UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

SCHEDULE 14A

PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE

SECURITIES EXCHANGE ACT OF 1934

(AMENDMENT NO.     )

Filed by the Registrant   þ                            Filed by a Party other than the Registrant  ¨

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¨ Preliminary Proxy Statement

¨ Confidential, For Use of the Commission Only (as permitted by Rule 14a-6(e)(2))

¨ Definitive Proxy Statement

þ Definitive Additional Materials

¨ Soliciting Material Pursuant to § 240.14a-12

INTREXON CORPORATION

(Name of Registrant as Specified in its Charter)

(Name of Person(s) Filing Proxy Statement, if other than the Registrant)

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*** Exercise Your Right to Vote ***

Important Notice Regarding the Availability of Proxy Materials for the

Shareholder Meeting to Be Held on June 11, 2015.

		Meeting Information
	INTREXON CORPORATION	Meeting Type: Annual Meeting
		For holders as of: April 16, 2015
		Date: June 11, 2015             Time: 9:30 AM, ET
		Location:    Esperante Conference Center                       222 Lakeview Avenue                       West Palm Beach, FL 33401
	INTREXON CORPORATION 222 LAKEVIEW AVE. SUITE 1400 WEST PALM BEACH, FL 33401	You are receiving this communication because you hold shares in the company named above. This is not a ballot. You cannot use this notice to vote these shares. This communication presents only an overview of the more complete proxy materials that are available to you on the Internet. You may view the proxy materials online at www.proxyvote.com or easily request a paper copy (see reverse side). We encourage you to access and review all of the important information contained in the proxy materials before voting.
		See the reverse side of this notice to obtain proxy materials and voting instructions .

—  Before You Vote  — How to Access the Proxy Materials
	Proxy Materials Available to VIEW or RECEIVE:
	NOTICE AND PROXY STATEMENT        ANNUAL REPORT How to View Online:
	Have the information that is printed in the box marked by the arrow (located on the following page) and visit: www.proxyvote.com. How to Request and Receive a PAPER or E-MAIL Copy: If you want to receive a paper or e-mail copy of these documents, you must request one. There is NO charge for requesting a copy. Please choose one of the following methods to make your request:
		1) BY INTERNET:	www.proxyvote.com
		2) BY TELEPHONE:	1-800-579-1639
		3) BY E-MAIL*:	sendmaterial@proxyvote.com
	*  If requesting materials by e-mail, please send a blank e-mail with the information that is printed in the box marked by the arrow (located on the following page) in the subject line. Requests, instructions and other inquiries sent to this e-mail address will NOT be forwarded to your investment advisor. Please make the request as instructed above on or before May 25, 2015 to facilitate timely delivery.

	—  How To Vote  —
	Please Choose One of the Following Voting Methods
		Vote In Person: Many shareholder meetings have attendance requirements including, but not limited to, the possession of an attendance ticket issued by the entity holding the meeting. Please check the meeting materials for any special requirements for meeting attendance. At the meeting, you will need to request a ballot to vote these shares. Vote By Internet: To vote now by Internet, go to www.proxyvote.com. Have the information that is printed in the box marked by the arrow (located on the following page) available and follow the instructions. Vote By Mail: You can vote by mail by requesting a paper copy of the materials, which will include a proxy card.

Voting Items

	The Board of Directors recommends you vote FOR all of the following director nominees:		The Board of Directors recommends you vote FOR the following proposal:
	1.	Election of Directors Nominees:	2.      To approve a non-binding advisory resolution approving the compensation of the named executive officers.
		1a.     Randal J. Kirk 1b.     Cesar L. Alvarez 1c.     Steven Frank 1d.     Larry D. Horner 1e.     Jeffrey B. Kindler 1f.     Dean J. Mitchell 1g.     Robert B. Shapiro 1h.     James S. Turley	The Board of Directors recommends you vote for a ONE-YEAR frequency: 3.      To provide a non-binding advisory vote as to the frequency (every one, two or three years) of the non-binding shareholder vote to approve the compensation of our named executive officers. The Board of Directors recommends you vote FOR the following proposals: 4.      To ratify the appointment by the Audit Committee of PricewaterhouseCoopers LLP as our independent registered public accounting firm for the fiscal year ending December 31, 2015.
			5.      To approve the Amendment to the Amended and Restated Intrexon Corporation 2013 Omnibus Incentive Plan, which provides for the issuance of an additional three million shares of Common Stock under the plan.
			6.      To approve the Intrexon Corporation Annual Executive Incentive Plan. NOTE: Such other business as may properly come before the meeting or any adjournment thereof.