Exhibit 99.100

	1500 Robert-Bourassa Blvd.
April 15, 2019	7th Floor
	Montreal QC, H3A 3S8
	www.computershare.com

To: All Canadian Securities Regulatory Authorities

Subject: Prometic Life Sciences Inc.

Dear Sir/Madam:

We advise of the following with respect to the upcoming Meeting of Security Holders for the subject Issuer:

Meeting Type :	Annual General and Special Meeting
Record Date for Notice of Meeting :	May 10, 2019
Record Date for Voting (if applicable) :	May 10, 2019
Beneficial Ownership Determination Date :	May 10, 2019
Meeting Date :	June 19, 2019
Meeting Location (if available) :	Montréal, QC
Issuer sending proxy related materials directly to NOBO:	No
Issuer paying for delivery to OBO:	Yes
Notice and Access (NAA) Requirements:
NAA for Beneficial Holders	Yes
Beneficial Holders Stratification Criteria:	Not Applicable
NAA for Registered Holders	Yes
Registered Holders Stratification Criteria:	Not Applicable

Voting Security Details:

Description	CUSIP Number	ISIN
COMMON SHARES	74342Q104	CA74342Q1046

Sincerely,

Computershare

Agent for Prometic Life Sciences Inc.