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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
Originator-Key-Asymmetric:
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 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 PVr5dd09lc2vS3jOq9Rs1+JldQIlzvOnFIuqfa82RZXU5Vntq7ao2M6aiq8XvoGj
 4ROWPUg4Rb8V11BJFRXNhw==

<SEC-DOCUMENT>9999999995-09-002880.txt : 20091019
<SEC-HEADER>9999999995-09-002880.hdr.sgml : 20091019
<ACCEPTANCE-DATETIME>20091019001520
ACCESSION NUMBER:		9999999995-09-002880
CONFORMED SUBMISSION TYPE:	EFFECT
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20091016
DATE AS OF CHANGE:		20091019
EFFECTIVENESS DATE:		20091016

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Alexza Pharmaceuticals Inc.
		CENTRAL INDEX KEY:			0001344413
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				770567768
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		EFFECT
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-161804
		FILM NUMBER:		091124484

	BUSINESS ADDRESS:	
		STREET 1:		2091 STIERLIN COURT
		CITY:			MOUNTAIN VIEW
		STATE:			CA
		ZIP:			94043
		BUSINESS PHONE:		650.944.7000

	MAIL ADDRESS:	
		STREET 1:		2091 STIERLIN COURT
		CITY:			MOUNTAIN VIEW
		STATE:			CA
		ZIP:			94043
</SEC-HEADER>
<DOCUMENT>
<TYPE>EFFECT
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
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<?xml version="1.0"?>
<edgarSubmission>

    <schemaVersion>X0101</schemaVersion>

    <submissionType>EFFECT</submissionType>

    <act>33</act>

    <testOrLive>LIVE</testOrLive>

    <effectiveData>
        <finalEffectivenessDispDate>2009-10-16</finalEffectivenessDispDate>
        <finalEffectivenessDispTime>16:00:00</finalEffectivenessDispTime>
        <form>S-1</form>
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            <cik>0001344413</cik>
            <entityName>Alexza Pharmaceuticals Inc.</entityName>
            <fileNumber>333-161804</fileNumber>
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