UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549 

SCHEDULE 14A

Proxy Statement Pursuant to Section 14(a) of the
Securities Exchange Act of 1934
(Amendment No. ___) 

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☐ Preliminary Proxy Statement

☐ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2))

☐ Definitive Proxy Statement

☒ Definitive Additional Materials

☐ Soliciting Material Pursuant to §240.14a-12

Precigen, Inc.
(Name of Registrant as Specified In Its Charter)

(Name of Person(s) Filing Proxy Statement, if Other Than The Registrant)

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Your Vote Counts! PRECIGEN, INC. 20374 SENECA MEADOWS PARKWAY GERMANTOWN, MARYLAND 20876 PRECIGEN, INC. 2022 Annual Meeting Vote by June 8, 2022 11:59 PM ET Vote Virtually at the Meeting* June 9, 2022 9:00 AM EDT Virtually at: www.virtualshareholdermeeting.com/PGEN2022 *Please check the meeting materials for any special requirements for meeting attendance. Smartphone users Point your camera here and vote without entering a control number V1.1 For complete information and to vote, visit www.ProxyVote.com Control # D82350 - P70697 You invested in PRECIGEN, INC. and it’s time to vote! You have the right to vote on proposals being presented at the Annual Meeting. This is an important notice regarding the availability of proxy material for the shareholder meeting to be held on June 9, 2022. Get informed before you vote View the Annual Report and Proxy Statement online OR you can receive a free paper or email copy of the material(s) by requesting prior to May 26, 2022. If you would like to request a copy of the material(s) for this and/or future shareholder meetings, you may (1) visit www.ProxyVote.com, (2) call 1 - 800 - 579 - 1639 or (3) send an email to sendmaterial@proxyvote.com. If sending an email, please include your control number (indicated below) in the subject line. Unless requested, you will not otherwise receive a paper or email copy.

Vote at www.ProxyVote.com THIS IS NOT A VOTABLE BALLOT This is an overview of the proposals being presented at the upcoming shareholder meeting. Please follow the instructions on the reverse side to vote these important matters. Prefer to receive an email instead? While voting on www.ProxyVote.com, be sure to click “Sign up for E - delivery”. Voting Items Board Recommends D82351 - P70697 1. Company Proposal – Election of Directors Nominees: 1a. Randal Kirk For 1b. Cesar Alvarez For 1c. Steven Frank For 1d. Vinita Gupta For 1e. Fred Hassan For 1f. Jeffrey Kindler For 1g. Dean Mitchell For 1h. Helen Sabzevari For 1i. Robert Shapiro For 1j. James Turley For 2. Company Proposal – Ratify the appointment of Deloitte & Touche LLP as our independent registered public accounting firm for fiscal year ending December 31, 2022. For 3. Company Proposal – Advisory vote on executive compensation. For 4. Company Proposal – Approval of an amendment to the Precigen, Inc. Amended and Restated 2013 Omnibus Incentive Plan to increase the number of shares of common stock which may be subject to awards thereunder by 10 million. For 5. Company Proposal – Approval of an amendment to the Precigen, Inc. 2019 Incentive Plan for Non - Employee Service Providers to increase the number of shares of common stock which may be subject to awards thereunder by 7 million. For NOTE: In their discretion, the proxies are authorized to vote on such other business as may properly come before the meeting or any adjournment thereof. You may attend the meeting and vote during the meeting when the polls are open via the Internet . We recommend, however, that you vote before the meeting even if you plan to participate in the meeting . When voting, have the information that is printed in the box marked by the arrow and follow instructions .