Balance Sheet Details - Accrued Expenses (Detail) (USD $) In Thousands, unless otherwise specified	Dec. 31, 2012	Dec. 31, 2011
Accrued Expenses [Line Items]
Legal	$ 939	$ 249
Accounting	847	1,033
Phygen purchase price payable	3,936
Severance	749
Restructuring		123
Sales milestones	2,423	2,344
Accrued taxes payable	1,605	1,457
Deferred rent	1,483	1,746
Royalties	1,911	2,409
Commissions	5,371	4,120
Payroll and related	7,027	6,348
Litigation settlement	4,102	7,000
Other	8,097	5,754
Total accrued expenses	$ 38,490	$ 32,583