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Condensed Consolidated Statements of Operations (USD $)
In Thousands, except Share data, unless otherwise specified
3 Months Ended
Mar. 31, 2015
Mar. 31, 2014
Operating expenses:    
Research and development $ 6,593us-gaap_ResearchAndDevelopmentExpense $ 4,388us-gaap_ResearchAndDevelopmentExpense
General and administrative 2,329us-gaap_GeneralAndAdministrativeExpense 1,542us-gaap_GeneralAndAdministrativeExpense
Total operating expenses 8,922us-gaap_OperatingExpenses 5,930us-gaap_OperatingExpenses
Loss from operations (8,922)us-gaap_OperatingIncomeLoss (5,930)us-gaap_OperatingIncomeLoss
Other income (expense), net (149)us-gaap_OtherNonoperatingIncomeExpense (163)us-gaap_OtherNonoperatingIncomeExpense
Net loss (9,071)us-gaap_NetIncomeLoss (6,093)us-gaap_NetIncomeLoss
Accretion to redemption value of redeemable convertible preferred stock   (138)us-gaap_TemporaryEquityAccretionToRedemptionValueAdjustment
Net loss attributable to common stockholders $ (9,071)us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic $ (6,231)us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic
Net loss per share attributable to common stockholders, basic and diluted $ (9.39)us-gaap_EarningsPerShareBasicAndDiluted $ (7.87)us-gaap_EarningsPerShareBasicAndDiluted
Weighted average shares outstanding, basic and diluted 966,322us-gaap_WeightedAverageNumberOfShareOutstandingBasicAndDiluted 791,283us-gaap_WeightedAverageNumberOfShareOutstandingBasicAndDiluted