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Summary of Significant Accounting Policies - Summary of Accounts Receivable (Parenthetical) (Detail) - CCX140 Agreement [Member] - USD ($)
$ in Millions
12 Months Ended
Dec. 31, 2016
Dec. 31, 2016
Accounts, Notes, Loans and Financing Receivable [Line Items]    
Cash commitment due $ 20.0  
Vifor (International) Ltd [Member]    
Accounts, Notes, Loans and Financing Receivable [Line Items]    
Cash commitment due   $ 20.0