to the expiration of United States Patent No. 8,821,930. On April 30, 2015, Actavis answered the Complaint, denying the substantive allegations of that Complaint. Actavis Labs FL also asserted Counterclaims seeking declaratory judgments of non-infringement and invalidity of United States Patent No. 8,821,930. On June 9, 2015, we filed our Reply, denying the substantive allegations of those Counterclaims.

Following an October 7, 2015 Markman hearing, the Court issued a claim construction order for this case on October 9, 2015.  The case is proceeding through fact discovery.

Supernus Pharmaceuticals, Inc. v. TWi Pharmaceuticals, Inc., et al., C.A. Nos. 15-369 (RMB)(JS) (D.N.J.)

We received a Paragraph IV Notice Letter against United States Patent Nos. 7,722,898, 7,910,131, 8,617,600, and 8,821,930 from generic drug maker TWi Pharmaceuticals, Inc. on December 9, 2014. On January 16, 2015, we filed a lawsuit against TWi Pharmaceuticals, Inc. and TWi International LLC (d/b/a TWi Pharmaceuticals USA) (collectively TWi) alleging infringement of United States Patent Nos. 7,722,898, 7,910,131, 8,617,600, and 8,821,930.

The Complaint—filed in the U.S. District Court for the District of New Jersey—alleges, inter alia, that TWi infringed our Oxtellar XR patents by submitting to the FDA an ANDA seeking to market a generic version of Oxtellar XR prior to the expiration of our patents. Filing the Complaint within 45 days of receiving TWi’s Paragraph IV certification notice entitles Supernus to an automatic stay preventing the FDA from approving TWi’s ANDA for 30 months from the date of our receipt of the first Paragraph IV certification

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notice. On February 13, 2015, TWi answered the Complaint and TWi Pharmaceuticals, Inc. and denied the substantive allegations of the complaint.  TWi also asserted Counterclaims seeking declaratory judgments of non-infringement and invalidity of United States Patent Nos. 7,722,898 and 7,910,131. On March 20, 2015, we filed our Reply, denying the substantive allegations of those Counterclaims.

Following an October 7, 2015 Markman hearing, the Court issued a claim construction order for this case on October 9, 2015.  The case is proceeding through fact discovery.

Supernus Pharmaceuticals, Inc. v. Actavis, Inc., et al., C.A. Nos. 15-8342 (RMB)(JS) (D.N.J.)

We received a Paragraph IV Notice Letter against United States Patent No. 9,119,791 from Actavis Labs FL on October 15, 2015. On November 25, 2015, we filed a fourth lawsuit against Actavis alleging infringement of United States Patent No. 9,119,791.

The Complaint—filed in the U.S. District Court for the District of New Jersey—alleges, inter alia, that Actavis infringed United States Patent No. 9,119,791 by submitting to the FDA an ANDA seeking to market a generic version of Oxtellar XR prior to the expiration of United States Patent No. 9,119,791. On January 29, 2016, Actavis answered the Complaint, denying the substantive allegations of that Complaint. Actavis Labs FL also asserted Counterclaims seeking declaratory judgments of non-infringement and invalidity of United States Patent No. 9,119,791.  On March 4, 2016, we filed our Reply, denying the substantive allegations of those Counterclaims.  The court has not yet issued a scheduling order.

Supernus Pharmaceuticals, Inc. v. Actavis, Inc., C.A. No. 14-6102 (SDW)(LDW) (D.N.J.)

We received three Paragraph IV Notice Letters against six Trokendi XR Orange Book patents, namely United States Patent Nos. 8,298,576, 8,298,580, 8,663,683, 8,877,248, 8,889,191, and 8,992,989 from generic drug maker Actavis Laboratories FL, Inc. These patents cover once-a-day topiramate formulations and methods of treating seizures using those formulations. On October 1, 2014, we initiated a lawsuit against Actavis; the lawsuit alleges infringement of the Trokendi XR Orange Book patents. The FDA Orange Book currently lists United States Patent No. 8,298,576 as expiring on April 4, 2028 and United States Patent Nos. 8,298,580, 8,663,683, 8,877,248, 8,889,191, and 8,992,989 as expiring on November 16, 2027.

This action for patent infringement—filed in the U.S. District Court for the District of New Jersey—alleges that Actavis infringed the Trokendi XR patents by, inter alia, submitting to the FDA an ANDA seeking to market a generic version of Trokendi XR prior to the expiration of these patents. Actavis answered these allegations with affirmative defenses and counterclaims of noninfringement and invalidity of the patents in suit. Filing its October 1, 2014 Complaint within 45 days of receiving the first of three Actavis Laboratories FL, Inc. Paragraph IV Notice Letters entitles Supernus to an automatic stay preventing the FDA from approving Actavis’s ANDA for 30 months from the date of our receipt of such Notice Letter.

This case has been consolidated for pretrial purposes with two other actions pending in the District of New Jersey concerning infringement of the Trokendi XR Orange Book patents, those actions being C.A. No. 14-7272 (against Zydus Pharmaceuticals (USA) Inc. and Cadila Healthcare Limited) and C.A. No. 15-326 (against Par Pharmaceutical Companies, Inc. and Par Pharmaceutical, Inc.). The Company has since entered into a settlement agreement with Par (see below). A Rule 16 scheduling conference was held on April 14, 2015. The Court issued a Scheduling Order on May 22, 2015, which was amended several times, most recently on March 7, 2016. The case is proceeding through fact discovery, which ended on May 4, 2016 except for three fact witness depositions and written discovery responses that the parties have agreed would occur after the May 4 deadline.  The case will then proceed through expert discovery which closes on August 26, 2016. The Court’s Amended Scheduling Order also provided that any summary judgment briefing would be completed by September 26, 2016. A Markman hearing took place on February 3, 2016. The Court issued its Markman Opinion and Order on March 9, 2016. The Court adopted Supernus’s definitions of five of the seven disputed terms, and did not adopt any of Actavis’s definitions. No date has been set for trial.

Supernus Pharmaceuticals, Inc. v. Zydus Pharmaceuticals (USA) Inc., C.A. No. 14-7272 (SDW)(LDW) (D.N.J.)

We received three Paragraph IV Notice Letters against six Trokendi XR Orange Book patents, namely United States Patent Nos. 8,298,576, 8,298,580, 8,663,683, 8,877,248, 8,889,191, and 8,992,989 from generic drug maker Zydus Pharmaceuticals (USA) Inc. These patents cover once-a-day topiramate formulations and methods of treating seizures using those formulations. On November 21, 2014, we initiated a lawsuit against Zydus Pharmaceuticals (USA) Inc. and Cadila Healthcare Limited (collectively Zydus); the lawsuit alleges infringement of the Trokendi XR Orange Book patents. The FDA Orange Book currently lists United States Patent No. 8,298,576 as expiring on April 4, 2028 and United States Patent Nos. 8,298,580, 8,663,683, 8,877,248, 8,889,191 and 8,992,989 as expiring on November 16, 2027.

35

This action for patent infringement—filed in the U.S. District Court for the District of New Jersey—alleges that Zydus infringed the Trokendi XR patents by, inter alia, submitting to the FDA an ANDA seeking to market a generic version of Trokendi XR prior to the expiration of these patents. Zydus answered these allegations with affirmative defenses and counterclaims of noninfringement and invalidity of the patents in suit. Filing its November 21, 2014 Complaint within 45 days of receiving the first of three Paragraph IV Notice Letters from Zydus Pharmaceuticals (USA) Inc. entitles Supernus to an automatic stay preventing the FDA from approving Zydus’s ANDA for 30 months from the date of our receipt of such Notice Letter.

This case has been consolidated for pretrial purposes with two other actions pending in the District of New Jersey concerning infringement of the Trokendi XR Orange Book patents, those actions being C.A. No. 14-6102 (against Actavis, Inc., Actavis Laboratories FL, Inc., Actavis plc, Actavis Pharma, Inc., Watson Laboratories, Inc., and ANDA, Inc.) and C.A. No. 15-326 (against Par Pharmaceutical Companies, Inc. and Par Pharmaceutical, Inc.). The Company has since entered into a settlement agreement with Par (see below). A Rule 16 scheduling conference was held on April 14, 2015. The Court issued a Scheduling Order on May 22, 2015, which was amended several times, most recently on March 7, 2016. The case is proceeding through fact discovery, which ended on May 4, 2016 except for three fact witness depositions and written discovery responses that the parties have agreed would occur after the May 4 deadline.  The case will then proceed through expert discovery which closes on August 26, 2016. The Court’s Amended Scheduling Order also provided that any summary judgment briefing would be completed by September 26, 2016. A Markman hearing took place on February 3, 2016. The Court issued its Markman Opinion and Order on March 9, 2016. The Court adopted Supernus’s definitions of five of the seven disputed terms, and did not adopt any of Zydus’s definitions. No date has been set for trial.

Supernus Pharmaceuticals, Inc. v. Par Pharmaceutical Companies, Inc., C.A. No. 15-326 (SDW)(LDW) (D.N.J.)

We received three Paragraph IV Notice Letters against six Trokendi XR Orange Book patents, namely United States Patent Nos. 8,298,576, 8,298,580, 8,663,683, 8,877,248, 8,889,191, and 8,992,989 from generic drug maker Par Pharmaceutical, Inc. These patents cover once-a-day topiramate formulations and methods of treating seizures using those formulations. On January 16, 2015, we initiated a lawsuit against Par; the lawsuit alleges infringement of the Trokendi XR Orange Book patents. The FDA Orange Book currently lists United States Patent No. 8,298,576 as expiring on April 4, 2028 and United States Patent Nos. 8,298,580, 8,663,683, 8,877,248, 8,889,191, and 8,992,989 as expiring on November 16, 2027.

This action for patent infringement—filed in the U.S. District Court for the District of New Jersey—alleges that Par infringed the Trokendi XR patents by, inter alia, submitting to the FDA an ANDA seeking to market a generic version of Trokendi XR prior to the expiration of these patents. Par answered these allegations with affirmative defenses and counterclaims of noninfringement and invalidity of the patents in suit. Filing its January 16, 2015 Complaint within 45 days of receiving the first of three Paragraph IV Notice Letters from Par Pharmaceutical, Inc. entitles Supernus to an automatic stay preventing the FDA from approving Par’s ANDA for 30 months from the date of our receipt of such Notice Letter.

The Company announced on October 15, 2015 that it has entered into a settlement agreement with Par regarding this case. The settlement permits Par to begin selling a generic version of Trokendi XR on April 1, 2025, or earlier under certain circumstances. The agreement is subject to a consent judgment that was entered by the U.S. District Court for the District of New Jersey. In the consent judgment, Par acknowledges that the Orange Book-listed patents for Trokendi XR owned by Supernus, namely United States Patent Nos. 8,298,576, 8,298,580, 8,663,683, 8,877,248, 8,889,191, and 8,992,989, are valid and enforceable with respect to Par’s ANDA product, and would be infringed by Par’s ANDA product. The agreement has been submitted to the applicable governmental agencies.

Item 1A. Risk Factors

Any investment in our business involves a high degree of risk. Before making an investment decision, you should carefully consider the information we include in this Quarterly Report on Form 10-Q/A, including our condensed consolidated financial statements and related notes, and the additional information in the other reports we file with the Securities and Exchange Commission along with the risks described in our Annual Report on Form 10-K/A for the year ended December 31, 2015. These risks may result in material harm to our business and our financial condition and results of operations. In this event, the market price of our common stock may decline and you could lose part or all of your investment.

Item 2. Unregistered Sales of Equity Securities and Use of Proceeds

(a)           Sales of Unregistered Securities.

During the three months ended March 31, 2016, the Company granted options to employees to purchase an aggregate of 1,016,750 shares of common stock at an exercise price of $12.98 per share. The options are exercisable for a period of ten years from the grant date. These issuances were exempt from registration in reliance on Section 4(a)(2) of the Securities Act as transactions not involving any public offering.

36

Item 3. Defaults Upon Senior Securities

None

Item 4. Mine Safety Disclosures

None

Item 5. Other Information

None

Item 6. Exhibits

The following exhibits are filed or furnished as part of this Quarterly Report on Form 10-Q/A:

31.1 Certification of Chief Executive Officer pursuant to Rule 13a-14(a) (filed herewith).

31.2 Certification of Chief Financial Officer pursuant to Rule 13a-14(a) (filed herewith).

32.1 Certification of Chief Executive Officer pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002 (filed herewith).

32.2 Certification of Chief Financial Officer pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002 (filed herewith).

101.INS XBRL Instance Document

101.SCH XBRL Taxonomy Extension Schema Document

101.CAL XBRL Taxonomy Extension Calculation Linkbase Document

101.DEF XBRL Taxonomy Extension Definition Linkbase Document

101.LAB XBRL Taxonomy Extension Label Linkbase Document

101.PRE XBRL Taxonomy Extension Presentation Linkbase Document

37

SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned thereunto duly authorized.

	SUPERNUS PHARMACEUTICALS, INC.
DATED: January 20, 2017		By:	/s/ Jack A. Khattar
		Jack A. Khattar
		President, Secretary and Chief Executive Officer
DATED: January 20, 2017		By:	/s/ Gregory S. Patrick
		Gregory S. Patrick
		Vice President and Chief Financial Officer

38

EXHIBIT INDEX

Number	Description
31.1	Certification of Chief Executive Officer pursuant to Rule 13a-14(a).
31.2	Certification of Chief Financial Officer pursuant to Rule 13a-14(a).
32.1	Certification of Chief Executive Officer pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002.
32.2	Certification of Chief Financial Officer pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002.
101.INS	XBRL Instance Document
101.SCH	XBRL Taxonomy Extension Schema Document
101.CAL	XBRL Taxonomy Extension Calculation Linkbase Document
101.DEF	XBRL Taxonomy Extension Definition Linkbase Document
101.LAB	XBRL Taxonomy Extension Label Linkbase Document
101.PRE	XBRL Taxonomy Extension Presentation Linkbase Document

39

EX-31.1

EXHIBIT 31.1

CERTIFICATION

I, Jack A. Khattar, certify that:

1.             I have reviewed this Quarterly Report on Form 10-Q/A of Supernus Pharmaceuticals, Inc.;

2.             Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period covered by this report;

3.             Based on my knowledge, the financial statements, and other financial information included in this report, fairly present in all material respects the financial condition, results of operations and cash flows of the registrant as of, and for, the periods presented in this report;

4.             The registrant’s other certifying officer and I are responsible for establishing and maintaining disclosure controls and procedures (as defined in Exchange Act Rules 13a-15(e) and 15d-15(e)) and internal control over financial reporting (as defined in Exchange Act Rules 13a-15(f) and 15d-15(f)) for the registrant and have:

(a)           designed such disclosure controls and procedures, or caused such disclosure controls and procedures to be designed under our supervision, to ensure that material information relating to the registrant, including its consolidated subsidiaries, is made known to us by others within those entities, particularly during the period in which this report is being prepared;

(b)           designed such internal control over financial reporting, or caused such internal control over financial reporting to be designed under our supervision, to provide reasonable assurance regarding the reliability of financial reporting and the preparation of financial statements for external purposes in accordance with generally accepted accounting principles;

(c)           evaluated the effectiveness of the registrant’s disclosure controls and procedures and presented in this report our conclusions about the effectiveness of the disclosure controls and procedures, as of the end of the period covered by this report based on such evaluation; and

(d)           disclosed in this report any change in the registrant’s internal control over financial reporting that occurred during the registrant’s most recent fiscal quarter (the registrant’s fourth fiscal quarter in the case of an annual report) that has materially affected, or is reasonably likely to materially affect, the registrant’s internal control over financial reporting; and

5.             The registrant’s other certifying officer and I have disclosed, based on our most recent evaluation of internal control over financial reporting, to the registrant’s auditors and the audit committee of the registrant’s board of directors (or persons performing the equivalent functions):

(a)           all significant deficiencies and material weaknesses in the design or operation of internal control over financial reporting which are reasonably likely to adversely affect the registrant’s ability to record, process, summarize and report financial information; and

(b)           any fraud, whether or not material, that involves management or other employees who have a significant role in the registrant’s internal control over financial reporting.

Date: January 20, 2017	By:	/s/ Jack A. Khattar
		Jack A. Khattar
		President and Chief Executive Officer

EX-31.2

EXHIBIT 31.2

CERTIFICATION

I, Gregory S. Patrick, certify that:

1.             I have reviewed this Quarterly Report on Form 10-Q/A of Supernus Pharmaceuticals, Inc.;

2.             Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period covered by this report;

3.             Based on my knowledge, the financial statements, and other financial information included in this report, fairly present in all material respects the financial condition, results of operations and cash flows of the registrant as of, and for, the periods presented in this report;

4.             The registrant’s other certifying officer and I are responsible for establishing and maintaining disclosure controls and procedures (as defined in Exchange Act Rules 13a-15(e) and 15d-15(e)) and internal control over financial reporting (as defined in Exchange Act Rules 13a-15(f) and 15d-15(f)) for the registrant and have:

(a)           designed such disclosure controls and procedures, or caused such disclosure controls and procedures to be designed under our supervision, to ensure that material information relating to the registrant, including its consolidated subsidiaries, is made known to us by others within those entities, particularly during the period in which this report is being prepared;

(b)           designed such internal control over financial reporting, or caused such internal control over financial reporting to be designed under our supervision, to provide reasonable assurance regarding the reliability of financial reporting and the preparation of financial statements for external purposes in accordance with generally accepted accounting principles;

(c)           evaluated the effectiveness of the registrant’s disclosure controls and procedures and presented in this report our conclusions about the effectiveness of the disclosure controls and procedures, as of the end of the period covered by this report based on such evaluation; and

(d)           disclosed in this report any change in the registrant’s internal control over financial reporting that occurred during the registrant’s most recent fiscal quarter (the registrant’s fourth fiscal quarter in the case of an annual report) that has materially affected, or is reasonably likely to materially affect, the registrant’s internal control over financial reporting; and

5.             The registrant’s other certifying officer and I have disclosed, based on our most recent evaluation of internal control over financial reporting, to the registrant’s auditors and the audit committee of the registrant’s board of directors (or persons performing the equivalent functions):

(a)           all significant deficiencies and material weaknesses in the design or operation of internal control over financial reporting which are reasonably likely to adversely affect the registrant’s ability to record, process, summarize and report financial information; and

(b)           any fraud, whether or not material, that involves management or other employees who have a significant role in the registrant’s internal control over financial reporting.

Date: January 20, 2017	By:	/s/ Gregory S. Patrick
		Gregory S. Patrick
		Vice President and Chief Financial Officer

EX-32.1

EXHIBIT 32.1

SUPERNUS PHARMACEUTICALS, INC.

CERTIFICATION PURSUANT TO

18 U.S.C. sec. 1350,

AS ADOPTED PURSUANT TO

SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002

In connection with the Quarterly Report of Supernus Pharmaceuticals, Inc. (the “Company”) on Form 10-Q/A for the period ended March 31, 2016 as filed with the Securities and Exchange Commission on the date hereof (the “Report”), I, Jack A. Khattar, President and Chief Executive Officer of the Company, certify, pursuant to 18 U.S.C. sec. 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002, that:

(1)           The Report fully complies with the requirements of section 13(a) or 15(d) of the Securities Exchange Act of 1934; and

(2)           The information contained in the Report fairly presents, in all material respects, the financial condition and results of operations of the Company.

Date: January 20, 2017	By:	/s/ Jack A. Khattar
		Jack A. Khattar
		President and Chief Executive Officer

EX-32.2

EXHIBIT 32.2

SUPERNUS PHARMACEUTICALS, INC.

CERTIFICATION PURSUANT TO

18 U.S.C. sec. 1350,

AS ADOPTED PURSUANT TO

SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002

In connection with the Quarterly Report of Supernus Pharmaceuticals, Inc. (the “Company”) on Form 10-Q/A for the period ended March 31, 2016 as filed with the Securities and Exchange Commission on the date hereof (the “Report”), I, Gregory S. Patrick, Vice President and Chief Financial Officer of the Company, certify, pursuant to 18 U.S.C. sec. 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002, that:

(1)           The Report fully complies with the requirements of section 13(a) or 15(d) of the Securities Exchange Act of 1934; and

(2)           The information contained in the Report fairly presents, in all material respects, the financial condition and results of operations of the Company.

Date: January 20, 2017	By:	/s/ Gregory S. Patrick
		Gregory S. Patrick
		Vice President and Chief Financial Officer

XML

Document and Entity Information - shares	3 Months Ended
	Mar. 31, 2016	Jan. 17, 2017
Document and Entity Information
Entity Registrant Name	SUPERNUS PHARMACEUTICALS INC
Entity Central Index Key	0001356576
Document Type	10-Q/A
Document Period End Date	Mar. 31, 2016
Amendment Flag	true
Amendment Description	Unless the context requires otherwise, the words "Supernus," "we," "our," and "the Company" refer to Supernus Pharmaceuticals, Inc. and its subsidiaries. Supernus Pharmaceuticals, Inc. (the Company) is filing this Amendment No. 1 on Form 10-Q/A (the Amended Form 10-Q) to its Quarterly Report on Form 10-Q for the fiscal quarter ended March 31, 2016 (the Original Form 10-Q), which was originally filed with the U.S. Securities and Exchange Commission (SEC) on May 10, 2016 (the Original Filing Date), to reflect the restatement of consolidated financial statements (Restatement) as described below. In this Amended Form 10-Q for the fiscal quarter ended March 31, 2016, we are restating our previously issued and unaudited consolidated financial statements and the related disclosures for the three month periods ended March 31, 2016 and March 31, 2015. As discussed in further detail below and in Note 2 to the accompanying consolidated financial statements, the Restatement is the result of a misapplication in the guidance on accounting for revenue recognition related to the sale of future revenues (as described below). We assessed the impact of this misapplication on our prior interim and annual consolidated financial statements and concluded that the impact was material to these consolidated financial statements. Consequently, we have restated the prior period consolidated financial statements identified above. All amounts in this Amended Form 10-Q affected by the Restatement reflect such amounts as restated. For a more detailed explanation of these matters and resulting restatements, please see Part I, Item 1: Financial Statements – Note 2 to the Consolidated Financial Statements; Part I, Item 2: Management's Discussion and Analysis of Financial Condition and Results of Operations – Restatement of Previously Issued Consolidated Financial Statements; and Part I, Item 4: Controls and Procedures. For the convenience of the reader, this Amended Form 10-Q sets forth the Original Form 10-Q for the three month period ended March 31, 2016 in its entirety, as amended by and to reflect the Restatement and includes certain restated information for the three month period ended March 31, 2015.
Current Fiscal Year End Date	--12-31
Entity Well-known Seasoned Issuer	No
Entity Voluntary Filers	No
Entity Current Reporting Status	No
Entity Filer Category	Large Accelerated Filer
Entity Common Stock, Shares Outstanding		50,121,242
Document Fiscal Year Focus	2016
Document Fiscal Period Focus	Q1

XML

Consolidated Balance Sheets - USD ($) $ in Thousands	Mar. 31, 2016	Dec. 31, 2015	Mar. 31, 2015
Current assets:
Cash and cash equivalents	$ 19,830	$ 33,498	$ 25,158
Marketable securities	25,427	28,692	39,678
Accounts receivable, net	30,651	25,908	19,271
Inventories, net	13,044	12,587	13,702
Prepaid expenses and other current assets	5,003	5,261	3,640
Total current assets	93,955	105,946	101,449
Long term marketable securities	68,790	55,009	27,315
Property and equipment, net	3,866	3,874	2,481
Deferred legal fees	11,444	22,503	7,672
Intangible assets, net	16,108	976	167
Other non-current assets	311	318	321
Total assets	194,474	188,626	139,405
Current liabilities:
Accounts payable	2,646	4,314	859
Accrued sales deductions	28,697	26,794	10,025
Accrued expenses	22,915	25,153	16,482
Non-recourse liability related to sale of future royalties - current portion	1,067	497
Deferred licensing revenue	208	176	143
Total current liabilities	55,533	56,934	27,509
Deferred licensing revenue, net of current portion	1,658	1,390	1,238
Convertible notes, net	5,627	7,085	11,476
Non-recourse liability related to sale of future royalties - long term	29,621	30,031	30,179
Other non-current liabilities	4,391	4,325	2,561
Derivative liabilities	535	854	2,691
Total liabilities	97,365	100,619	75,654
Stockholders' equity:
Common stock, $0.001 par value, 130,000,000 shares authorized at March 31, 2016, December 31, 2015 and March 31, 2015; 49,421,236, 49,004,674 and 47,513,429 shares issued and outstanding at March 31, 2016, December 31, 2015 and March 31, 2015, respectively	49	49	48
Additional paid-in capital	267,576	263,955	252,483
Accumulated other comprehensive income (loss)	168	(488)	(65)
Accumulated deficit	(170,684)	(175,509)	(188,715)
Total stockholders' equity	97,109	88,007	63,751
Total liabilities and stockholders' equity	$ 194,474	$ 188,626	$ 139,405

XML

Consolidated Balance Sheets (Parenthetical) - $ / shares	Mar. 31, 2016	Dec. 31, 2015	Mar. 31, 2015
Consolidated Balance Sheets
Common stock, par value (in dollars per share)	$ 0.001	$ 0.001	$ 0.001
Common stock, shares authorized	130,000,000	130,000,000	130,000,000
Common stock, shares issued	49,421,236	49,004,674	47,513,429
Common stock, shares outstanding	49,421,236	49,004,674	47,513,429

XML

Consolidated Statements of Operations - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2016	Mar. 31, 2015
Revenue
Net product sales	$ 43,025	$ 28,097
Royalty revenues	1,119	605
Licensing revenue	50	36
Total revenue	44,194	28,738
Costs and expenses
Cost of product sales	2,035	1,618
Research and development	10,562	3,683
Selling, general and administrative	25,160	19,403
Total costs and expenses	37,757	24,704
Operating income	6,437	4,034
Other income (expense)
Interest income	331	113
Interest expense	(179)	(381)
Interest expense non-recourse liability related to sale of future royalties	(1,279)	(759)
Changes in fair value of derivative liabilities	101	(49)
Loss on extinguishment of debt	(382)	(2,134)
Other expense	(4)
Total other expense	(1,412)	(3,210)
Earnings before income taxes	5,025	824
Income tax expense	200	86
Net income	$ 4,825	$ 738
Income per common share:
Basic (in dollars per share)	$ 0.10	$ 0.02
Diluted (in dollars per share)	$ 0.08	$ 0.02
Weighted-average number of common shares outstanding:
Basic (in shares)	49,240,099	44,563,299
Diluted (in shares)	51,152,072	44,901,298

XML

Consolidated Statements of Comprehensive Income - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2016	Mar. 31, 2015
Consolidated Statements of Comprehensive Income
Net income	$ 4,825	$ 738
Other comprehensive income:
Unrealized net gain on marketable securities	656	89
Other comprehensive income:	656	89
Comprehensive income	$ 5,481	$ 827

XML

Consolidated Statements of Cash Flows - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2016	Mar. 31, 2015
Cash flows from operating activities
Net income	$ 4,825	$ 738
Adjustments to reconcile net income to net cash (used in) provided by operating activities:
Loss on extinguishment of debt	382	2,134
Change in fair value of derivative liability	(101)	49
Depreciation and amortization	429	214
Non cash interest expense, net/interest income, net	155	463
Non-recourse liability related to sale of future royalties	1,279	759
Non-cash royalty revenue	(1,119)	(605)
Share-based compensation expense	1,359	902
Changes in operating assets and liabilities:
Accounts receivable	(4,744)	(2,001)
Inventories	(457)	(261)
Prepaid expenses and other assets	260	38
Accounts payable	(1,691)	(1,004)
Accrued sales deduction	1,903	1,505
Accrued expenses	(5,995)	(1,883)
Deferred licensing revenue	300	(36)
Other non-current liabilities	73	(1,277)
Net cash (used in) provided by operating activities	(3,142)	(265)
Cash flows from investing activities
Purchases of marketable securities	(17,335)	(17,967)
Sales and maturities of marketable securities	7,400	8,731
Purchases of property and equipment	(279)	(189)
Deferred legal fees	(436)	(1,695)
Net cash used in investing activities	(10,650)	(11,120)
Cash flows from financing activities
Proceeds from issuance of common stock	124	147
Net cash provided by financing activities	124	147
Net change in cash and cash equivalents	(13,668)	(11,238)
Cash and cash equivalents at beginning of period	33,498	36,396
Cash and cash equivalents at end of period	19,830	25,158
Noncash financial activity:
Conversion of convertible notes and interest make-whole	2,138	21,176
Deferred legal fees included in accounts payable and accrued expenses	$ 3,779	$ 3,176

XML

Organization and Business

3 Months Ended

Mar. 31, 2016

Organization and Business

Organization and Business

1.  Organization and Business

Supernus Pharmaceuticals, Inc. (the Company) was incorporated in Delaware on March 30, 2005, and commenced operations on December 22, 2005. The Company is a specialty pharmaceutical company focused on developing and commercializing products for the treatment of central nervous system (CNS) diseases, including neurological and psychiatric disorders. The Company markets two epilepsy products, Oxtellar XR and Trokendi XR, and has several proprietary product candidates in clinical development that address the psychiatry market.

The Company commenced the commercialization of Oxtellar XR and Trokendi XR in 2013.

XML

Restatement of Financial Statements

3 Months Ended

Mar. 31, 2016

Restatement of Financial Statements

Restatement of Financial Statements

2.  Restatement of Financial Statements

In July 2014, the company entered into a royalty monetization transaction and recorded the transaction as revenue. In October 2016, the Company submitted to the U.S. Securities and Exchange Commission’s (the SEC) Office of the Chief Accountant (the OCA) a request for post-accounting review of the royalty monetization transaction from 2014. On November 9, 2016, the OCA completed its review and informed the Company that the royalty monetization transaction should have been recorded as a debt obligation in 2014. As a result, on November 10, 2016, the Company’s Audit Committee concluded that the Company’s financial statements for the years ended December 31, 2014 and December 31, 2015, and the interim quarterly reports in those years beginning with the third quarter of 2014, and the interim quarterly reports for the first and second quarters in 2016 and related reports of the Company’s independent registered public accounting firms thereon, should no longer be relied upon and will be restated.

The Company is restating in this Quarterly Report its financial statements for the three month period ended March 31, 2016 and March 31, 2015. This restatement results in noncash, financial statement corrections and will have no impact on the Company’s current or previously reported cash and marketable securities position or net product sales.

The Company has also made corrections to reflect (i) the recording during the fourth quarter of 2014 of a current tax expense related to an increase in our reserve for an uncertain tax position related to alternative minimum taxes that had been previously recognized in the second quarter of 2015 and (ii) an increase in Selling, General and Administrative Expense in 2014 which is fully offset by a corresponding decrease in Selling, General and Administrative Expense in 2015. This adjustment is the result of the recognition of stock compensation expense over a period of twelve months as opposed to four years related to certain option grants granted in January 2014. Additionally, during the first quarter of 2015, the Company purchased a Certificate of Deposit (CD) that has been continually renewed on a quarterly basis. This CD has 91 days to maturity and the Company incorrectly classified this amount as cash and cash equivalents on the balance sheets at March 31, 2015, June 30, 2015, September 30, 2015 and December 31, 2015. We have corrected the balance sheets in all periods to reflect the reclassification from cash and cash equivalents to current marketable securities. An adjustment was made to the Statement of Cash Flows for the three months ended March 31, 2015 to change cash used in investing activities, with an offset to cash provided by operations for certain accrued legal fees that have been deferred.

The impact of the restatement and other corrections on the condensed Consolidated Balance Sheet, Consolidated Statement of Operations and Consolidated Statement of Cash Flows as of and for the three month periods ended March 31, 2016 and March 31, 2015 is presented below, in thousands except share and per share data.

Three Months Ended March 31, 2016

Consolidated Statement of Operations	As Previously			Restatement			Other
(unaudited)	Reported			Adjustments			Corrections		As Restated
Royalty revenue	$	—		$	1,119		$		$	1,119
Total revenue	43,075			1,119					44,194
Operating income	5,318			1,119					6,437
Interest expense — non-recourse liability related to sale of future royalties	—			(1,279		)			(1,279		)
Total other expense	(133		)	(1,279		)			(1,412		)
Earnings before income taxes	5,185			(160		)			5,025
Income tax expense	198						2		200
Net income	4,987			(160		)	(2	)	4,825

Three Months Ended March 31, 2016

	As Previously			Restatement	Other
Consolidated Statements of Cash Flows (unaudited)	Reported			Adjustments	Corrections		As Restated
Net cash used in investing activities	$	(11,304	)		$	654	$	(10,650	)
Net change in cash and cash equivalents	(14,322		)		654		(13,668		)

As of March 31, 2016

	As Previously			Restatement		Other
Consolidated Balance Sheet (unaudited)	Reported			Adjustments		Corrections			As Restated
Accrued expenses	$	22,573				$	342		$	22,915
Non-recourse liability related to sale of future royalties — current portion	—			1,067					1,067
Total current liabilities	54,124			1,067		342			55,533
Non-recourse liability related to sale of future royalties — long term	—			29,621					29,621
Total liabilities	66,335			30,688		342			97,365
Accumulated deficit	(139,654		)	(30,688	)	(342		)	(170,684		)
Total stockholders’ equity	128,139			(30,688	)	(342		)	97,109

Three Months Ended March 31, 2015

Consolidated Statement of Operations	As Previously			Restatement			Other
(unaudited)	Reported			Adjustments			Corrections		As Restated
Royalty revenue	$	—		$	605		$		$	605
Total revenue	28,133			605					28,738
Selling, general and administrative	19,402						1		19,403
Total costs and expenses	24,703						1		24,704
Operating income	3,430			605			(1	)	4,034
Interest expense — non-recourse liability related to sale of future royalties	—			(759		)			(759		)
Total other expense	(2,451		)	(759		)			(3,210		)
Earnings before income taxes	979			(154		)	(1	)	824
Income tax expense	62						24		86
Net Income	917			(154		)	(25	)	738

Three Months Ended March 31, 2015

	As Previously			Restatement	Other
Consolidated Statements of Cash Flows (unaudited)	Reported			Adjustments	Corrections			As Restated
Net cash provided by (used in) operating activities	$	503			$	(768	)	$	(265	)
Net cash used in investing activities	(11,236		)		116			(11,120		)
Net change in cash and cash equivalents	(10,586		)		(652		)	(11,238		)

As of March 31, 2015

	As Previously			Restatement		Other
Consolidated Balance Sheet (unaudited)	Reported			Adjustments		Corrections			As Restated
Cash and cash equivalents	$	25,810				$	(652	)	$	25,158
Marketable securities	39,026					652			39,678
Accrued expenses	15,828					654			16,482
Total current liabilities	26,855					654			27,509
Non-recourse liability related to sale of future royalties — long term	—			30,179					30,179
Total liabilities	45,053			30,179		422			75,654
Additional paid-in capital	252,341					142			252,483
Accumulated deficit	(157,740		)	(30,179	)	(796		)	(188,715		)
Total stockholders’ equity	94,584			(30,179	)	(654		)	63,751

As of December 31, 2015

	As Previously			Restatement		Other
Consolidated Balance Sheet	Reported			Adjustments		Corrections			As Restated
Cash and cash equivalents	$	34,152				$	(654	)	$	33,498
Marketable securities	28,038					654			28,692
Accrued expenses	24,813					340			25,153
Non-recourse liability related to sale of future royalties — current portion	—			497					497
Total current liabilities	56,097			497		340			56,934
Non-recourse liability related to sale of future royalties — long term	—			30,031					30,031
Total liabilities	69,751			30,528		340			100,619
Accumulated deficit	(144,641		)	(30,528	)	(340		)	(175,509		)
Total stockholders’ equity	118,875			(30,528	)	(340		)	88,007

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Summary of Significant Accounting Policies

3 Months Ended

Mar. 31, 2016

Summary of Significant Accounting Policies

Summary of Significant Accounting Policies

3.  Summary of Significant Accounting Policies

Basis of Presentation

The Company’s consolidated financial statements include the accounts of Supernus Pharmaceuticals, Inc. and Supernus Europe Ltd., collectively referred to herein as “Supernus” or “the Company.” All significant intercompany transactions and balances have been eliminated in consolidation. The Company’s unaudited consolidated financial statements have been prepared in accordance with the requirements of the U.S. Securities and Exchange Commission (SEC) for interim financial information.

As permitted under Generally Accepted Accounting Principles in the United States (U.S. GAAP), certain notes and other information have been omitted from the interim unaudited consolidated financial statements presented in this Quarterly Report on Form 10-Q/A.

Therefore, these financial statements should be read in conjunction with the Company’s Annual Report on Form 10-K/A for the year ended December 31, 2015 filed with the SEC.

In the opinion of management, the consolidated financial statements reflect all adjustments necessary to fairly present the Company’s financial position, results of operations, and cash flows for the periods presented. These adjustments are of a normal recurring nature.  The Company currently operates in one business segment.

The results of operations for the three months ended March 31, 2016 are not necessarily indicative of the Company’s future financial results.

Marketable Securities

Marketable securities consist of investments in U.S. Treasuries, various U.S. governmental agency debt securities, corporate bonds and other fixed income securities. The Company’s investments are classified as available for sale. Such securities are carried at estimated fair value, with any unrealized holding gains or losses reported, net of any tax effects reported, as accumulated other comprehensive income, which is a separate component of stockholders’ equity. Realized gains and losses, and declines in value judged to be other-than-temporary, if any, are included in consolidated results of operations. A decline in the market value of any available for sale security below cost that is deemed to be other-than-temporary results in a reduction in fair value, which is charged to earnings in that period, and a new cost basis for the security is established. Dividend and interest income is recognized when earned. The cost of securities sold is calculated using the specific identification method. The Company places all investments with government, industrial, or financial institutions whose debt is rated as investment grade. The Company classifies all available-for-sale marketable securities with maturities greater than one year from the balance sheet date as non-current assets.

The Company established the Supernus Supplemental Executive Retirement Plan (SERP) for the sole purpose of receiving funds for executives from a previous SERP and providing a continuing deferral program under the Supernus SERP. As of March 31, 2016 and December 31, 2015, the fair value of the SERP was $255,000 and $263,000, respectively. These were held in mutual fund investments. The fair value of these assets is included within other non-current assets on the consolidated balance sheets. A corresponding noncurrent liability is also included in the consolidated balance sheets to reflect the Company’s obligation for the SERP. The Company has not made, and has no plans to make, contributions to the SERP. The securities are restricted in nature and can only be used for purposes of paying benefits under the SERP.

Accounts Receivable, net

Accounts receivable are reported on the consolidated balance sheets at outstanding amounts, less an allowance for doubtful accounts and discounts. The Company extends credit without requiring collateral. The Company writes off uncollectible receivables when the likelihood of collection is remote. The Company evaluates the collectability of accounts receivable on a regular basis. An allowance, when needed, is based upon various factors including the financial condition and payment history of customers, an overall review of collections experience on other accounts, and economic factors or events expected to affect future collections experience. No accounts have been written off as of March 31, 2016 and December 31, 2015. The Company recorded an allowance of approximately $4.0 million and $3.8 million for expected sales discounts as of March 31, 2016 and December 31, 2015, respectively.

Deferred Financing Costs

Deferred financing costs consist of financing costs incurred by the Company in connection with the closing of the Company’s 7.50% Convertible Senior Secured Notes and Secured Notes Payable (see Note 9). The Company amortizes deferred financing costs over the term of the related debt using the effective interest method. When extinguishing debt, the related deferred financing costs are written off.

Revenue Recognition

Revenue from product sales is recognized when persuasive evidence of an arrangement exists; delivery has occurred and title to the product and associated risk of loss has passed to the customer; the price is fixed or determinable; collection from the customer has been reasonably assured; all performance obligations have been met; and returns and allowances can be reasonably estimated. Product sales are recorded net of estimated rebates, chargebacks, discounts, co-pay assistance and other deductions as well as estimated product returns (collectively, “sales deductions”).

Our products are distributed through wholesalers and pharmaceutical distributors. Each of these wholesalers and distributors will take title and ownership to the product upon physical receipt of the product and then distribute our products to pharmacies.

Royalty Revenue

In the third quarter of 2014, the Company received a $30.0 million payment pursuant to a royalty agreement related to the purchase by HC Royalty of certain of the Company’s rights under the agreement with United Therapeutics Corporation related to the commercialization of Orenitram. We have recorded a non-recourse liability related to this transaction and have begun to amortize this amount to recognize royalty revenue as royalties are received by HC Royalty from United Therapeutics. We also recognize non-cash interest expense related to this liability that accrues at an effective interest rate determined based on projections of HC Royalty’s rate of return. We recognized royalty revenue of $1.1 million and $0.6 million for the three months ended March 31, 2016 and 2015, respectively. We recognized interest expense of $1.3 million and $0.8 million for the three months ended March 31, 2016 and 2015, respectively.

Sales Deductions

Allowances for estimated sales deductions are provided for the following:

· Rebates.  Rebates include mandated discounts under the Medicaid Drug Rebate Program, the Medicare coverage gap program, as well as negotiated discounts with commercial healthcare providers. Rebates are amounts owed after the final dispensing of products to a benefit plan participant and are based upon contractual agreements or legal requirements with the public sector (e.g. Medicaid) and with private sector benefit providers. The allowance for rebates is based on statutory and contractual discount rates and expected claimed rebates paid based on a plan provider’s utilization. Rebates are generally invoiced and paid quarterly in arrears so that the accrual balance consists of an estimate of the amount expected to be incurred for the current quarter’s activity, plus an accrual balance for known or estimated prior quarters’ unpaid rebates. If actual future rebates vary from estimates, we may need to adjust balances of such rebates to reflect the actual expenditures of the Company with respect to these programs, which would affect revenue in the period of adjustment.

· Chargebacks.  Chargebacks are discounts that occur when contracted customers purchase directly from an intermediary distributor or wholesaler. Contracted customers, which currently consist primarily of Public Health Service institutions and federal government entities purchasing via the Federal Supply Schedule, generally purchase the product at a discounted price. The distributor or wholesaler, in turn, charges back the difference between the price initially paid by the distributor or wholesaler and the discounted price paid to the distributor or wholesaler by the customer. The allowance for distributor/wholesaler chargebacks is based on known sales to contracted customers.

· Distributor/Wholesaler deductions and discounts.  U.S. specialty distributors and wholesalers are offered various forms of consideration including allowances, service fees and prompt payment discounts as consideration for distributing our products. Distributor allowances and service fees arise from contractual agreements with distributors and are generally a percentage of the purchase price paid by the distributors and wholesalers. Wholesale customers are offered a prompt pay discount for payment within a specified period.

· Co-pay assistance.  Patients who pay in cash or have commercial insurance and meet certain eligibility requirements may receive co-pay assistance from the Company. The intent of this program is to reduce the patient’s out of pocket costs. Liabilities for co-pay assistance are based on actual program participation and estimates of program redemption using data provided by third-party administrators.

· Returns.  Sales of our products are not subject to a general right of return; however, the Company will accept product that is damaged or defective when shipped directly from our warehouse. The Company will accept expired product six months prior and up to 12 months subsequent to its expiry date. Product that has been used to fill patient prescriptions is no longer subject to any right of return.

Milestone Payments

Milestone payments on licensing agreements are recognized as revenue when the collaborative partner acknowledges completion of the milestone and substantive effort (i.e., effort consistent with amount of the milestone) was necessary to achieve the milestone.

Management may recognize revenue contingent upon the achievement of a milestone in its entirety in the period in which the milestone is achieved only if the milestone meets all the criteria to be considered substantive. The Company recorded no milestone revenue during the three months ended March 31, 2016 and March 31, 2015.

Cost of Product Sales

The cost of product sales consists primarily of materials, third-party manufacturing costs, freight and distribution costs, allocation of labor, quality control and assurance, and other manufacturing overhead costs.

Income Taxes

The Company utilizes the asset and liability method of accounting for income taxes. Under this method, deferred tax assets and liabilities are determined based on differences between financial reporting and tax reporting bases of assets and liabilities and are measured using enacted tax rates and laws that are expected to be in effect when the differences are expected to reverse. Valuation allowances are established to reduce deferred tax assets to the amounts expected to be realized.

The Company accounts for uncertain tax positions in its consolidated financial statements when it is more-likely-than-not that the position will be sustained upon examination by the tax authorities. Such tax positions must initially and subsequently be measured as the largest amount of tax benefit that has a greater than 50% likelihood of being realized upon ultimate settlement with the tax authority assuming full knowledge of the position and relevant facts. The Company’s policy is to recognize any interest and penalties related to income taxes in income tax expense.

Recently Issued Accounting Pronouncements

In March 2016, the Financial Accounting Standards Board (FASB) issued Accounting Standards Update (ASU) No. 2016-09, “Compensation- Stock Compensation (Topic 718): Improvements to Employee Share-Based Payment Accounting” (ASU 2016-09). The standard is intended to simplify several areas of accounting for share-based compensation arrangements, including the income tax impact, classification on the statement of cash flows and forfeitures. ASU 2016-09 is effective for fiscal years, and interim periods within those years, beginning after December 15, 2016, and early adoption is permitted. We are currently evaluating the impact that the standard will have on our consolidated financial statements.

In February 2016, the FASB issued ASU No. 2016-02, “Lease (Topic 842)”. The standard requires a lessee to recognize assets and liabilities on the balance sheet for leases with lease terms greater than 12 months. ASU 2016-02 is effective for fiscal years, and interim periods within those years, beginning after December 15, 2018, and early adoption is permitted. We are currently evaluating the impact that the standard will have on our consolidated financial statements.

In April 2015, the FASB issued ASU No. 2015-03, “Simplifying the Presentation of Debt Issuance Costs.” This ASU more closely aligns the treatment of debt issuance costs with debt discounts and premiums and requires debt issuance costs be presented as a direct deduction from the carrying amount of the related debt. The amendments in this ASU are effective for financial statements issued for fiscal years beginning after December 15, 2015 and interim periods within those fiscal years. This guidance has been applied on a retrospective basis and the impact is reflected in the as previously reported column in Note 2. The adoption of ASU No. 2015-03 resulted in a reclassification of deferred financing costs of $232,000 and $104,000 from asset to liability classification on the Company’s consolidated financial statements as of March 31, 2015 and December 31, 2015, respectively.

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Fair Value of Financial Instruments

3 Months Ended

Mar. 31, 2016

Fair Value of Financial Instruments

Fair Value of Financial Instruments

4.  Fair Value of Financial Instruments

The fair value of an asset or liability should represent the price that would be received to sell an asset or paid to transfer a liability in an orderly transaction between market participants. Such transactions to sell an asset or transfer a liability are assumed to occur in the principal or most advantageous market for the asset or liability. Accordingly, fair value is determined based on a hypothetical transaction at the measurement date, considered from the perspective of a market participant rather than from a reporting entity’s perspective.

The Company reports assets and liabilities that are measured at fair value using a three tier or level fair value hierarchy that prioritizes the inputs used to measure fair value. This hierarchy maximizes the use of observable inputs and minimizes the use of unobservable inputs. The three levels of inputs used to measure fair value are as follows:

· Level 1—Inputs are unadjusted quoted prices in active markets for identical assets that the Company has the ability to access at the measurement date.

· Level 2—Inputs are quoted prices for similar assets and liabilities in active markets, quoted prices for identical or similar assets or liabilities in markets that are not active, inputs other than quoted prices that are observable for the asset or liability (interest rates, yield curves, etc.) and inputs that are derived principally from or corroborated by observable market data by correlation or other means (market corroborated inputs).

· Level 3—Unobservable inputs that reflect the Company’s own assumptions, based on the best information available, including the Company’s own data.

In accordance with the fair value hierarchy described above, the following tables show the fair value of the Company’s financial assets and liabilities that are required to be measured at fair value, in thousands:

	Fair Value Measurements at
	March 31, 2016
	(unaudited)
					Significant
	Total Carrying		Quoted Prices		Other		Significant
	Value at		in Active		Observable		Unobservable
	March 31,		Markets		Inputs		Inputs
	2016		(Level 1)		(Level 2)		(Level 3)
Assets:
Cash and cash equivalents	$	19,830	$	19,830	$	—	$	—
Marketable securities	25,427		654		24,773		—
Long term marketable securities	68,790		—		68,790		—
Marketable securities - restricted (SERP)	255		—		255		—
Total assets at fair value	$	114,302	$	20,484	$	93,818	$	—
Liabilities:
Derivative liabilities	$	535	$	—	$	—	$	535

	Fair Value Measurements at
	December 31, 2015
	(restated)
					Significant
	Total Carrying		Quoted Prices		Other		Significant
	Value at		in Active		Observable		Unobservable
	December 31,		Markets		Inputs		Inputs
	2015		(Level 1)		(Level 2)		(Level 3)
Assets:
Cash and cash equivalents	$	33,498	$	33,498	$	—	$	—
Marketable securities	28,692		654		28,038		—
Long term marketable securities	55,009		—		55,009		—
Marketable securities - restricted (SERP)	263		—		263		—
Total assets at fair value	$	117,462	$	34,152	$	83,310	$	—
Liabilities:
Derivative liabilities	$	854	$	—	$	—	$	854

	Fair Value Measurements at
	March 31, 2015
	(unaudited) (restated)
					Significant
	Total Carrying		Quoted Prices		Other		Significant
	Value at		in Active		Observable		Unobservable
	March 31,		Markets		Inputs		Inputs
	2015		(Level 1)		(Level 2)		(Level 3)
Assets:
Cash and cash equivalents	$	25,158	$	25,158	$	—	$	—
Marketable securities	39,678		652		39,026		—
Long term marketable securities	27,315		—		27,315		—
Marketable securities - restricted (SERP)	267		—		267		—
Total assets at fair value	$	92,418	$	25,810	$	66,608	$	—
Liabilities:
Derivative liabilities	$	2,691	$	—	$	—	$	2,691

The fair value of the restricted marketable securities is included within other non-current assets in the consolidated balance sheets.

The Company’s Level 1 assets include cash held with banks, a CD and money market funds.

Level 2 assets include the SERP assets, commercial paper and investment grade corporate bonds and other fixed income securities. Level 2 securities are valued using third-party pricing sources that apply applicable inputs and other relevant data into their models to estimate fair value.

Level 3 liabilities include the estimated fair value of the interest make-whole liability associated with the Company’s 7.50% Convertible Senior Secured Notes due 2019 (the Notes), which are recorded as derivative liabilities.

The fair value of the interest make-whole liability of the Notes was calculated using a binomial-lattice model with the following key assumptions as of March 31, 2016, unaudited:

Volatility	45%
Stock Price as of March 31, 2016	$15.21 per share
Credit Spread	900 bps
Term	1.1 years
Dividend Yield	0.0%

Significant changes to these assumptions could result in increases/decreases to the fair value of the derivative liabilities.

Changes in the fair value of the interest make-whole liability are recognized as a component of Other Income (Expense) in the Consolidated Statements of Operations. The following table presents information about the Company’s Level 3 liabilities as of December 31, 2015 and March 31, 2016 that are included in the Non-Current Liabilities section of the Consolidated Balance Sheets, in thousands:

	Three Months ended
	March 31, 2016
	(unaudited)
Balance at December 31, 2015	$	854
Changes in fair value of derivative liabilities included in earnings	(101		)
Reduction due to conversion of debt to equity	(218		)
Balance at March 31, 2016	$	535

The carrying value, face value and estimated fair value of the Notes was approximately $5.6 million, $6.6 million and $20.0 million, respectively, as of March 31, 2016. The fair value was estimated based on actual trade information as well as quoted prices provided

by bond traders, which would be characterized within Level 2 of the fair value hierarchy. This fair value amount gives recognition to the value of the interest make-whole liability and the value of the conversion option. Upon issuance these were accounted for as derivative liabilities and additional paid-in-capital, respectively.

The carrying amounts of other financial instruments, including accounts receivable, accounts payable and accrued expenses approximate fair value due to their short-term maturities.

Unrestricted marketable securities held by the Company were as follows, in thousands:

At March 31, 2016 (unaudited):

Available for Sale	Amortized Cost		Gross Unrealized Gains	Gross Unrealized Losses		Fair Value
Corporate debt securities	$	94,049	300	(132	)	$	94,217

At December 31, 2015  (restated):

Available for Sale	Amortized Cost		Gross Unrealized Gains	Gross Unrealized Losses		Fair Value
Corporate debt securities	$	84,189	5	(493	)	$	83,701

At March 31, 2015 (unaudited)  (restated):

Available for Sale	Amortized Cost		Gross Unrealized Gains		Gross Unrealized Losses			Fair Value
Corporate debt securities	$	67,058	$	15	$	(80	)	$	66,993

The contractual maturities of the unrestricted available for sale marketable securities held by the Company were as follows, in thousands:

	March 31, 2016
	(unaudited)
Less Than 1 Year	$	25,427
1-5 years	68,790
Greater Than 5 Years	—
Total	$	94,217

The Company has not experienced any other-than-temporary losses on its marketable securities and restricted marketable securities. The cost of securities sold is calculated using the specific identification method.

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Inventories

3 Months Ended

Mar. 31, 2016

Inventories

Inventories

5. Inventories

Inventories consist of the following, in thousands:

	March 31,		December 31,		March 31,
	2016		2015		2015
	(unaudited)				(unaudited)
Raw materials	$	2,371	$	2,887	3,132
Work in process	4,264		3,946		6,328
Finished goods	6,409		5,754		4,242
	$	13,044	$	12,587	$	13,702

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Property and Equipment

3 Months Ended

Mar. 31, 2016

Property and Equipment

Property and Equipment

6.  Property and Equipment

Property and equipment consist of the following, in thousands:

	March 31,			December 31,			March 31,
	2016			2015			2015
	(unaudited)						(unaudited)
Computer equipment	$	1,130		$	1,112		$	932
Software	1,463			307			314
Lab equipment and furniture	5,878			5,667			5,235
Leasehold improvements	2,642			2,642			2,446
Construction in progress	8			1,114			—
	11,121			10,842			8,927
Less accumulated depreciation and amortization	(7,255		)	(6,968		)	(6,446		)
	$	3,866		$	3,874		$	2,481

Depreciation and amortization expense on property and equipment was approximately $287,000 and $156,000 for the three months ended March 31, 2016 and March 31, 2015, respectively.

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Deferred Legal Fees and Intangible Assets

3 Months Ended

Mar. 31, 2016

Deferred Legal Fees and Intangible Assets

Deferred Legal Fees and Intangible Assets

7.  Deferred Legal Fees and Intangible Assets

Deferred legal fees have been incurred in connection with patents for Oxtellar XR and Trokendi XR. As of March 31, 2016 and December 31, 2015, the Company had deferred legal fees of $11.4 million and $22.5 million, respectively.

The following sets forth the gross carrying amount and related accumulated amortization of the intangible asset, in thousands:

		March 31, 2016
		(unaudited)				December 31, 2015
	Weighted-	Gross Carrying		Accumulated		Gross Carrying		Accumulated
	Average Life	Amount		Amortization		Amount		Amortization
Capitalized patent defense costs	9.5	$	16,267	$	159	$	994	$	18

The Company prevailed in a lawsuit related to Oxtellar XR in February 2016, at which time the Company began amortizing the costs associated with that litigation.

The net book value of intangible assets was $16.1 million as of March 31, 2016 and was $1.0 million as of December 31, 2015. The increase in intangible assets reflects the successful outcome of the lawsuit related to Oxtellar XR in February 2016. There is an offsetting reduction in the amount carried as deferred legal fees, as described above.  Amortization expense on intangible assets was approximately $142,000 and $57,000 for the three months ended March 31, 2016 and 2015, respectively.

There were no indicators of impairment identified at March 31, 2016, December 31, 2015 or March 31, 2015.

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Accrued Expenses

3 Months Ended

Mar. 31, 2016

Accrued Expenses

Accrued Expenses

8.  Accrued Expenses

Accrued expenses are comprised of the following, in thousands, (restated):

	March 31,		December 31,		March 31
	2016		2015		2015
	(unaudited)				(unaudited)
Accrued professional fees	$	9,870	$	10,057	$	3,546
Accrued compensation	5,523		7,519		7,334
Accrued clinical trial and clinical supply costs	2,498		3,677		1,698
Accrued interest expense	393		295		646
Accrued sales and marketing expenses	1,139		434		1,657
Accrued product costs	11		113		131
Other accrued expenses	3,481		3,058		1,470
	$	22,915	$	25,153	$	16,482

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Convertible Senior Secured Notes

3 Months Ended

Mar. 31, 2016

Convertible Senior Secured Notes

Convertible Senior Secured Notes

9.  Convertible Senior Secured Notes

The table below summarizes activity related to the Notes from issuance on May 3, 2013 through March 31, 2016, in thousands:

Gross proceeds	$	90,000
Initial value of interest make-whole derivative reported as debt discount	(9,270		)
Conversion option reported as debt discount and APIC	(22,336		)
Conversion of debt to equity - principal	(81,463		)
Conversion of debt to equity - accretion of debt discount and deferred financing costs	25,003
Accretion of debt discount and deferred financing costs	5,151
December 31, 2015 carrying value, restated	7,085
Conversion of debt to equity - principal	(1,962		)
Conversion of debt to equity - accretion of debt discount and deferred financing costs	424
Accretion of debt discount and deferred financing costs	80
March 31, 2016 carrying value, unaudited	$	5,627

During the three month period ended March 31, 2016, approximately $2.0 million of the Notes were presented to the Company for conversion. Accordingly, the Company issued approximately 0.4 million shares of common stock in conversion of the principal amount of the Notes. The Company issued an additional 21,000 shares of common stock in settlement of the interest make-whole provision related to the converted Notes. As a result of the conversions, the Company incurred a loss of approximately $0.4 million on extinguishment of debt during the three months ended March 31, 2016, which is included as a separate component of other income (expense) on the consolidated statement of operations. During the three month period ended March 31, 2015, as a result of approximately $21.4 million in note conversions, the Company incurred a loss of approximately $2.1 million on extinguishment of debt.

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Summary Stockholders' Equity

3 Months Ended

Mar. 31, 2016

Summary Stockholders' Equity

Summary Stockholders' Equity

10. Summary Stockholders’ Equity

The following summary table provides details related to the activity in certain captions within Stockholders’ Equity for the three month period ended March 31, 2016, in thousands.

	Common Stock		Additional Paid-in Capital
	(unaudited)
Balance, December 31, 2015	$	49	$	263,955
Share-based compensation	—		1,359
Exercise of stock options	—		124
Equity issued on note conversion			2,138
Balance, March 31, 2016	$	49	$	267,576

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Share-Based Payments

3 Months Ended

Mar. 31, 2016

Share-Based Payments

Share-Based Payments

11. Share-Based Payments

The Company has adopted the Supernus Pharmaceuticals, Inc. 2012 Equity Incentive Plan (the 2012 Plan), which is stockholder approved, and provides for the grant of stock options and certain other awards, including stock appreciation rights (SAR), restricted and unrestricted stock, stock units, performance awards, cash awards and other awards that are convertible into or otherwise based on the Company’s common stock, to the Company’s key employees, directors, and consultants and advisors. The 2012 Plan is administered by the Company’s Board of Directors and provides for the issuance of up to 4,000,000 shares of the Company’s common stock upon the exercise of stock awards. Option awards are granted with an exercise price equal to the estimated fair value of the Company’s common stock at the grant date. Those option awards generally vest in four annual installments, starting on the first anniversary of the date of grant and have ten year contractual terms. Option awards granted to the directors generally vest over a one year term. Share-based compensation recognized related to the grant of employee and non-employee stock options, SAR, potential Employee Stock Purchase Plan (ESPP) awards and non-vested stock was as follows, in thousands:

	March 31,
	2016		2015
	(unaudited)
Research and development	$	288	$	204
Selling, general and administrative	1,071		698
Total	$	1,359	$	902

The following table summarizes stock option and SAR activity:

	Number of Options		Weighted- Average Exercise Price		Weighted- Average Remaining Contractual Term (in years)
Outstanding, December 31, 2015	2,699,007		$	8.94	7.92
Granted (unaudited)	1,016,750		$	12.98
Exercised (unaudited)	(25,807	)	$	4.79
Forfeited or expired (unaudited)	(1,250	)	$	10.33
Outstanding, March 31, 2016 (unaudited)	3,688,700		$	10.08	8.31
As of December 31, 2015:
Vested and expected to vest	2,654,381		$	8.93	7.90
Exercisable	901,672		$	7.95	6.86
As of March 31, 2016:
Vested and expected to vest (unaudited)	3,605,090		$	10.05	8.28
Exercisable (unaudited)	1,472,911		$	8.36	7.22

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Earnings per Share

3 Months Ended

Mar. 31, 2016

Earnings per Share

Earnings per Share

12.  Earnings per Share

Basic income per common share is determined by dividing income attributable to common stockholders by the weighted-average number of common shares outstanding during the period, without consideration of common stock equivalents. Diluted income per share is computed by dividing the income attributable to common stockholders by the weighted-average number of common share equivalents outstanding for the period. The treasury stock method is used to determine the dilutive effect of the Company’s stock option grants, SARs, and potential ESPP awards, and the if-converted method is used to determine the dilutive effect of the Company’s Notes.

The following common stock equivalents were excluded in the calculation of diluted income per share because their effect would be anti-dilutive as applied to the income from continuing operations applicable to common stockholders for the three months ended March 31, 2016 and March 31, 2015:

	Three Months ended March 31,
	2016	2015
	(unaudited)
Shares underlying Convertible Senior Secured Notes	—	6,071,894
Warrants to purchase common stock	—	21,800

The following table sets forth the computation of basic and diluted net income per share for the three months ended March 31, 2016 and March 31, 2015, in thousands, except share and per share amounts, restated:

	Three Months ended March 31,
	2016			2015
	(unaudited)
Numerator, in thousands:
Net income used for calculation of basic EPS	$	4,825		$	738
Interest expense on convertible debt	179			—
Changes in fair value of derivative liabilities	(101		)	—
Loss on extinguishment of debt	382
Loss on extinguishment of outstanding debt, as if converted	(1,229		)	—
Total adjustments	(769		)	—
Net income used for calculation of diluted EPS	$	4,056		$	738
Denominator:
Weighted average shares outstanding, basic	49,240,099			44,563,299
Effect of dilutive potential common shares:
Shares underlying Convertible Senior Secured Notes	1,383,472			—
Shares issuable to settle interest make-whole derivatives	71,537			—
Stock options, stock appreciation rights, and non-vested stock options	456,964			337,999
Total potential dilutive common shares	1,911,973			337,999
Weighted average shares outstanding, diluted	51,152,072			44,901,298
Net income per share, basic	$	0.10		$	0.02
Net income per share, diluted	$	0.08		$	0.02

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Income Taxes

3 Months Ended

Mar. 31, 2016

Income Taxes

Income Taxes

13. Income Taxes

During the three months ended March 31, 2016, the Company had pre-tax income of $5.0 million. The provision for Federal and state income taxes related to the pre-tax income has been largely offset by the utilization of available net operating loss carryforwards (NOL’s). Accordingly, the Company reduced its valuation allowance against its deferred tax assets and recognized an income tax expense for the jurisdictions that did not have sufficient NOL’s to offset the expected tax expense.

During the three months ended March 31, 2016, the Company recorded $0.2 million of current tax expense primarily related to an increase in our reserve for an uncertain tax position related to the Alternative Minimum Tax.

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Commitments and Contingencies

3 Months Ended

Mar. 31, 2016

Commitments and Contingencies

Commitments and Contingencies

14. Commitments and Contingencies

The Company has concurrent leases for office and lab space that extend through April 2020. The Company may elect to extend the term of the leases for an additional five-year term. The leases provide for a tenant improvement allowance of approximately $2.1 million in aggregate. During the three months ended March 31, 2016, none of the allowance was utilized. During the three months ended March 31, 2015, none of the allowance was utilized. As of March 31, 2016, $0.5 million remains available for tenant improvements. Rent expense for the leased facilities and leased vehicles for the three months ended March 31, 2016 and March 31, 2015 was approximately, $0.7 million in each period.

Future minimum lease payments under non-cancelable operating leases as of March 31, 2016 are as follows, in thousands, unaudited:

Year ending December 31:
2016 (remaining)	$	1,027
2017	1,294
2018	1,314
2019	1,341
Thereafter	454
	$	5,430

The Company has obtained exclusive licenses from third parties for proprietary rights to support the product candidates in the Company’s psychiatry portfolio. Under license agreements with Afecta Pharmaceuticals, Inc. (Afecta), the Company has obtained exclusive worldwide rights to selected product candidates, including an exclusive license to SPN-810 (molindone hydrochloride). The Company does not owe any future milestone payments for SPN-810. The Company is obligated to pay royalties in the low-single digits to Afecta based on worldwide net sales of each of these products.

The Company has also entered into a purchase and sale agreement with Rune Healthcare Limited (Rune), where the Company obtained the exclusive worldwide rights to a product concept from Rune. There are no future milestone payments due to Rune under this agreement. If the Company receives approval to market and sell any products based on the Rune product concept for SPN-809 (viloxazine hydrochloride), the Company is obligated to pay royalties to Rune based on net sales worldwide in the low single digits.

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Summary of Significant Accounting Policies (Policies)

3 Months Ended

Mar. 31, 2016

Summary of Significant Accounting Policies

Basis of Presentation

Basis of Presentation

The Company’s consolidated financial statements include the accounts of Supernus Pharmaceuticals, Inc. and Supernus Europe Ltd., collectively referred to herein as “Supernus” or “the Company.” All significant intercompany transactions and balances have been eliminated in consolidation. The Company’s unaudited consolidated financial statements have been prepared in accordance with the requirements of the U.S. Securities and Exchange Commission (SEC) for interim financial information.

As permitted under Generally Accepted Accounting Principles in the United States (U.S. GAAP), certain notes and other information have been omitted from the interim unaudited consolidated financial statements presented in this Quarterly Report on Form 10-Q/A.

Therefore, these financial statements should be read in conjunction with the Company’s Annual Report on Form 10-K/A for the year ended December 31, 2015 filed with the SEC.

In the opinion of management, the consolidated financial statements reflect all adjustments necessary to fairly present the Company’s financial position, results of operations, and cash flows for the periods presented. These adjustments are of a normal recurring nature.  The Company currently operates in one business segment.

The results of operations for the three months ended March 31, 2016 are not necessarily indicative of the Company’s future financial results.

Marketable Securities

Marketable Securities

Marketable securities consist of investments in U.S. Treasuries, various U.S. governmental agency debt securities, corporate bonds and other fixed income securities. The Company’s investments are classified as available for sale. Such securities are carried at estimated fair value, with any unrealized holding gains or losses reported, net of any tax effects reported, as accumulated other comprehensive income, which is a separate component of stockholders’ equity. Realized gains and losses, and declines in value judged to be other-than-temporary, if any, are included in consolidated results of operations. A decline in the market value of any available for sale security below cost that is deemed to be other-than-temporary results in a reduction in fair value, which is charged to earnings in that period, and a new cost basis for the security is established. Dividend and interest income is recognized when earned. The cost of securities sold is calculated using the specific identification method. The Company places all investments with government, industrial, or financial institutions whose debt is rated as investment grade. The Company classifies all available-for-sale marketable securities with maturities greater than one year from the balance sheet date as non-current assets.

The Company established the Supernus Supplemental Executive Retirement Plan (SERP) for the sole purpose of receiving funds for executives from a previous SERP and providing a continuing deferral program under the Supernus SERP. As of March 31, 2016 and December 31, 2015, the fair value of the SERP was $255,000 and $263,000, respectively. These were held in mutual fund investments. The fair value of these assets is included within other non-current assets on the consolidated balance sheets. A corresponding noncurrent liability is also included in the consolidated balance sheets to reflect the Company’s obligation for the SERP. The Company has not made, and has no plans to make, contributions to the SERP. The securities are restricted in nature and can only be used for purposes of paying benefits under the SERP.

Accounts Receivable, net

Accounts Receivable, net

Accounts receivable are reported on the consolidated balance sheets at outstanding amounts, less an allowance for doubtful accounts and discounts. The Company extends credit without requiring collateral. The Company writes off uncollectible receivables when the likelihood of collection is remote. The Company evaluates the collectability of accounts receivable on a regular basis. An allowance, when needed, is based upon various factors including the financial condition and payment history of customers, an overall review of collections experience on other accounts, and economic factors or events expected to affect future collections experience. No accounts have been written off as of March 31, 2016 and December 31, 2015. The Company recorded an allowance of approximately $4.0 million and $3.8 million for expected sales discounts as of March 31, 2016 and December 31, 2015, respectively.

Deferred Financing Costs

Deferred Financing Costs

Deferred financing costs consist of financing costs incurred by the Company in connection with the closing of the Company’s 7.50% Convertible Senior Secured Notes and Secured Notes Payable (see Note 9). The Company amortizes deferred financing costs over the term of the related debt using the effective interest method. When extinguishing debt, the related deferred financing costs are written off.

Revenue Recognition

Revenue Recognition

Revenue from product sales is recognized when persuasive evidence of an arrangement exists; delivery has occurred and title to the product and associated risk of loss has passed to the customer; the price is fixed or determinable; collection from the customer has been reasonably assured; all performance obligations have been met; and returns and allowances can be reasonably estimated. Product sales are recorded net of estimated rebates, chargebacks, discounts, co-pay assistance and other deductions as well as estimated product returns (collectively, “sales deductions”).

Our products are distributed through wholesalers and pharmaceutical distributors. Each of these wholesalers and distributors will take title and ownership to the product upon physical receipt of the product and then distribute our products to pharmacies.

Royalty Revenue

In the third quarter of 2014, the Company received a $30.0 million payment pursuant to a royalty agreement related to the purchase by HC Royalty of certain of the Company’s rights under the agreement with United Therapeutics Corporation related to the commercialization of Orenitram. We have recorded a non-recourse liability related to this transaction and have begun to amortize this amount to recognize royalty revenue as royalties are received by HC Royalty from United Therapeutics. We also recognize non-cash interest expense related to this liability that accrues at an effective interest rate determined based on projections of HC Royalty’s rate of return. We recognized royalty revenue of $1.1 million and $0.6 million for the three months ended March 31, 2016 and 2015, respectively. We recognized interest expense of $1.3 million and $0.8 million for the three months ended March 31, 2016 and 2015, respectively.

Sales Deductions

Allowances for estimated sales deductions are provided for the following:

· Rebates.  Rebates include mandated discounts under the Medicaid Drug Rebate Program, the Medicare coverage gap program, as well as negotiated discounts with commercial healthcare providers. Rebates are amounts owed after the final dispensing of products to a benefit plan participant and are based upon contractual agreements or legal requirements with the public sector (e.g. Medicaid) and with private sector benefit providers. The allowance for rebates is based on statutory and contractual discount rates and expected claimed rebates paid based on a plan provider’s utilization. Rebates are generally invoiced and paid quarterly in arrears so that the accrual balance consists of an estimate of the amount expected to be incurred for the current quarter’s activity, plus an accrual balance for known or estimated prior quarters’ unpaid rebates. If actual future rebates vary from estimates, we may need to adjust balances of such rebates to reflect the actual expenditures of the Company with respect to these programs, which would affect revenue in the period of adjustment.

· Chargebacks.  Chargebacks are discounts that occur when contracted customers purchase directly from an intermediary distributor or wholesaler. Contracted customers, which currently consist primarily of Public Health Service institutions and federal government entities purchasing via the Federal Supply Schedule, generally purchase the product at a discounted price. The distributor or wholesaler, in turn, charges back the difference between the price initially paid by the distributor or wholesaler and the discounted price paid to the distributor or wholesaler by the customer. The allowance for distributor/wholesaler chargebacks is based on known sales to contracted customers.

· Distributor/Wholesaler deductions and discounts.  U.S. specialty distributors and wholesalers are offered various forms of consideration including allowances, service fees and prompt payment discounts as consideration for distributing our products. Distributor allowances and service fees arise from contractual agreements with distributors and are generally a percentage of the purchase price paid by the distributors and wholesalers. Wholesale customers are offered a prompt pay discount for payment within a specified period.

· Co-pay assistance.  Patients who pay in cash or have commercial insurance and meet certain eligibility requirements may receive co-pay assistance from the Company. The intent of this program is to reduce the patient’s out of pocket costs. Liabilities for co-pay assistance are based on actual program participation and estimates of program redemption using data provided by third-party administrators.

· Returns.  Sales of our products are not subject to a general right of return; however, the Company will accept product that is damaged or defective when shipped directly from our warehouse. The Company will accept expired product six months prior and up to 12 months subsequent to its expiry date. Product that has been used to fill patient prescriptions is no longer subject to any right of return.

Milestone Payments

Milestone payments on licensing agreements are recognized as revenue when the collaborative partner acknowledges completion of the milestone and substantive effort (i.e., effort consistent with amount of the milestone) was necessary to achieve the milestone.

Management may recognize revenue contingent upon the achievement of a milestone in its entirety in the period in which the milestone is achieved only if the milestone meets all the criteria to be considered substantive. The Company recorded no milestone revenue during the three months ended March 31, 2016 and March 31, 2015.

Cost of Product Sales

Cost of Product Sales

The cost of product sales consists primarily of materials, third-party manufacturing costs, freight and distribution costs, allocation of labor, quality control and assurance, and other manufacturing overhead costs.

Income Taxes

Income Taxes

The Company utilizes the asset and liability method of accounting for income taxes. Under this method, deferred tax assets and liabilities are determined based on differences between financial reporting and tax reporting bases of assets and liabilities and are measured using enacted tax rates and laws that are expected to be in effect when the differences are expected to reverse. Valuation allowances are established to reduce deferred tax assets to the amounts expected to be realized.

The Company accounts for uncertain tax positions in its consolidated financial statements when it is more-likely-than-not that the position will be sustained upon examination by the tax authorities. Such tax positions must initially and subsequently be measured as the largest amount of tax benefit that has a greater than 50% likelihood of being realized upon ultimate settlement with the tax authority assuming full knowledge of the position and relevant facts. The Company’s policy is to recognize any interest and penalties related to income taxes in income tax expense.

Recently Issued Accounting Pronouncements

Recently Issued Accounting Pronouncements

In March 2016, the Financial Accounting Standards Board (FASB) issued Accounting Standards Update (ASU) No. 2016-09, “Compensation- Stock Compensation (Topic 718): Improvements to Employee Share-Based Payment Accounting” (ASU 2016-09). The standard is intended to simplify several areas of accounting for share-based compensation arrangements, including the income tax impact, classification on the statement of cash flows and forfeitures. ASU 2016-09 is effective for fiscal years, and interim periods within those years, beginning after December 15, 2016, and early adoption is permitted. We are currently evaluating the impact that the standard will have on our consolidated financial statements.

In February 2016, the FASB issued ASU No. 2016-02, “Lease (Topic 842)”. The standard requires a lessee to recognize assets and liabilities on the balance sheet for leases with lease terms greater than 12 months. ASU 2016-02 is effective for fiscal years, and interim periods within those years, beginning after December 15, 2018, and early adoption is permitted. We are currently evaluating the impact that the standard will have on our consolidated financial statements.

In April 2015, the FASB issued ASU No. 2015-03, “Simplifying the Presentation of Debt Issuance Costs.” This ASU more closely aligns the treatment of debt issuance costs with debt discounts and premiums and requires debt issuance costs be presented as a direct deduction from the carrying amount of the related debt. The amendments in this ASU are effective for financial statements issued for fiscal years beginning after December 15, 2015 and interim periods within those fiscal years. This guidance has been applied on a retrospective basis and the impact is reflected in the as previously reported column in Note 2. The adoption of ASU No. 2015-03 resulted in a reclassification of deferred financing costs of $232,000 and $104,000 from asset to liability classification on the Company’s consolidated financial statements as of March 31, 2015 and December 31, 2015, respectively.

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Restatement of Financial Statements (Tables)

3 Months Ended

Mar. 31, 2016

Restatement of Financial Statements

Schedule of restatement on the condensed consolidated balance sheet, consolidated statement of operations and consolidated statement of cash flows

The impact of the restatement and other corrections on the condensed Consolidated Balance Sheet, Consolidated Statement of Operations and Consolidated Statement of Cash Flows as of and for the three month periods ended March 31, 2016 and March 31, 2015 is presented below, in thousands except share and per share data.

Three Months Ended March 31, 2016

Consolidated Statement of Operations	As Previously			Restatement			Other
(unaudited)	Reported			Adjustments			Corrections		As Restated
Royalty revenue	$	—		$	1,119		$		$	1,119
Total revenue	43,075			1,119					44,194
Operating income	5,318			1,119					6,437
Interest expense — non-recourse liability related to sale of future royalties	—			(1,279		)			(1,279		)
Total other expense	(133		)	(1,279		)			(1,412		)
Earnings before income taxes	5,185			(160		)			5,025
Income tax expense	198						2		200
Net income	4,987			(160		)	(2	)	4,825

Three Months Ended March 31, 2016

	As Previously			Restatement	Other
Consolidated Statements of Cash Flows (unaudited)	Reported			Adjustments	Corrections		As Restated
Net cash used in investing activities	$	(11,304	)		$	654	$	(10,650	)
Net change in cash and cash equivalents	(14,322		)		654		(13,668		)

As of March 31, 2016

	As Previously			Restatement		Other
Consolidated Balance Sheet (unaudited)	Reported			Adjustments		Corrections			As Restated
Accrued expenses	$	22,573				$	342		$	22,915
Non-recourse liability related to sale of future royalties — current portion	—			1,067					1,067
Total current liabilities	54,124			1,067		342			55,533
Non-recourse liability related to sale of future royalties — long term	—			29,621					29,621
Total liabilities	66,335			30,688		342			97,365
Accumulated deficit	(139,654		)	(30,688	)	(342		)	(170,684		)
Total stockholders’ equity	128,139			(30,688	)	(342		)	97,109

Three Months Ended March 31, 2015

Consolidated Statement of Operations	As Previously			Restatement			Other
(unaudited)	Reported			Adjustments			Corrections		As Restated
Royalty revenue	$	—		$	605		$		$	605
Total revenue	28,133			605					28,738
Selling, general and administrative	19,402						1		19,403
Total costs and expenses	24,703						1		24,704
Operating income	3,430			605			(1	)	4,034
Interest expense — non-recourse liability related to sale of future royalties	—			(759		)			(759		)
Total other expense	(2,451		)	(759		)			(3,210		)
Earnings before income taxes	979			(154		)	(1	)	824
Income tax expense	62						24		86
Net Income	917			(154		)	(25	)	738

Three Months Ended March 31, 2015

	As Previously			Restatement	Other
Consolidated Statements of Cash Flows (unaudited)	Reported			Adjustments	Corrections			As Restated
Net cash provided by (used in) operating activities	$	503			$	(768	)	$	(265	)
Net cash used in investing activities	(11,236		)		116			(11,120		)
Net change in cash and cash equivalents	(10,586		)		(652		)	(11,238		)

As of March 31, 2015

	As Previously			Restatement		Other
Consolidated Balance Sheet (unaudited)	Reported			Adjustments		Corrections			As Restated
Cash and cash equivalents	$	25,810				$	(652	)	$	25,158
Marketable securities	39,026					652			39,678
Accrued expenses	15,828					654			16,482
Total current liabilities	26,855					654			27,509
Non-recourse liability related to sale of future royalties — long term	—			30,179					30,179
Total liabilities	45,053			30,179		422			75,654
Additional paid-in capital	252,341					142			252,483
Accumulated deficit	(157,740		)	(30,179	)	(796		)	(188,715		)
Total stockholders’ equity	94,584			(30,179	)	(654		)	63,751

As of December 31, 2015

	As Previously			Restatement		Other
Consolidated Balance Sheet	Reported			Adjustments		Corrections			As Restated
Cash and cash equivalents	$	34,152				$	(654	)	$	33,498
Marketable securities	28,038					654			28,692
Accrued expenses	24,813					340			25,153
Non-recourse liability related to sale of future royalties — current portion	—			497					497
Total current liabilities	56,097			497		340			56,934
Non-recourse liability related to sale of future royalties — long term	—			30,031					30,031
Total liabilities	69,751			30,528		340			100,619
Accumulated deficit	(144,641		)	(30,528	)	(340		)	(175,509		)
Total stockholders’ equity	118,875			(30,528	)	(340		)	88,007

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Fair Value of Financial Instruments (Tables)

3 Months Ended

Mar. 31, 2016

Fair Value of Financial Instruments

Schedule of fair value of the financial assets and liabilities

In accordance with the fair value hierarchy described above, the following tables show the fair value of the Company’s financial assets and liabilities that are required to be measured at fair value, in thousands:

	Fair Value Measurements at
	March 31, 2016
	(unaudited)
					Significant
	Total Carrying		Quoted Prices		Other		Significant
	Value at		in Active		Observable		Unobservable
	March 31,		Markets		Inputs		Inputs
	2016		(Level 1)		(Level 2)		(Level 3)
Assets:
Cash and cash equivalents	$	19,830	$	19,830	$	—	$	—
Marketable securities	25,427		654		24,773		—
Long term marketable securities	68,790		—		68,790		—
Marketable securities - restricted (SERP)	255		—		255		—
Total assets at fair value	$	114,302	$	20,484	$	93,818	$	—
Liabilities:
Derivative liabilities	$	535	$	—	$	—	$	535

	Fair Value Measurements at
	December 31, 2015
	(restated)
					Significant
	Total Carrying		Quoted Prices		Other		Significant
	Value at		in Active		Observable		Unobservable
	December 31,		Markets		Inputs		Inputs
	2015		(Level 1)		(Level 2)		(Level 3)
Assets:
Cash and cash equivalents	$	33,498	$	33,498	$	—	$	—
Marketable securities	28,692		654		28,038		—
Long term marketable securities	55,009		—		55,009		—
Marketable securities - restricted (SERP)	263		—		263		—
Total assets at fair value	$	117,462	$	34,152	$	83,310	$	—
Liabilities:
Derivative liabilities	$	854	$	—	$	—	$	854

	Fair Value Measurements at
	March 31, 2015
	(unaudited) (restated)
					Significant
	Total Carrying		Quoted Prices		Other		Significant
	Value at		in Active		Observable		Unobservable
	March 31,		Markets		Inputs		Inputs
	2015		(Level 1)		(Level 2)		(Level 3)
Assets:
Cash and cash equivalents	$	25,158	$	25,158	$	—	$	—
Marketable securities	39,678		652		39,026		—
Long term marketable securities	27,315		—		27,315		—
Marketable securities - restricted (SERP)	267		—		267		—
Total assets at fair value	$	92,418	$	25,810	$	66,608	$	—
Liabilities:
Derivative liabilities	$	2,691	$	—	$	—	$	2,691

Schedule of assumptions used to calculate fair value of make-whole liability

Volatility	45%
Stock Price as of March 31, 2016	$15.21 per share
Credit Spread	900 bps
Term	1.1 years
Dividend Yield	0.0%

Schedule of Level 3 liabilities included in Non-current Liabilities on the Balance Sheet

The following table presents information about the Company’s Level 3 liabilities as of December 31, 2015 and March 31, 2016 that are included in the Non-Current Liabilities section of the Consolidated Balance Sheets, in thousands:

	Three Months ended
	March 31, 2016
	(unaudited)
Balance at December 31, 2015	$	854
Changes in fair value of derivative liabilities included in earnings	(101		)
Reduction due to conversion of debt to equity	(218		)
Balance at March 31, 2016	$	535

Schedule of unrestricted marketable securities

Unrestricted marketable securities held by the Company were as follows, in thousands:

At March 31, 2016 (unaudited):

Available for Sale	Amortized Cost		Gross Unrealized Gains	Gross Unrealized Losses		Fair Value
Corporate debt securities	$	94,049	300	(132	)	$	94,217

At December 31, 2015  (restated):

Available for Sale	Amortized Cost		Gross Unrealized Gains	Gross Unrealized Losses		Fair Value
Corporate debt securities	$	84,189	5	(493	)	$	83,701

At March 31, 2015 (unaudited)  (restated):

Available for Sale	Amortized Cost		Gross Unrealized Gains		Gross Unrealized Losses			Fair Value
Corporate debt securities	$	67,058	$	15	$	(80	)	$	66,993

Schedule of contractual maturities of the unrestricted marketable securities held

The contractual maturities of the unrestricted available for sale marketable securities held by the Company were as follows, in thousands:

	March 31, 2016
	(unaudited)
Less Than 1 Year	$	25,427
1-5 years	68,790
Greater Than 5 Years	—
Total	$	94,217

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Inventories (Tables)

3 Months Ended

Mar. 31, 2016

Inventories

Schedule of inventories

Inventories consist of the following, in thousands:

	March 31,		December 31,		March 31,
	2016		2015		2015
	(unaudited)				(unaudited)
Raw materials	$	2,371	$	2,887	3,132
Work in process	4,264		3,946		6,328
Finished goods	6,409		5,754		4,242
	$	13,044	$	12,587	$	13,702

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Property and Equipment (Tables)

3 Months Ended

Mar. 31, 2016

Property and Equipment

Schedule of property and equipment

Property and equipment consist of the following, in thousands:

	March 31,			December 31,			March 31,
	2016			2015			2015
	(unaudited)						(unaudited)
Computer equipment	$	1,130		$	1,112		$	932
Software	1,463			307			314
Lab equipment and furniture	5,878			5,667			5,235
Leasehold improvements	2,642			2,642			2,446
Construction in progress	8			1,114			—
	11,121			10,842			8,927
Less accumulated depreciation and amortization	(7,255		)	(6,968		)	(6,446		)
	$	3,866		$	3,874		$	2,481

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Deferred Legal Fees and Intangible Assets (Tables)

3 Months Ended

Mar. 31, 2016

Deferred Legal Fees and Intangible Assets

Schedule of gross carrying amount and related accumulated amortization of the intangible assets

The following sets forth the gross carrying amount and related accumulated amortization of the intangible asset, in thousands:

		March 31, 2016
		(unaudited)				December 31, 2015
	Weighted-	Gross Carrying		Accumulated		Gross Carrying		Accumulated
	Average Life	Amount		Amortization		Amount		Amortization
Capitalized patent defense costs	9.5	$	16,267	$	159	$	994	$	18

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Accrued Expenses (Tables)

3 Months Ended

Mar. 31, 2016

Accrued Expenses

Schedule of accrued expenses

Accrued expenses are comprised of the following, in thousands, (restated):

	March 31,		December 31,		March 31
	2016		2015		2015
	(unaudited)				(unaudited)
Accrued professional fees	$	9,870	$	10,057	$	3,546
Accrued compensation	5,523		7,519		7,334
Accrued clinical trial and clinical supply costs	2,498		3,677		1,698
Accrued interest expense	393		295		646
Accrued sales and marketing expenses	1,139		434		1,657
Accrued product costs	11		113		131
Other accrued expenses	3,481		3,058		1,470
	$	22,915	$	25,153	$	16,482

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Convertible Senior Secured Notes (Tables)

3 Months Ended

Mar. 31, 2016

Convertible Senior Secured Notes

Summary of issuance of Notes reflected in balance sheet

The table below summarizes activity related to the Notes from issuance on May 3, 2013 through March 31, 2016, in thousands:

Gross proceeds	$	90,000
Initial value of interest make-whole derivative reported as debt discount	(9,270		)
Conversion option reported as debt discount and APIC	(22,336		)
Conversion of debt to equity - principal	(81,463		)
Conversion of debt to equity - accretion of debt discount and deferred financing costs	25,003
Accretion of debt discount and deferred financing costs	5,151
December 31, 2015 carrying value, restated	7,085
Conversion of debt to equity - principal	(1,962		)
Conversion of debt to equity - accretion of debt discount and deferred financing costs	424
Accretion of debt discount and deferred financing costs	80
March 31, 2016 carrying value, unaudited	$	5,627

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Summary Stockholders' Equity (Tables)

3 Months Ended

Mar. 31, 2016

Summary Stockholders' Equity

Schedule of activity in certain captions within Stockholders' Equity

The following summary table provides details related to the activity in certain captions within Stockholders’ Equity for the three month period ended March 31, 2016, in thousands.

	Common Stock		Additional Paid-in Capital
	(unaudited)
Balance, December 31, 2015	$	49	$	263,955
Share-based compensation	—		1,359
Exercise of stock options	—		124
Equity issued on note conversion			2,138
Balance, March 31, 2016	$	49	$	267,576

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Share-Based Payments (Tables)

3 Months Ended

Mar. 31, 2016

Share-Based Payments

Schedule of share-based compensation recognized related to the grant of employee and non-employee stock options, SARS and non-vested stock

Share-based compensation recognized related to the grant of employee and non-employee stock options, SAR, potential Employee Stock Purchase Plan (ESPP) awards and non-vested stock was as follows, in thousands:

	March 31,
	2016		2015
	(unaudited)
Research and development	$	288	$	204
Selling, general and administrative	1,071		698
Total	$	1,359	$	902

Summary of stock option and SAR activity

	Number of Options		Weighted- Average Exercise Price		Weighted- Average Remaining Contractual Term (in years)
Outstanding, December 31, 2015	2,699,007		$	8.94	7.92
Granted (unaudited)	1,016,750		$	12.98
Exercised (unaudited)	(25,807	)	$	4.79
Forfeited or expired (unaudited)	(1,250	)	$	10.33
Outstanding, March 31, 2016 (unaudited)	3,688,700		$	10.08	8.31
As of December 31, 2015:
Vested and expected to vest	2,654,381		$	8.93	7.90
Exercisable	901,672		$	7.95	6.86
As of March 31, 2016:
Vested and expected to vest (unaudited)	3,605,090		$	10.05	8.28
Exercisable (unaudited)	1,472,911		$	8.36	7.22

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Earnings per Share (Tables)

3 Months Ended

Mar. 31, 2016

Earnings per Share

Schedule of common stock equivalents excluded in the calculation of diluted loss per share

	Three Months ended March 31,
	2016	2015
	(unaudited)
Shares underlying Convertible Senior Secured Notes	—	6,071,894
Warrants to purchase common stock	—	21,800

Schedule of computation of basic and diluted net income per share

The following table sets forth the computation of basic and diluted net income per share for the three months ended March 31, 2016 and March 31, 2015, in thousands, except share and per share amounts, restated:

	Three Months ended March 31,
	2016			2015
	(unaudited)
Numerator, in thousands:
Net income used for calculation of basic EPS	$	4,825		$	738
Interest expense on convertible debt	179			—
Changes in fair value of derivative liabilities	(101		)	—
Loss on extinguishment of debt	382
Loss on extinguishment of outstanding debt, as if converted	(1,229		)	—
Total adjustments	(769		)	—
Net income used for calculation of diluted EPS	$	4,056		$	738
Denominator:
Weighted average shares outstanding, basic	49,240,099			44,563,299
Effect of dilutive potential common shares:
Shares underlying Convertible Senior Secured Notes	1,383,472			—
Shares issuable to settle interest make-whole derivatives	71,537			—
Stock options, stock appreciation rights, and non-vested stock options	456,964			337,999
Total potential dilutive common shares	1,911,973			337,999
Weighted average shares outstanding, diluted	51,152,072			44,901,298
Net income per share, basic	$	0.10		$	0.02
Net income per share, diluted	$	0.08		$	0.02

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Commitments and Contingencies (Tables)

3 Months Ended

Mar. 31, 2016

Commitments and Contingencies

Schedule of future minimum lease payments under non-cancelable operating leases

Future minimum lease payments under non-cancelable operating leases as of March 31, 2016 are as follows, in thousands, unaudited:

Year ending December 31:
2016 (remaining)	$	1,027
2017	1,294
2018	1,314
2019	1,341
Thereafter	454
	$	5,430

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Organization and Business (Details)	3 Months Ended
	Mar. 31, 2016 product
Organization and Business
Number of proprietary products in clinical development	2

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Restatement of Financial Statements - Consolidated Statement of Operations (Details) - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2016	Mar. 31, 2015
Impact of Restatement on the Condensed Consolidated Financial Statements
Maturity of Time Deposits	91 days
Royalty revenues	$ 1,119	$ 605
Total revenue	44,194	28,738
Selling, general and administrative	25,160	19,403
Total costs and expenses	37,757	24,704
Operating income (loss)	6,437	4,034
Interest expense non-recourse liability related to sale of future royalties	(1,279)	(759)
Total other expense	(1,412)	(3,210)
Earnings (loss) before income taxes	5,025	824
Income tax expense	200	86
Net income (loss)	4,825	738
As Previously Reported
Impact of Restatement on the Condensed Consolidated Financial Statements
Total revenue	43,075	28,133
Selling, general and administrative		19,402
Total costs and expenses		24,703
Operating income (loss)	5,318	3,430
Total other expense	(133)	(2,451)
Earnings (loss) before income taxes	5,185	979
Income tax expense	198	62
Net income (loss)	4,987	917
Restatement Adjustments
Impact of Restatement on the Condensed Consolidated Financial Statements
Royalty revenues	1,119	605
Total revenue	1,119	605
Operating income (loss)	1,119	605
Interest expense non-recourse liability related to sale of future royalties	(1,279)	(759)
Total other expense	(1,279)	(759)
Earnings (loss) before income taxes	(160)	(154)
Net income (loss)	(160)	(154)
Other Corrections
Impact of Restatement on the Condensed Consolidated Financial Statements
Selling, general and administrative		1
Total costs and expenses		1
Operating income (loss)		(1)
Earnings (loss) before income taxes		(1)
Income tax expense	2	24
Net income (loss)	$ (2)	$ (25)

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Restatement of Financial Statements - Consolidated Statements of Cash Flows (Details) - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2016	Mar. 31, 2015
Impact of Restatement on the Condensed Consolidated Financial Statements
Net cash provided by (used in) operating activities	$ (3,142)	$ (265)
Net cash used in investing activities	(10,650)	(11,120)
Net cash provided by financing activities	124	147
Net change in cash and cash equivalents	(13,668)	(11,238)
As Previously Reported
Impact of Restatement on the Condensed Consolidated Financial Statements
Net cash provided by (used in) operating activities		503
Net cash used in investing activities	(11,304)	(11,236)
Net change in cash and cash equivalents	(14,322)	(10,586)
Other Corrections
Impact of Restatement on the Condensed Consolidated Financial Statements
Net cash provided by (used in) operating activities		(768)
Net cash used in investing activities	654	116
Net change in cash and cash equivalents	$ 654	$ (652)

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Restatement of Financial Statements - Consolidated Balance Sheet (Details) - USD ($) $ in Thousands	Mar. 31, 2016	Dec. 31, 2015	Mar. 31, 2015	Dec. 31, 2014
Impact of Restatement on the Condensed Consolidated Financial Statements
Cash and cash equivalents	$ 19,830	$ 33,498	$ 25,158	$ 36,396
Marketable securities	25,427	28,692	39,678
Accrued expenses	22,915	25,153	16,482
Non-recourse liability related to sale of future royalties - current portion	1,067	497
Total current liabilities	55,533	56,934	27,509
Non-recourse liability related to sale of future royalties - long term	29,621	30,031	30,179
Total liabilities	97,365	100,619	75,654
Additional paid-in capital	267,576	263,955	252,483
Accumulated deficit	(170,684)	(175,509)	(188,715)
Total stockholders' equity	97,109	88,007	63,751
As Previously Reported
Impact of Restatement on the Condensed Consolidated Financial Statements
Cash and cash equivalents		34,152	25,810
Marketable securities		28,038	39,026
Accrued expenses	22,573	24,813	15,828
Total current liabilities	54,124	56,097	26,855
Total liabilities	66,335	69,751	45,053
Additional paid-in capital			252,341
Accumulated deficit	(139,654)	(144,641)	(157,740)
Total stockholders' equity	128,139	118,875	94,584
Restatement Adjustments
Impact of Restatement on the Condensed Consolidated Financial Statements
Non-recourse liability related to sale of future royalties - current portion	1,067	497
Total current liabilities	1,067	497
Non-recourse liability related to sale of future royalties - long term	29,621	30,031	30,179
Total liabilities	30,688	30,528	30,179
Accumulated deficit	(30,688)	(30,528)	(30,179)
Total stockholders' equity	(30,688)	(30,528)	(30,179)
Other Corrections
Impact of Restatement on the Condensed Consolidated Financial Statements
Cash and cash equivalents		(654)	(652)
Marketable securities		654	652
Accrued expenses	342	340	654
Total current liabilities	342	340	654
Total liabilities	342	340	422
Additional paid-in capital			142
Accumulated deficit	(342)	(340)	(796)
Total stockholders' equity	$ (342)	$ (340)	$ (654)

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Summary of Significant Accounting Policies - Segments (Details)	3 Months Ended
	Mar. 31, 2016 segment
Basis of Presentation
Number of operating segments	1

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Summary of Significant Accounting Policies - SERP (Details) - USD ($)	Mar. 31, 2016	Dec. 31, 2015
Supplemental Employee Retirement Plan, Defined Benefit [Member]
Marketable Securities - Restricted
Marketable securities - restricted	$ 255,000	$ 263,000

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Summary of Significant Accounting Policies - Accounts Receivable, net (Details) - USD ($) $ in Millions	3 Months Ended	12 Months Ended
	Mar. 31, 2016	Dec. 31, 2015
Accounts Receivable, net
Accounts receivable written off	$ 0.0	$ 0.0
Allowance for expected sales deductions	$ 4.0	$ 3.8
Convertible Notes Payable [Member]
Deferred Financing Costs
Interest rate (as a percent)	7.50%

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Summary of Significant Accounting Policies - Revenue Recognition (Details) - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2016	Mar. 31, 2015	Sep. 30, 2014
Royalty Revenue [Abstract]
Non-recourse liability related to sale of future royalties			$ 30,000
Royalty revenues	$ 1,119	$ 605
Non-cash interest expense/income on liability related to sale of future royalties	$ 1,279	759
Sales return period prior to expiry date	6 months
Sales return period subsequent to expiry date	12 months
Milestone revenues recorded	$ 0	$ 0

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Summary of Significant Accounting Policies - Recently Issued Accounting Pronouncements (Details) - USD ($)	Mar. 31, 2016	Dec. 31, 2015	Mar. 31, 2015
Simplifying the Presentation of Debt Issuance Costs
Assets	$ 194,474,000	$ 188,626,000	$ 139,405,000
Liabilities	$ 97,365,000	100,619,000	75,654,000
Accounting Standards Update ("ASU") 2015-03 - Simplifying the Presentation of Debt Issuance Costs
Simplifying the Presentation of Debt Issuance Costs
Assets		(104,000)	(232,000)
Liabilities		$ (104,000)	$ (232,000)

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Fair Value of Financial Instruments - Carrying Value (Details) - USD ($) $ in Thousands	Mar. 31, 2016	Dec. 31, 2015	Mar. 31, 2015
Assets:
Marketable securities	$ 25,427	$ 28,692	$ 39,678
Long term marketable securities	68,790	55,009	27,315
Liabilities:
Derivative liabilities	535	854	2,691
Total Carrying Value | Recurring
Assets:
Cash and cash equivalents	19,830	33,498	25,158
Marketable securities	25,427	28,692	39,678
Long term marketable securities	68,790	55,009	27,315
Marketable securities - restricted (SERP)	255	263	267
Total assets at fair value	114,302	117,462	92,418
Liabilities:
Derivative liabilities	535	854	2,691
Quoted Prices in Active Markets (Level 1) | Recurring
Assets:
Cash and cash equivalents	19,830	33,498	25,158
Marketable securities	654	654	652
Total assets at fair value	20,484	34,152	25,810
Significant Other Observable Inputs (Level 2) | Recurring
Assets:
Marketable securities	24,773	28,038	39,026
Long term marketable securities	68,790	55,009	27,315
Marketable securities - restricted (SERP)	255	263	267
Total assets at fair value	93,818	83,310	66,608
Significant Unobservable Inputs (Level 3) | Recurring
Liabilities:
Derivative liabilities	$ 535	$ 854	$ 2,691

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Fair Value of Financial Instruments - Fair Value Assumptions (Details)	3 Months Ended
	Mar. 31, 2016 $ / shares
Assumptions used to calculate fair value of interest make-whole liability using Monte-Carlo simulation with a Black-Scholes lattice model
Volatility (as a percent)	45.00%
Stock Price (in dollars per share)	$ 15.21
Credit Spread (as a percent)	9.00%
Term	1 year 1 month 6 days
Dividend Yield (as a percent)	0.00%
Convertible Notes Payable [Member]
Assumptions used to calculate fair value of interest make-whole liability using Monte-Carlo simulation with a Black-Scholes lattice model
Interest rate (as a percent)	7.50%

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Fair Value of Financial Instruments - Level 3 (Details) - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2016	Dec. 31, 2015	Mar. 31, 2015
Interest Make-Whole Liability
Carrying value of the convertible notes	$ 5,627	$ 7,085	$ 11,476
Face value of the convertible notes	6,600
Estimated fair value of the convertible notes	20,000
Significant Unobservable Inputs (Level 3) | Derivative Financial Instruments, Liabilities [Member]
Interest Make-Whole Liability
Balance at the beginning of the period	854
Changes in fair value of derivative liabilities included in earnings	(101)
Reduction due to conversion of debt to equity	(218)
Balance at the end of the period	$ 535

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Fair Value of Financial Instruments - Unrestricted Marketable Securities (Details) - USD ($) $ in Thousands	Mar. 31, 2016	Dec. 31, 2015	Mar. 31, 2015
Fair Value of Financial Instruments
Corporate debt securities, Amortized Cost	$ 94,049	$ 84,189	$ 67,058
Corporate debt securities, Gross Unrealized Gains	300	5	15
Corporate debt securities, Gross Unrealized Losses	(132)	(493)	(80)
Corporate debt securities, Fair Value	94,217	83,701	66,993
Contractual maturities of the unrestricted marketable securities held
Less Than 1 Year	25,427
1-5 years	68,790
Corporate debt securities, Fair Value	$ 94,217	$ 83,701	$ 66,993

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Inventories (Details) - USD ($) $ in Thousands	Mar. 31, 2016	Dec. 31, 2015	Mar. 31, 2015
Inventories
Raw materials	$ 2,371	$ 2,887	$ 3,132
Work in process	4,264	3,946	6,328
Finished goods	6,409	5,754	4,242
Total inventories	$ 13,044	$ 12,587	$ 13,702

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Property and Equipment (Details) - USD ($)	3 Months Ended
	Mar. 31, 2016	Mar. 31, 2015	Dec. 31, 2015
Property and equipment
Property and equipment, gross	$ 11,121,000	$ 8,927,000	$ 10,842,000
Less accumulated depreciation and amortization	(7,255,000)	(6,446,000)	(6,968,000)
Property and equipment, net	3,866,000	2,481,000	3,874,000
Depreciation and amortization expense	287,000	156,000
Computer Equipment [Member]
Property and equipment
Property and equipment, gross	1,130,000	932,000	1,112,000
Computer Software, Intangible Asset [Member]
Property and equipment
Property and equipment, gross	1,463,000	314,000	307,000
Lab Equipment and Furniture [Member]
Property and equipment
Property and equipment, gross	5,878,000	5,235,000	5,667,000
Leasehold Improvements [Member]
Property and equipment
Property and equipment, gross	2,642,000	$ 2,446,000	2,642,000
Construction in progress
Property and equipment
Property and equipment, gross	$ 8,000		$ 1,114,000

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Deferred Legal Fees and Intangible Assets (Details) - USD ($)	3 Months Ended		12 Months Ended
	Mar. 31, 2016	Mar. 31, 2015	Dec. 31, 2015
Additional disclosures
Deferred legal fees	$ 11,444,000	$ 7,672,000	$ 22,503,000
Net book value of intangible assets	16,108,000	167,000	$ 976,000
Amortization expense	$ 142,000	$ 57,000
Patent Defense Costs [Member]
Finite lived intangible assets disclosures
Weighted-Average Life	9 years 6 months		9 years 6 months
Gross Carrying Amount	$ 16,267,000		$ 994,000
Accumulated Amortization	$ 159,000		$ 18,000

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Accrued Expenses (Details) - USD ($) $ in Thousands	Mar. 31, 2016	Dec. 31, 2015	Mar. 31, 2015
Accrued Expenses
Accrued professional fees	$ 9,870	$ 10,057	$ 3,546
Accrued compensation	5,523	7,519	7,334
Accrued clinical trial and clinical supply costs	2,498	3,677	1,698
Accrued interest expense	393	295	646
Accrued sales and marketing expenses	1,139	434	1,657
Accrued product costs	11	113	131
Other accrued expenses	3,481	3,058	1,470
Total	$ 22,915	$ 25,153	$ 16,482

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Convertible Senior Secured Notes (Details) - USD ($)	3 Months Ended		32 Months Ended
	Mar. 31, 2016	Mar. 31, 2015	Dec. 31, 2015
Details of Notes reflected in balance sheet
Remaining outstanding balance	$ 5,627,000	$ 11,476,000	$ 7,085,000
Loss on extinguishment of debt	382,000	2,134,000
Convertible Notes Payable [Member]
Details of Notes reflected in balance sheet
Gross proceeds			90,000,000
Initial value of interest make-whole derivative reported as debt discount			(9,270,000)
Conversion option reported as debt discount and APIC			(22,336,000)
Conversion of debt to equity - principal	(1,962,000)	(21,400,000)	(81,463,000)
Conversion of debt to equity - accretion of debt discount and deferred financing costs	424,000		25,003,000
Accretion of debt discount and deferred financing costs	80,000		5,151,000
Remaining outstanding balance	$ 5,627,000		$ 7,085,000
Shares of common stock issued in conversion of Notes	400,000
Shares of common stock issued in settlement of the interest make-whole provision	21,000
Loss on extinguishment of debt	$ 400,000	$ 2,100,000

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Summary Stockholders' Equity (Details) $ in Thousands	3 Months Ended
	Mar. 31, 2016 USD ($)
Beginning balance	$ 88,007
Ending balance	97,109
Common Stock [Member]
Beginning balance	49
Ending balance	49
Additional Paid-in Capital [Member]
Beginning balance	263,955
Share-based compensation	1,359
Exercise of stock options	124
Equity issued on note conversion	2,138
Ending balance	$ 267,576

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Share-Based Payments - 2012 Plan (Details) - 2012 Plan	3 Months Ended
	Mar. 31, 2016 installment shares
Share-based payments
Maximum number of shares of common stock provided for issuance | shares	4,000,000
Stock Option
Share-based payments
Number of annual installments in which the awards would generally vest starting on the first anniversary of the date of grant | installment	4
Contractual term	10 years
Directors | Stock Option
Share-based payments
Vesting period	1 year

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Share-Based Payments - Share-based Compensation Expense (Details) - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2016	Mar. 31, 2015
Share-based Payments
Share-based compensation recognized	$ 1,359	$ 902
Research and Development Expense [Member]
Share-based Payments
Share-based compensation recognized	288	204
Selling, General and Administrative Expenses [Member]
Share-based Payments
Share-based compensation recognized	$ 1,071	$ 698

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Share-Based Payments - Activity (Details) - Stock option and Stock Appreciation Rights - $ / shares	3 Months Ended	12 Months Ended
	Mar. 31, 2016	Dec. 31, 2015
Number of Options and SAR
Outstanding at the beginning of the period (in shares)	2,699,007
Granted (in shares)	1,016,750
Exercised (in shares)	(25,807)
Forfeited and expired (in shares)	(1,250)
Outstanding at the end of the period (in shares)	3,688,700	2,699,007
Vested and expected to vest (in shares)	3,605,090	2,654,381
Exercisable (in shares)	1,472,911	901,672
Weighted-Average Exercise Price
Outstanding at the beginning of the period (in dollars per share)	$ 8.94
Granted (in dollars per share)	12.98
Exercised (in dollars per share)	4.79
Forfeited or expired (in dollars per share)	10.33
Outstanding at the end of the period (in dollars per share)	10.08	$ 8.94
Vested and expected to vest (in dollars per share)	10.05	8.93
Exercisable (in dollars per share)	$ 8.36	$ 7.95
Weighted-Average Remaining Contractual Term
Outstanding at the end of the period	8 years 3 months 22 days	7 years 11 months 1 day
Vested and expected to vest	8 years 3 months 11 days	7 years 10 months 24 days
Exercisable	7 years 2 months 19 days	6 years 10 months 10 days

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Earnings per Share (Details) - USD ($) $ / shares in Units, $ in Thousands	3 Months Ended
	Mar. 31, 2016	Mar. 31, 2015
Numerator, in thousands:
Net income used for calculation of basic EPS	$ 4,825	$ 738
Interest expense on convertible debt	179
Changes in fair value of derivative liabilities	(101)
Loss on extinguishment of debt	382
Loss on extinguishment of outstanding debt, as if converted	(1,229)
Total adjustments	(769)
Net income used for calculation of diluted EPS	$ 4,056	$ 738
Denominator:
Weighted average shares outstanding, basic	49,240,099	44,563,299
Effect of dilutive potential common shares:
Shares underlying Convertible Senior Secured Notes	1,383,472
Shares issuable to settle interest make-whole derivatives	71,537
Stock options, stock appreciation rights, and non-vested stock options	456,964	337,999
Total potential dilutive common shares	1,911,973	337,999
Weighted average shares outstanding, diluted	51,152,072	44,901,298
Net income per share, basic	$ 0.10	$ 0.02
Net income per share, diluted	$ 0.08	$ 0.02
Convertible Notes Payable [Member]
Loss Per Share
Common stock equivalents excluded in the calculation of diluted loss per share		6,071,894
Warrant [Member]
Loss Per Share
Common stock equivalents excluded in the calculation of diluted loss per share		21,800

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Income Taxes (Details) - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2016	Mar. 31, 2015
Income Taxes
Pre-tax income	$ 5,025	$ 824
Income tax expense	$ 200	$ 86

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Commitments and Contingencies (Details) - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2016	Mar. 31, 2015
Commitments and Contingencies
Additional period for which the entity may elect to extend the term of the lease	5 years
Additional tenant improvement allowance	$ 2,100
Tenant improvement allowance utilized and included in fixed assets and deferred rent	0	$ 0
Amount available for tenant improvements	500
Rent expense	700	$ 700
Future minimum lease payments under non-cancelable operating leases
2016 (remaining)	1,027
2017	1,294
2018	1,314
2019	1,341
Thereafter	454
Total	$ 5,430