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Accrued Liabilities - Accrued Liabilities (Detail) - USD ($)
$ in Thousands
Sep. 30, 2015
Dec. 31, 2014
Payables and Accruals [Abstract]    
Research and development related $ 2,225 $ 4,982
Compensation related 1,728 1,956
Consulting and Professional Services 516 254
Other 450 250
Accrued liabilities $ 4,919 $ 7,442