Income Taxes - Additional Information (Details) - USD ($) $ in Millions	12 Months Ended
	Dec. 31, 2023	Dec. 31, 2022	Dec. 31, 2021
Income Taxes [Line Items]
U.S. research and development credit beginning expiration year	2031
Orphan drug credit beginning expiration year	2030
Deferred tax assets relating to U.S. state NOL carryforwards	$ 5.9
Cash paid for income taxes	3.6	$ 0.0	$ 0.0
Unrecognized tax benefits that would impact effective tax rate	18.3
Research Tax Credit Carryforward
Income Taxes [Line Items]
Deferred tax assets related to U.S. federal research and development credits	16.1
Orphan Drug
Income Taxes [Line Items]
Net deferred tax assets	$ 22.5
District of Columbia
Income Taxes [Line Items]
Net operating loss carryforwards beginning expiration year	2032
Other States
Income Taxes [Line Items]
Net operating loss carryforwards beginning expiration year	2034