CONSOLIDATED STATEMENT OF CHANGES IN SHAREHOLDERS' EQUITY - USD ($)	Total	Common Stock [Member]	Capital in Excess of Par Value [Member]	Accumulated Other Comprehensive Income [Member]	Accumulated Deficit [Member]
Beginning balance at Dec. 31, 2015	$ 11,728,500	$ 710	$ 78,284,815	$ 0	$ (66,557,025)
Beginning balance (in shares) at Dec. 31, 2015		71,006,844
Stock issued in February 2016 registered direct offering, net	5,091,791	$ 50	5,091,741	0	0
Stock issued in February 2016 registered direct offering, net (in shares)		5,000,000
Stock issued in July 2016 registered direct offering, net	4,682,764	$ 62	4,682,702	0	0
Stock issued in July 2016 registered direct offering, net (in shares)		6,172,840
Stock issued in October 2016 registered direct offering, net	10,707,823	$ 85	10,707,738	0	0
Stock issued in October 2016 registered direct offering, net (in shares)		8,500,000
Stock issued in connection with warrant exercises	196	$ 0	196	0	0
Stock issued in connection with warrant exercises (in shares)		2,618
Equity-based compensation	$ 894,715	$ 0	894,715	0	0
Equity-based compensation (in shares)	0	15,811
Reclassification of warrant liability to capital in excess of par	$ 2,810,000	$ 0	2,810,000	0	0
Unrealized loss on short-term investment securities, net of tax	0
Reclassification of losses to net loss, net of tax	0
Net loss	(11,581,430)	0	0	0	(11,581,430)
Ending balance at Dec. 31, 2016	24,334,359	$ 907	102,471,907	0	(78,138,455)
Ending balance (in shares) at Dec. 31, 2016		90,698,113
Stock issued in connection with warrant exercises	12,447,108	$ 122	12,446,986	0	0
Stock issued in connection with warrant exercises (in shares)		12,249,327
Stock issued in connection with stock option exercises	0	$ 1	(1)	0	0
Stock issued in connection with stock option exercises (in shares)		51,927
Equity-based compensation	941,650	$ 0	941,650	0	0
Equity-based compensation (in shares)		0
Unrealized loss on short-term investment securities, net of tax	0
Stock issued in October 2017 registered direct offering, net	50,732,200	$ 206	50,731,994	0	0
Stock issued in October 2017 registered direct offering, net (in shares)		20,570,000
Reclassification of losses to net loss, net of tax	0
Net loss	(13,029,117)	$ 0	0	0	(13,029,117)
Ending balance at Dec. 31, 2017	75,426,200	$ 1,236	166,592,536	0	(91,167,572)
Ending balance (in shares) at Dec. 31, 2017		123,569,367
Stock issued in connection with warrant exercises	0	$ 5	(5)	0	0
Stock issued in connection with warrant exercises (in shares)		490,012
Stock issued in connection with stock option exercises	444,613	$ 5	444,608	0	0
Stock issued in connection with stock option exercises (in shares)		583,214
Equity-based compensation	3,187,331	$ 0	3,187,331	0	0
Equity-based compensation (in shares)		0
Reclassification of warrant liability to capital in excess of par	167,779	$ 0	167,779	0	0
Unrealized loss on short-term investment securities, net of tax	(21,653)	0	0	(21,653)	0
Reclassification of losses to net loss, net of tax	43,016			43,016
Net loss	(7,966,911)	0	0	0	(7,966,911)
Ending balance at Dec. 31, 2018	$ 71,280,375	$ 1,246	$ 170,392,249	$ 21,363	$ (99,134,483)
Ending balance (in shares) at Dec. 31, 2018		124,642,593