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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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MIC-Info: RSA-MD5,RSA,
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<SEC-DOCUMENT>9999999995-10-001375.txt : 20100506
<SEC-HEADER>9999999995-10-001375.hdr.sgml : 20100506
<ACCEPTANCE-DATETIME>20100506001510
ACCESSION NUMBER:		9999999995-10-001375
CONFORMED SUBMISSION TYPE:	EFFECT
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20100505
DATE AS OF CHANGE:		20100506
EFFECTIVENESS DATE:		20100505

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Alexza Pharmaceuticals Inc.
		CENTRAL INDEX KEY:			0001344413
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				770567768
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		EFFECT
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-141739
		FILM NUMBER:		10803764

	BUSINESS ADDRESS:	
		STREET 1:		2091 STIERLIN COURT
		CITY:			MOUNTAIN VIEW
		STATE:			CA
		ZIP:			94043
		BUSINESS PHONE:		650.944.7000

	MAIL ADDRESS:	
		STREET 1:		2091 STIERLIN COURT
		CITY:			MOUNTAIN VIEW
		STATE:			CA
		ZIP:			94043
</SEC-HEADER>
<DOCUMENT>
<TYPE>EFFECT
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
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<?xml version="1.0"?>
<edgarSubmission>

    <schemaVersion>X0101</schemaVersion>

    <submissionType>EFFECT</submissionType>

    <act>33</act>

    <testOrLive>LIVE</testOrLive>

    <effectiveData>
        <finalEffectivenessDispDate>2010-05-05</finalEffectivenessDispDate>
        <accessionNumber>0000950123-10-043561</accessionNumber>
        <submissionType>POS AM</submissionType>
        <filer>
            <cik>0001344413</cik>
            <entityName>Alexza Pharmaceuticals Inc.</entityName>
            <fileNumber>333-141739</fileNumber>
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