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Convertible Preferred Stock and Stockholders' Deficit - Summary of Stock Option Activity (Detail) - 2006 Plan and 2010 Plan [Member]
6 Months Ended
Jun. 30, 2023
$ / shares
shares
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]  
Number of Outstanding Options, Outstanding, Beginning balance | shares 6,858,492
Number of Outstanding Options, Granted | shares 2,450,410
Number of Outstanding Options, Expired | shares (1,354)
Number of Outstanding Options, Outstanding, Ending balance | shares 9,307,548
Number of Outstanding Options, Vested and expected to vest at June 30, 2023 | shares 8,838,409
Number of Outstanding Options, Exercisable at June 30, 2023 | shares 5,273,248
Weighted Average Exercise, Outstanding, Beginning balance | $ / shares $ 1.02
Weighted Average Exercise, Granted | $ / shares 0.14
Weighted Average Exercise Price, Expired | $ / shares 40.5
Weighted Average Exercise, Outstanding, Ending balance | $ / shares 0.78
Weighted Average Exercise, Vested and expected to vest at June 30, 2023 | $ / shares 0.81
Weighted Average Exercise, Exercisable at June 30, 2023 | $ / shares $ 1.19
Weighted Average Remaining Contractual Term (in years), Options Outstanding Ending Balance 7 years 8 months 8 days
Weighted Average Remaining Contractual Term (in years), Vested and expected to vest at June 30, 2023 7 years 7 months 2 days
Weighted Average Remaining Contractual Term (in years), Exercisable at June 30, 2023 6 years 4 months 6 days